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Reducing the Risk of Stroke in Patients with Impaired Renal Function: Nutritional Issues
Patients with renal failure have extremely high cardiovascular risk; in dialysis patients the risk of stroke is increased approximately 10-fold over that in the general population. Reasons include not only a high prevalence of traditional risk factors such as diabetes, hypertension and dyslipidemia, but also the accumulation of toxic substances that are eliminated by the kidneys, so have very high levels in patients with renal failure. These include plasma total homocysteine, asymmetric dimethylarginine, thiocyanate, and toxic products of the intestinal microbiome (Gut-Derived Uremic Toxins; GDUT), which include trimethyla...
Source: Journal of Stroke and Cerebrovascular Diseases - November 17, 2020 Category: Neurology Authors: J. David Spence Tags: Review Article Source Type: research

Frailty syndrome: an emerging clinical problem in the everyday management of clinical arrhythmias. The results of the European Heart Rhythm Association survey
In conclusion, the complex clinical condition in frail patients presenting with arrhythmias warrants an integrated multidisciplinary approach both for the management of rhythm disturbances and for the decision on using CIEDs.
Source: Europace - October 10, 2017 Category: Cardiology Source Type: research

Association of chronic disease prevalence and quality of life with suicide-related ideation and suicide attempt among Korean adults.
CONCLUSION: SI was positively associated with selected CDP, such as cardiovascular disease (CVD), stroke, ischemic heart disease (IHD), cancer, diabetes, renal failure, and depression, except hypertension. Subjects with CVD, IHD, renal failure, and depression were found likely to have increased odds for SA as compared to non-SA controls. Lower QoL strongly affected SI and SA. Furthermore, the likelihood of SI increased for depressed and cancer subjects who had low QoL in comparison to subjects with high QoL and without chronic disease. Similarly, statistically, significant interaction was observed between lower QoL and dep...
Source: Indian Journal of Psychiatry - November 2, 2017 Category: Psychiatry Tags: Indian J Psychiatry Source Type: research

Anemia in Heart Failure
Publication date: Available online 8 November 2017 Source:JACC: Heart Failure Author(s): Niels Grote Beverborg, Dirk J. van Veldhuisen, Peter van der Meer One-third of all patients with heart failure have anemia, and its presence is associated with more symptoms, increased rates of hospitalization, and mortality. The etiology of anemia is multifactorial, complex, and varies between patients. The most important factors leading to anemia in heart failure are inadequate erythropoietin production resulting from renal failure, intrinsic bone marrow defects, medication use, and nutritional deficiencies such as iron deficiency. ...
Source: JACC: Heart Failure - November 19, 2017 Category: Cardiology Source Type: research

The kidney and cardiovascular outcome trials
Chronic kidney disease (CKD) affects a substantial minority of people with type 2 diabetes (T2D). Analysis of US National Health and Nutrition Examination Survey (NHANES) datasets from 2007 through 2012 showed Stage 3 or worse disease (estimated glomerular filtration rate [eGFR] <60 mL/min per 1.73 m2) in nearly one in five patients, with increasing age, blood pressure, obesity, and levels of glycemia all associated with higher likelihood of Stage 3 or worse CKD, comparable to findings from surveys from many other areas, which also show micro‐ or macroalbuminuria to be present in one‐sixth to one‐third of diab...
Source: Journal of Diabetes - January 19, 2018 Category: Endocrinology Authors: Zachary Bloomgarden Tags: Editorial Source Type: research

Preoperative prealbumin does not impact outcomes after left ventricular assist device implantation
ConclusionsThis study demonstrates that lower prealbumin levels were not predictive of increased post ‐LVAD morbidity or mortality. Although an established marker of nutritional and inflammatory status, the role of prealbumin in patient selection or prognostication appears limited in LVAD patients.
Source: Journal of Cardiac Surgery - March 31, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Yeahwa Hong, Laura Seese, Gavin Hickey, Michael Mathier, Floyd Thoma, Arman Kilic Tags: ORIGINAL ARTICLE Source Type: research

Potassium
Adv Food Nutr Res. 2021;96:89-121. doi: 10.1016/bs.afnr.2021.02.013. Epub 2021 May 24.ABSTRACTPotassium is an essential nutrient that performs a vital role in cellular functions including maintaining fluid balance and osmolality of cells. Potassium balance is maintained by the kidney and the majority of ingested potassium is excreted in the urine. There is strong evidence of a negative association between dietary potassium and blood pressure, and some evidence (much of it indirect) of negative associations between dietary potassium and cardiovascular disease (particularly stroke and coronary heart disease) and kidney disea...
Source: Advances in Food and Nutrition Research - June 11, 2021 Category: Nutrition Authors: Rachael Mira McLean Nan Xin Wang Source Type: research

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