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Specialty: Drugs & Pharmacology
Condition: Asthma
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Total 142 results found since Jan 2013.
Latex allergy - from discovery to component-resolved diagnosis
Endocr Metab Immune Disord Drug Targets. 2023 Sep 1. doi: 10.2174/1871530323666230901102131. Online ahead of print.ABSTRACTLatex allergy is a hypersensitivity response to natural rubber latex (NRL) proteins or rubber chemicals used in the manufacture of latex products. An accurate diagnosis is the first step in the effective management of individuals with latex allergy, especially in high-risk groups, such as healthcare workers and those affected by spina bifida. Diagnosis is based on the clinical history and an accurate allergological evaluation. In the case of type I IgE-mediated hypersensitivity re-actions, which can ma...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 8, 2023 Category: Drugs & Pharmacology Authors: Teresa Loverre Rossella Casella Andrea Miniello Danilo Di Bona Eustachio Nettis Source Type: research
Updates in the diagnosis and practical management of allergic rhinitis
Expert Rev Clin Pharmacol. 2023 Jun 14. doi: 10.1080/17512433.2023.2225770. Online ahead of print.ABSTRACTINTRODUCTION: Allergic rhinitis (AR) is a widespread disease that can be associated with other conditions, including conjunctivitis, rhinosinusitis, asthma, food allergy and atopic dermatitis. Diagnosis is based on history and documentation of sensitization, such as the production of allergen-specific IgE, preferably using molecular diagnostics. Treatments are based on patient education, non-pharmacological and pharmacological remedies, allergen-specific immunotherapy (AIT), and surgery. Symptomatic treatments mainly c...
Source: Expert Review of Clinical Pharmacology - June 14, 2023 Category: Drugs & Pharmacology Authors: Chiara Trincianti Maria Angela Tosca Giorgio Ciprandi Source Type: research
Exploring Factors Affecting the Occurrence of Hypersensitivity Reactions Induced by Nonionic Iodine Contrast Media
This article is protected by copyright. All rights reserved.PMID:37114401 | DOI:10.1002/jcph.2256
Source: The Journal of Clinical Pharmacology - April 28, 2023 Category: Drugs & Pharmacology Authors: Ryouichi Chatani Sakura Kondo Tadamasa Kamimura Shinya Suzuki Eriko Komatsubara Seiichi Hayashi Masayuki Hashiguchi Hayato Kizaki Shungo Imai Satoko Hori Source Type: research
Continuous ingestion of sodium chloride solution promotes allergen absorption and may exacerbate allergy symptoms on ovalbumin-induced food allergy in mice
In this study, we investigated the effect of continuous ingestion of sodium chloride (NaCl) on allergy symptoms using a mouse model of food allergy. BALB/c mice were divided into four groups of 6-8 animals each. The control-water group (CW) and sensitization-water group (SW) groups were provided free access to water, and the control-1% NaCl group (CS) and sensitization-1% NaCl group (SS) groups were provided a 1% NaCl solution. The SW and SS groups were sensitized with 50 µg ovalbumin (OVA) at 2 timepoints by intraperitoneal injection. After oral administration of OVA, anaphylactic response was measured and blood was coll...
Source: Drug Discoveries and Therapeutics - February 27, 2023 Category: Drugs & Pharmacology Authors: Mamoru Tanaka Rui Lu Hana Kozai Source Type: research
A bibliometric and scientific knowledge map study of the drug therapies for asthma-related study from 1982 to 2021
Conclusion: This study demonstrates the global research hotspots and trends of the research works on drugs for patients with asthma/severe asthma. It can help scholars quickly understand the current status and hotspots of research in this field.
Source: Frontiers in Pharmacology - October 3, 2022 Category: Drugs & Pharmacology Source Type: research
Characterization and pre-clinical assessment of a proposed biosimilar to its originator Omalizumab
Eur J Pharm Sci. 2022 Sep 8:106292. doi: 10.1016/j.ejps.2022.106292. Online ahead of print.ABSTRACTOmalizumab is an anti-IgE monoclonal antibody (mAb) approved for the treatment of moderate-to-severe asthma. Herein, we report physicochemical, biological, pharmacological, and toxicological characteristics of an Omalizumab biosimilar mAb named KA. We show that KA and its originator present only minimum differences. Their charge heterogeneity and primary, secondary structures are similar. The two molecules are comparable regarding in vitro activity, including molecular binding and cell-based inhibition. Pharmacological and to...
Source: European Journal of Pharmaceutical Sciences - September 11, 2022 Category: Drugs & Pharmacology Authors: Yanchao Wang Chen Zheng Chao Zhuang Qiang Fu Baohong Zhang Yanling Bian Nianmin Qi Jianwei Zhu Source Type: research
