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Condition: Asthma
Infectious Disease: Parasitic Diseases

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Total 149 results found since Jan 2013.

The Relationship of Parasite Allergens to Allergic Diseases
AbstractPurpose of ReviewHelminth infections modify the natural history of allergic diseases, by either decreasing or increasing their symptoms. Several helminth components are involved in the increasing of the allergic response and symptoms, overcoming the concomitant immunosuppression of helminthiases. However, the role of individual IgE-binding molecules in this process remains to be defined.Recent FindingsWe updated the list of helminth allergens and IgE-binding molecules, their effects on asthma presentation, and their impact on allergy diagnosis. Data from genetic and epigenetic studies of ascariasis are analyzed. A ...
Source: Current Allergy and Asthma Reports - July 1, 2023 Category: Allergy & Immunology Source Type: research

Interpreting serum tryptase levels in cases of anaphylaxis and concomitant bacterial infection
Mast cells are innate immune cells located near host-environment interfaces, where they can detect diverse stimuli and respond with preformed and de novo synthesized mediators and cytokines. They are involved in host defense against bacterial, viral, or parasitic infection1. By releasing proteases (chymase, tryptase), cytokines/chemokines (TNF- α, CXCL1/KC) and histamine, they promote tissue inflammation, leukocyte recruitment and blood vessel permeability2.
Source: Annals of Allergy, Asthma and Immunology - April 26, 2023 Category: Allergy & Immunology Authors: Luc ía Gonzalez-Torres, Vanesa García-Paz, Leticia Vila Tags: Letters Source Type: research

Unrecognized parasitic infection as a cause of persistent eosinophilia in an inner-city allergy clinic population
Persistent peripheral blood eosinophilia (absolute eosinophil count (AEC)> 500 cells/mL) is frequently a manifestation of a serious medical problem. Nevertheless, previous studies have shown that patients with persistent eosinophilia are often not adequately evaluated for possible underlying causes.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: P. Regula, M. Beronilla, H. Jakubowicz, A. Fizitskaya, D. Ferastraoaru, M. Ramesh, D. Rosenstreich, G. Hudes Tags: Other: Eosinophil Related Conditions/Eosinophilia/Hypereosinophilia Clemens von Pirquet Award – 2 Place Source Type: research

Dupilumab induced hypereosinophilic syndrome (hes)
We describe a case of HES manifesting with altered mental status two months after starting therapy with dupilumab.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: A. Abulhamail, T. Kelbel, J. Lin, L. Funderburk Tags: M028 Source Type: research

From the Pages of AllergyWatch
For this edition of From the Pages of AllergyWatch, I've chosen articles from the May-June 2022 AllergyWatch focusing on food allergies, the theme of this month's Annals. The first article, with comments from Dr. Lee, presents data from South Africa that alpha-gal allergy can be associated with parasites. The next article, with comments from Dr. Hernandez-Trujilio, reports improved outcomes in patients with EoE managed in multidisciplinary clinics. The last article, with comments from Dr. Lee, reports the use of an amino acid-based formula including synbiotics on infants with cow's milk allergy.
Source: Annals of Allergy, Asthma and Immunology - July 14, 2022 Category: Allergy & Immunology Authors: Stanley M. Fineman, Gerald B. Lee, Vivian Hernandez-Trujillo Tags: Special Series Source Type: research

What Are Some Mast Cell Disorders?
Discussion Mast cells (MCs) were first discovered by Paul Ehrlich in 1878. Previously in 1869, Nettleship and Tay described a toddler with chronic urticaria and a brown skin lesion which is believed to be the first reported case of mastocytosis. Urticaria pigmentosa was a term first used by Sangster in 1878, and in 1936 the term mastocytosis was used. “Mast cells first evolved 500 million years ago in Ascidians (sea squirts), providing host innate immunity against bacteria and parasites….MCs gained additional functions regulating inflammation, wound healing, coagulation, adaptive immunity and acute allergic res...
Source: PediatricEducation.org - February 21, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Emerging Functions of IL-33 in Homeostasis and Immunity
Annu Rev Immunol. 2022 Jan 5. doi: 10.1146/annurev-immunol-101320-124243. Online ahead of print.ABSTRACTOur understanding of the functions of the IL-1 superfamily cytokine and damage-associated molecular pattern IL-33 continues to evolve with our understanding of homeostasis and immunity. The early findings that IL-33 is a potent driver of type 2 immune responses promoting parasite expulsion, but also inflammatory diseases like allergy and asthma, have been further supported. Yet, as the importance of a type 2 response in tissue repair and homeostasis has emerged, so has the fundamental importance of IL-33 to these process...
Source: Annual Review of Immunology - January 5, 2022 Category: Allergy & Immunology Authors: Gaelen K Dwyer Louise M D'Cruz H ēth R Turnquist Source Type: research

M036 dobutamine-induced eosinophilia
We present an unusual scenario of eosinophilia in the wake of a routinely used inotrope, dobutamine.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: S. Imam, S. Abbassi, R. Khianey, A. Wolff Source Type: research

M177 polyparasitism in iga deficiency: echinococcus, strongyloides and toxocara as three parasites in  one host
Concomitant infections with several parasites are called polyparasitism. Gastrointestinal infections occur with an increased frequency in patients with IgA deficiency and are commonly related to G lamblia. It is postulated that the lack of secretory IgA in these patients allows for attachment and proliferation of the organism on the intestinal epithelium. Polyparasitism has been reported in patients with HIV/AIDS. This is the first case report of polyparasitism in a patient with primary immunodeficiency.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: M. Dimova, S. Mahapatra, L. Caraballo, V. Dimov Source Type: research

M124 eosinophilia in a 64-year-old male with severe persistent asthma
Eosinophilia is a common finding in patients with allergic disease processes and should prompt further evaluation to rule out certain parasitic infections, hematologic and neoplastic disorders, immunologic disorders, and a variety of other disease processes.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: C. Lomas, F. Hoyte Source Type: research

The effect of infectious agents on the prevalence of allergies
CONCLUSIONS: A history of some forms of either infectious or parasitic diseases has a measurable effect on the risk of developing allergies.PMID:34597894 | DOI:10.1016/j.advms.2021.08.002
Source: Advances in Medical Sciences - October 1, 2021 Category: Biomedical Science Authors: Edyta Krzych-Fa łta Oksana Wojas Filip Raciborski Aneta Tomaszewska Piotr Samel-Kowalik Konrad Furma ńczyk Edward Si ński Ma łgorzata Bednarska Daniel Rabczenko Boles ław Samoliński Source Type: research