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Cancer: Endometrial Cancer
Drug: Estradiol
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Total 108 results found since Jan 2013.
Compare the Efficacy of Dienogest and the Levonorgestrel Intrauterine System in Women with Adenomyosis
This study enrolled 117 women with symptomatic adenomyosis who visited our hospital from May 1, 2019, to June 30, 2022. Participants were randomized to either the LNG-IUS group (n = 48) or the DNG group (n = 79) in an as-controlled clinical trial for 36 months. Visual analog scale (VAS) scores, uterine volume, endometrial thickness, serum carcinoma antigen 125 level, estradiol, follicle-stimulating hormone, luteinizing hormone, and side effects were assessed to compare the efficacy of LNG-IUS and DNG.FINDINGS: The VAS pain score was significantly decreased in both groups after 3 months of treatment. Three months later, pat...
Source: Clinical Therapeutics - August 20, 2023 Category: Drugs & Pharmacology Authors: Weina Guo Yuchen Lin Sijian Hu Yi Shen Source Type: research
The Application of 18F-FES PET in Clinical Cancer Care: A Systematic Review
CONCLUSIONS: [18F]fluoroestradiol PET is not only a convenient and accurate diagnostic imaging tool for detecting ER-expressing lesions in patients with breast and ovarian cancer but also among patients with uterine cancer. [18F]fluoroestradiol PET is a noninvasive predictive and monitoring tool for treatment response and prognosis.PMID:37482660 | DOI:10.1097/RLU.0000000000004760
Source: Clinical Genitourinary Cancer - July 24, 2023 Category: Cancer & Oncology Authors: Ya-Ting Huang Tom Wei-Wu Chen Li-Yu Chen Ya-Yao Huang Yen-Shen Lu Source Type: research
17- β-estradiol reduces surface PD-L1 expression in estrogen receptor-positive breast cancer but not type 1 endometrial cancer cells
Clin Transl Med. 2023 Jul;13(7):e1330. doi: 10.1002/ctm2.1330.NO ABSTRACTPMID:37448208 | DOI:10.1002/ctm2.1330
Source: Clinical Genitourinary Cancer - July 14, 2023 Category: Cancer & Oncology Authors: Hongzhuo Li Wenyi Gu Penny Jeffery Chen Chen Source Type: research
Trans-ethnic Mendelian randomization study of systemic lupus erythematosus and common female hormone-dependent malignancies
CONCLUSION: This finding suggests a possible causal effect of SLE on the risk of overall endometrial cancer and breast cancer in European and East Asian populations, respectively, by MR analysis, which compensates for inherent limitations of observational research.PMID:37027287 | DOI:10.1097/CM9.0000000000002555
Source: Chinese Medical Journal - April 7, 2023 Category: General Medicine Authors: Tingting Zhu Yantao Ding Xiaoli Xu Liyin Zhang Xuejun Zhang Yong Cui Lu Liu Source Type: research
Protective effect of eicosapentaenoic acid against estradiol valerate-induced endometrial hyperplasia via modulation of NF- κB/HIF-1α/VEGF signaling pathway in rats
CONCLUSIONS: EPA in the used doses provided biochemical and histopathological improvement in EV-induced EH via modulation of NF-κB/HIF-1α/VEGF signaling pathway.PMID:36774993 | DOI:10.1016/j.cbi.2023.110399
Source: Chemico-Biological Interactions - February 12, 2023 Category: Molecular Biology Authors: Walaa Yehia Abdelzaher Mohamed A Ibrahim Marwa Hassan Nashwa Fathy Gamal El-Tahawy Michael Atef Fawzy Heba M Hafez Source Type: research
