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Condition: Thrombocytopenia
Vaccination: Vaccines
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Total 914 results found since Jan 2013.
Long-term efficacy and safety profile of splenectomy for pediatric chronic immune thrombocytopenia
Int J Hematol. 2023 Jan 9. doi: 10.1007/s12185-022-03529-z. Online ahead of print.ABSTRACTThere are few reports of the long-term efficacy of splenectomy in children with immune thrombocytopenia (ITP). In a 33-year period, we performed splenectomies in 23 pediatric patients with ITP at a single institution in Japan. The age at surgery was 5-22 years with a median of 10 years. The follow-up period was 1-141 months with a median of 48 months. Before surgery, we confirmed the presence or absence of the accessory spleen by contrast-enhanced CT scan and we recommended vaccination with pneumococcal vaccine. Four patients underwen...
Source: International Journal of Hematology - January 9, 2023 Category: Hematology Authors: Kyohei Isshiki Makiko Mori Tomoya Irikura Takahiro Ishikawa Mamoru Honda Ryota Kaneko Yuichi Mitani Hirohito Kubota Kohei Fukuoka Koichi Oshima Yuki Arakawa Katsuyoshi Koh Source Type: research
COVID-19 vaccines adverse events: potential molecular mechanisms
Immunol Res. 2023 Jan 6. doi: 10.1007/s12026-023-09357-5. Online ahead of print.ABSTRACTCOVID-19 is an infectious disease caused by a single-stranded RNA (ssRNA) virus, known as SARS-CoV-2. The disease, since its first outbreak in Wuhan, China, in December 2019, has led to a global pandemic. The pharmaceutical industry has developed several vaccines, of different vector technologies, against the virus. Of note, among these vaccines, seven have been fully approved by WHO. However, despite the benefits of COVID-19 vaccination, some rare adverse effects have been reported and have been associated with the use of the vaccines ...
Source: Herpes - January 6, 2023 Category: Infectious Diseases Authors: Malamatenia Lamprinou Athanasios Sachinidis Eleni Stamoula Theofanis Vavilis Georgios Papazisis Source Type: research
Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder
Int J Hematol. 2022 Dec 27. doi: 10.1007/s12185-022-03516-4. Online ahead of print.ABSTRACTVaccine-induced immune thrombotic thrombocytopenia (VITT) is a highly prothrombotic disorder caused by anti-PF4 antibodies that activate platelets and neutrophils, leading to thrombosis. Heparin-induced thrombocytopenia (HIT) is a related anti-PF4 mediated disorder, with similar pathophysiology and clinical manifestations but different triggers (i.e., heparin vs adenoviral vector vaccine). Clinically, both HIT and VITT typically present with thrombocytopenia and thrombosis, although the risk of thrombosis is significantly higher in V...
Source: International Journal of Hematology - December 27, 2022 Category: Hematology Authors: Laura M Venier Bianca Clerici Anna-Lise Bissola Dimpy Modi Stefan D Jevtic Michael Radford Syed Mahamad Ishac Nazy Donald M Arnold Source Type: research
SARS-CoV-2 vaccination: Long-Term Follow-up of Pre-Existing and De Novo Immune Thrombocytopenia (ITP)
Thromb Haemost. 2022 Dec 20. doi: 10.1055/a-2002-1931. Online ahead of print.NO ABSTRACTPMID:36539200 | DOI:10.1055/a-2002-1931
Source: Thrombosis and Haemostasis - December 20, 2022 Category: Hematology Authors: Marina Beltrami Moreira James B Bussel Eun-Ju Lee Source Type: research
Immune thrombocytopenia and COVID-19 vaccination: outcomes and comparisons to pre-pandemic patients
Res Pract Thromb Haemost. 2022 Dec 13:100009. doi: 10.1016/j.rpth.2022.100009. Online ahead of print.NO ABSTRACTPMID:36531670 | PMC:PMC9744687 | DOI:10.1016/j.rpth.2022.100009
Source: Thrombosis and Haemostasis - December 19, 2022 Category: Hematology Authors: Philip Young-Ill Choi Danny Hsu Huyen Anh Tran Chee Wee Tan Anoop Enjeti Vivien Mun Yee Chen Eileen Merriman Agnes S M Yong Jock Simpson Elizabeth Gardiner Nicolas Cherbuin Jennifer Curnow Dominic Pepperell Robert Bird Source Type: research
Thrombosis with thrombocytopenia after vaccination with the ChAdOx1 nCoV-19 vaccine (Oxford-AstraZeneca): implications of gender-specific tissue-factor gene polymorphisms?
Expert Rev Clin Pharmacol. 2022 Dec 3. doi: 10.1080/17512433.2023.2154650. Online ahead of print.NO ABSTRACTPMID:36461814 | DOI:10.1080/17512433.2023.2154650
Source: Pharmacological Reviews - December 3, 2022 Category: Drugs & Pharmacology Authors: Raffaella Mormile Source Type: research
