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Association of immunoglobulin G N-glycosylation with carotid atherosclerotic plaque phenotypes and actual clinical cardiovascular events: a study protocol for a longitudinal prospective cohort study
BMJ Open. 2022 Jul 22;12(7):e058922. doi: 10.1136/bmjopen-2021-058922.ABSTRACTINTRODUCTION: Immune-inflammatory response plays a key role in the pathogenesis of atherosclerosis. IgG N-glycosylation is reported to be associated with the 10-year atherosclerotic cardiovascular disease risk score and subclinical atherosclerosis. However, the relationship of IgG glycosylation with actual clinical cardiovascular disease (CVD) events and plaque phenotypes has rarely been investigated. Therefore, this study aims to understand whether IgG glycosylation traits are correlated with actual clinical CVD events and plaque phenotypes.METH...
Source: Atherosclerosis - July 22, 2022 Category: Cardiology Authors: Cuihong Tian Gehendra Mahara Hongxia Zhang Xuerui Tan Source Type: research

Lead exposure and its association with cardiovascular disease and diabetic kidney disease in middle-aged and elderly diabetic patients.
CONCLUSIONS: A high BLL may be a potential risk factor for CVD and DKD in middle-aged and elderly diabetic adults. PMID: 33212357 [PubMed - as supplied by publisher]
Source: International Journal of Hygiene and Environmental health - November 16, 2020 Category: Environmental Health Authors: Wan H, Chen S, Cai Y, Chen Y, Wang Y, Zhang W, Chen C, Wang N, Guo Y, Lu Y Tags: Int J Hyg Environ Health Source Type: research

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research