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Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population ‐based retrospective cohort study
ConclusionsAt a dosage of > 0.5 defined daily dose, short‐term methotrexate might decrease ischemic stroke risk in RA patients, while hydroxychloroquine and sulfasalazine were neutral.
Source: APLAR Journal of Rheumatology - January 1, 2018 Category: Rheumatology Authors: Hong ‐Wei Tam, Chyong‐Mei Chen, Pui‐Ying Leong, Chao‐Hsi Chen, Yuan‐Chao Li, Yu‐Hsun Wang, Li‐Chi Lin, Jeng‐Yuan Chiou, James Cheng‐Chung Wei Tags: Original Article Source Type: research

Potential benefits of biologics on stroke and mortality in patients with rheumatoid arthritis: A nationwide population ‐based cohort study in Taiwan
ConclusionBiologics used in RA patients have been shown to have a beneficial impact on improving clinical outcomes, including decreased risks of death and stroke. The economic burden from costs of biologics may be alleviated by improving outcomes.
Source: International Journal of Rheumatic Diseases - June 24, 2019 Category: Rheumatology Authors: Chao ‐Hsiun Tang, Fun Yu, Ching‐Ya Huang, Der‐Yuan Chen Tags: ORIGINAL ARTICLE Source Type: research

Longitudinal transition trajectory of gouty arthritis and its comorbidities: a population-based study
AbstractThe aim of the study was to investigate the longitudinal transition trajectory of gout and its comorbidities in male patients with gout in different age groups. A total of 3973 male patients who received a new diagnosis of gouty arthritis were identified from the Taiwan Longitudinal Health Insurance Database and divided into two age cohorts (<50 and ≥50 years). Each patient was individually followed from 2000 to 2009 to identify associated comorbidities, namely hypertension, hypercholesterolemia, diabetes mellitus, cardiovascular diseases, and chronic kidney disease. Two outcome measurements of stroke and all...
Source: Rheumatology International - December 20, 2016 Category: Rheumatology Source Type: research

Cardiovascular (CV) Risk after Initiation of Abatacept versus TNF Inhibitors in Rheumatoid Arthritis Patients with and without Baseline CV Disease.
CONCLUSION: In this large cohort of publicly or privately insured patients with RA in the United States, ABA was associated with a 20% reduced risk of CVD versus TNFi. While this observational study is subject to potential residual confounding, our results were consistent in patients with baseline CVD. PMID: 29764964 [PubMed - as supplied by publisher]
Source: J Rheumatol - May 15, 2018 Category: Rheumatology Authors: Jin Y, Kang EH, Brill G, Desai RJ, Kim SC Tags: J Rheumatol Source Type: research

Systemic lupus erythematosus is associated with a higher risk of cervical but not trochanteric hip fracture: A nationwide population‐based study
Conclusion:Patients with SLE are associated with a higher risk for cervical but not trochanteric HF and these two HFs have different risk factors. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - April 16, 2013 Category: Rheumatology Authors: Shu‐Hung Wang, Yu‐Sheng Chang, Chia‐Jen Liu, Chien‐Chih Lai, Wei‐Sheng Chen, Tzeng‐Ji Chen, Shuu‐Jiun Wang Tags: Original Article Source Type: research

Association of Systemic Lupus Erythematosus With a Higher Risk of Cervical but Not Trochanteric Hip Fracture: A Nationwide Population‐Based Study
ConclusionSLE is associated with a higher risk for cervical but not trochanteric HF, and these 2 types of HFs have different risk factors.
Source: Arthritis Care and Research - September 24, 2013 Category: Rheumatology Authors: Shu‐Hung Wang, Yu‐Sheng Chang, Chia‐Jen Liu, Chien‐Chih Lai, Wei‐Sheng Chen, Tzeng‐Ji Chen, Shuu‐Jiun Wang Tags: Systemic Lupus Erythematosus Source Type: research

Disease Outcomes and Care Fragmentation among Patients with Systemic Lupus Erythematosus
Conclusion: In this cross‐site cohort of SLE patients, care fragmentation is associated with increased risk of severe infection and comorbidities. These results suggest that improved health information exchange could positively impact outcomes for SLE patients. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - November 30, 2016 Category: Rheumatology Authors: Theresa L. Walunas, Kathryn L. Jackson, Anh H. Chung, Karen A. Mancera ‐Cuevas, Daniel L. Erickson, Rosalind Ramsey‐Goldman, Abel Kho Tags: Original Article Source Type: research