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Condition: Bleeding
Nutrition: Vitamins
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Total 1031 results found since Jan 2013.
Direct oral anticoagulants versus vitamin K antagonists: Which one is more effective in atrial fibrillation
CONCLUSIONS: Our meta-analysis demonstrates that in patients undergoing bioprosthetic valve surgery and presenting with AF afterward, DOAC and VKA are similar regarding life-threatening and all-cause mortality outcomes, including major bleeding, stroke, and intracranial hemorrhage.PMID:37697799 | DOI:10.1177/02676591231202383
Source: Perfusion - September 12, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Alireza Khodadadiyan Kimia Jazi Hamed Bazrafshan Drissi Helia Bazroodi Mina Mashayekh Erfan Sadeghi Ghazal Gholamabbas Mehdi Bazrafshan Mahdi Rahmanian Source Type: research
Low-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
Korean J Intern Med. 2023 Sep;38(5):583-594. doi: 10.3904/kjim.2023.035. Epub 2023 Sep 1.ABSTRACTIn the last decade, non-vitamin K antagonist oral anticoagulants (NOACs), a new generation of OACs, were introduced to prevent thromboembolism in patients with atrial fibrillation. Although vitamin K-dependent anticoagulants have long been used as OACs, their inherent disadvantage of considerable bleeding complications has limited their use. NOACs demonstrate similar or superior clinical outcomes to those of warfarin. Although strict dose reduction criteria are recommended for NOACs, low-dose NOACs are frequently utilized, espe...
Source: The Korean Journal of Internal Medicine - September 8, 2023 Category: Internal Medicine Authors: Ki Hong Lee Hyung Wook Park Source Type: research
Prediction of major bleeding events in 1381 patients with essential thrombocythemia
Int J Hematol. 2023 Sep 3. doi: 10.1007/s12185-023-03650-7. Online ahead of print.ABSTRACTThe goal of therapy in essential thrombocythemia (ET) is reducing thrombotic risk. No algorithm to predict hemorrhage risk exists. The impact ofanti-platelet, cytoreductive and anticoagulation therapies on risk of major bleeding (MB) was evaluated. MB events were retrospectively analyzed in 1381 ET from 10 European centers. There were 0.286 MB events/person-year. Neither the International Thrombosis Prognostic Score for thrombosis in essential thrombocythemia (IPSET-t) nor the revised IPSET-t (r-IPSET-t) was predictive for hemorrhage-...
Source: International Journal of Hematology - September 3, 2023 Category: Hematology Authors: Ruth Stuckey Jean-Christophe Ianotto Marco Santoro Anna Czy ż Manuel M Perez Encinas Mar ía Teresa Gómez-Casares Maria Soledad Noya Pereira Anna Kulikowska de Na łęcz Aleksandra Go łos Krzysztof Lewandowski Łukasz Szukalski Jes ús M González-Mart Source Type: research
Efficacy and safety of direct oral anticoagulants vs vitamin K antagonists in patients with atrial fibrillation and end-stage renal disease on hemodialysis: A systematic review and meta-analysis
CONCLUSIONS: Among AF patients with ESRD on chronic hemodialysis, the risk of ischemic stroke, ischemic stroke or systemic embolism, minor bleeding, major bleeding, and all-cause mortality is similar in patients treated with DOACs compared to VKAs. Given that the meta-analysis of RCTs on gastrointestinal bleeding did not confirm the results of the meta-analysis of the observational studies, it cannot be concluded that gastrointestinal bleeding is lower among DOAC-treated patients.PROTOCOL REGISTRATION: PROSPERO CRD42023391966.PMID:37648582 | DOI:10.1016/j.ejim.2023.08.020
Source: European Journal of Internal Medicine - August 30, 2023 Category: Internal Medicine Authors: Ioannis Kyriakoulis Anastasia Adamou Iliana Stamatiou David Dimitris Chlorogiannis Ioannis Kardoutsos Despoina Koukousaki George Ntaios Source Type: research
