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Clot Histopathology in Ischemic Stroke with Infective Endocarditis.
CONCLUSION: Detailed morphological and histopathological analysis of EVT-retrieved clots including Gram staining can assist in etiological classification of the clot. Understanding the composition of the clot may be of clinical value in early diagnostics and mapping treatment planning in IE. PMID: 30867075 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - March 13, 2019 Category: Neurology Authors: Bhaskar S, Saab J, Cappelen-Smith C, Killingsworth M, Wu XJ, Cheung A, Manning N, Aouad P, McDougall A, Hodgkinson S, Cordato D Tags: Can J Neurol Sci Source Type: research

Early vs Late Surgery for Patients With Endocarditis and Neurological Injury: A Systematic Review and Meta-analysis
ConclusionsAvailable observational data support delaying surgery by 7-14 days if possible in IE complicated by ischemic stroke and> 21 days in hemorrhagic stroke to decrease perioperative mortality and neurological exacerbation rates. Randomized trials are needed for definitive guidance.RésuméIntroductionLe moment de l’intervention chirurgicale lors d’une endocardite infectieuse (EI) accompagnée d’événements neurologiques reste controversé. Les lignes directrices pertinentes de la Société reposent chacune sur un petit nombre d’études observationnelles. La présente méta-analyse a été conçue pour recher...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Short and long-term outcomes of medically treated isolated left-sided endocarditis: a retrospective study with 5-year longitudinal follow-up
ConclusionNon-operative management of LSIE carries a poor prognosis but may have a role in select cases. Surgical management remains the mainstay for patients with clear surgical indications, including severe regurgitation and PVE. Further prospective analyses are required to better delineate appropriate patient selection for non-surgical management.
Source: Canadian Journal of Cardiology - November 6, 2019 Category: Cardiology Source Type: research

Mitral valve prosthesis choice in patients < 70 years: A systematic review and meta ‐analysis of 20 219 patients
ConclusionMechanical MVR in patients aged less than 70 years is associated with a lower risk of operative mortality as well as a 20% lower risk of long ‐term death and 65% lower risk of mitral valve reoperation but 60% greater risk of bleeding compared with bioMVR in matched or adjusted data.
Source: Journal of Cardiac Surgery - February 27, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Bobby Yanagawa, Jessica Lee, Maral Ouzounian, Akshay Bagai, Asim Cheema, Subodh Verma, Jan O. Friedrich, on behalf of the Canadian Cardiovascular Surgery Meta ‐Analysis Working Group Tags: ORIGINAL ARTICLE Source Type: research