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Scientists develop blueprint for turning stem cells into sensory interneurons
Key takeaways:Just like the real thing.The stem cell –derived interneurons, which play a role in sensations like touch and pain, are indistinguishable from their real-life counterparts in the body.Tomorrow ’s therapies. In addition to potential treatments for injury-related sensation loss, the discovery could lead to new methods for screening drugs for chronic pain.Moving forward. While stem cells from mice were used in the research, scientists are now working to replicate the findings with human cells.Researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have develop...
Source: UCLA Newsroom: Health Sciences - July 19, 2022 Category: Universities & Medical Training Source Type: news

Single mutation leads to big effects in autism-related gene
(NIH/National Institute of Neurological Disorders and Stroke) A new study in Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases. The study was conducted at NIH's National Institute of Neurological Disorders and Stroke (NINDS).
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

The Director of the NIH Lays Out His Vision of the Future of Medical Science
Our world has never witnessed a time of greater promise for improving human health. Many of today’s health advances have stemmed from a long arc of discovery that begins with strong, steady support for basic science. In large part because of fundamental research funded by the National Institutes of Health (NIH), which traces its roots to 1887, Americans are living longer, healthier lives. Life expectancy for a baby born in the U.S. has risen from 47 years in 1900 to more than 78 years today. Among the advances that have helped to make this possible are a 70% decline in the U.S. death rate from cardiovascular disease ...
Source: TIME: Science - October 24, 2019 Category: Science Authors: Dr. Francis S. Collins Tags: Uncategorized Healthcare medicine Source Type: news

Can Fish Oil Help Reading?
Discussion Fats and fatty acids are essential for good human health. Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet. Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature. Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Source: PediatricEducation.org - November 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

NIH awards almost $10 million to UCLA Center for Autism Research and Treatment
The National Institutes of Health, recognizing UCLA ’s leadership in understanding and developing interventions for autism spectrum disorder, has renewed its support of the UCLA Center for Autism Research and Treatment with a five-year, $9.7 million grant.The Autism Center of Excellence grant is directed by Susan Bookheimer, director of the Intellectual and Developmental Disabilities Research Center at UCLA. It supports research projects led by autism experts Mirella Dapretto, Dr. Shafali Jeste, Connie Kasari, Elizabeth Laugeson, Dr. Daniel Geschwind and Dr. Jim McCracken.“This renewed support will allow UCLA to contin...
Source: UCLA Newsroom: Health Sciences - October 13, 2017 Category: Universities & Medical Training Source Type: news

Head injuries can alter hundreds of genes and lead to serious brain diseases, UCLA biologists report
Head injuries can harm hundreds of genes in the brain in a way that increases people ’s risk for a wide range of neurological and psychiatric disorders, UCLA life scientists report.The researchers identified for the first time master genes that they believe control hundreds of other genes which are linked to Alzheimer ’s disease, Parkinson’s disease, post-traumatic stress disorder, stroke, attention deficit hyperactivity disorder, autism, depression, schizophrenia and other disorders.Knowing what the master genes are could give scientists targets for new pharmaceuticals to treat brain diseases. Eventually, scientists...
Source: UCLA Newsroom: Health Sciences - March 6, 2017 Category: Universities & Medical Training Source Type: news

NIH genome sequencing program targets the genomic bases of common, rare disease
The National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases. The National Human Genome Research Institute (NHGRI), part of NIH, today launched the Centers for Common Disease Genomics (CCDG), which will use genome sequencing to explore the genomic contributions to common diseases such as heart disease, diabetes, stroke and autism. NHGRI also announced the next phase of a complementary program, the Centers for Mendelian Genomics (CMG), which will continue investigating the genomic underpinnings of ra...
Source: NHGRI Press Releases - January 14, 2016 Category: Genetics & Stem Cells Source Type: news

$60 million to fund study of genetics underlying common diseases
(Washington University School of Medicine) The McDonnell Genome Institute at Washington University School of Medicine in St. Louis will receive $60 million from the National Institutes of Health to study the genetics of common diseases, such as heart disease, diabetes, stroke, autism and epilepsy.
Source: EurekAlert! - Medicine and Health - January 14, 2016 Category: Global & Universal Source Type: news

Study in mice shows how brain ignores distractions
In a study of mice, scientists discovered that a brain region called the thalamus may be critical for filtering out distractions. The study, published in Nature and partially funded by the National Institutes of Health, paves the way to understanding how defects in the thalamus might underlie symptoms seen in patients with autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 21, 2015 Category: Neurology Source Type: news

Precision medicine is coming, but not anytime soon
President Obama’s announcement of a Precision Medicine Initiative was one of the few items in this year’s State of the Union address to garner bipartisan support. And for good reason. Precision medicine, also known as personalized medicine, offers the promise of health care — from prevention to diagnosis to treatment — based on your unique DNA profile. Who wouldn’t want that? We’ve already had a taste of precision medicine. Relatively low-tech therapies like eyeglasses, orthotic devices, allergy treatments, and blood transfusions have long been personalized for the individual. Genetic analysis o...
Source: New Harvard Health Information - March 26, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Health care personalized health care precision medicine Source Type: news

NIH Funds Robots To Assist People With Disabilities
New research in robotics might help with stroke rehabilitation, guide wheelchairs, and assist children with Autism Spectrum Disorder. Projects investigating co-robotics are the focus of new funding from the National Institutes of Health.
Source: Medical Design Online News - December 9, 2014 Category: Medical Equipment Source Type: news