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Cancer: Neuroblastoma

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Total 288 results found since Jan 2013.

Single-copy Loss of Rho Guanine Nucleotide Exchange Factor 10 ( < em > arhgef10 < /em > ) Causes Locomotor Abnormalities in Zebrafish Larvae
CONCLUSION: Based on our findings, ARHGEF10 appeared to have a haploinsufficiency effect.PMID:35078560 | DOI:10.3967/bes2022.005
Source: Biomedical and Environmental Sciences : BES - January 26, 2022 Category: Biomedical Science Authors: Yi Zhang Ming Xing An Chen Gong Yang Yang Li Yu Tong Wang Meng Lin Rong Li Chan Tian Source Type: research

< em > YTHDC1 < /em > gene polymorphisms and neuroblastoma susceptibility in Chinese children
In conclusion, our findings highlight the involvement of YTHDC1 gene and its genetic variants in the etiology of NB.PMID:34897032 | DOI:10.18632/aging.203760
Source: Aging - December 13, 2021 Category: Biomedical Science Authors: Yong Li Tongyi Lu Jian Wang Zhenjian Zhuo Lei Miao Zhonghua Yang Jiao Zhang Jiwen Cheng Haixia Zhou Suhong Li Li Li Jing He Aiwu Li Source Type: research

Attenuation of the cytoprotection induced by hypoxic preconditioning upon transfection with BNIP3-siRNA in human neuroblastoma SH-SY5Y cells
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Source: International Journal of Neuroscience - December 13, 2021 Category: Neuroscience Authors: Na Lu Ruiying Bai Bo Liu Weijia Cheng Zekun Wu Source Type: research

Development of ATP13A2-deficient In vitro Model for PARK9 Parkinson’s Disease
Conclusion: ATP13A2-deficient PD model was successfully developed.
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Hypoxia-Inducible Factor-1 α (HIF-1α) Inhibition Impairs Retinoic Acid-Induced Differentiation in SH-SY5Y Neuroblastoma Cells, Leading to Reduced Neurite Length and Diminished Gene Expression Related to Cell Differentiation
Neurochem Res. 2021 Sep 23. doi: 10.1007/s11064-021-03454-3. Online ahead of print.ABSTRACTNeuroblastoma is the most common extracranial solid tumour in childhood, originated from cells of the neural crest during the development of the Sympathetic Nervous System. Retinoids are vitamin-A derived differentiating agents utilised to avoid disease resurgence in high-risk neuroblastoma treatment. Several studies indicate that hypoxia-a common feature of the tumoural environment-is a key player in cell differentiation and proliferation. Hypoxia leads to the accumulation of the hypoxia-inducible factor-1α (HIF-1α). This work aim...
Source: Neurochemical Research - September 24, 2021 Category: Neuroscience Authors: Pedro Ozorio Brum Guilherme Danielski Viola Carolina Saibro-Girardi Camila Tiefensee-Ribeiro Matheus Ozorio Brum Juciano Gasparotto Rachel Krolow Jos é Cláudio Fonseca Moreira Daniel Pens Gelain Source Type: research

Hypoxia-Inducible Factor-1alpha (HIF-1alpha) Inhibition Impairs Retinoic Acid-Induced Differentiation in SH-SY5Y Neuroblastoma Cells, Leading to Reduced Neurite Length and Diminished Gene Expression Related to Cell Differentiation
Neurochem Res. 2021 Sep 23. doi: 10.1007/s11064-021-03454-3. Online ahead of print.ABSTRACTNeuroblastoma is the most common extracranial solid tumour in childhood, originated from cells of the neural crest during the development of the Sympathetic Nervous System. Retinoids are vitamin-A derived differentiating agents utilised to avoid disease resurgence in high-risk neuroblastoma treatment. Several studies indicate that hypoxia-a common feature of the tumoural environment-is a key player in cell differentiation and proliferation. Hypoxia leads to the accumulation of the hypoxia-inducible factor-1α (HIF-1α). This work aim...
Source: Cell Research - September 24, 2021 Category: Cytology Authors: Pedro Ozorio Brum Guilherme Danielski Viola Carolina Saibro-Girardi Camila Tiefensee-Ribeiro Matheus Ozorio Brum Juciano Gasparotto Rachel Krolow Jos é Cláudio Fonseca Moreira Daniel Pens Gelain Source Type: research

Hypoxia-Inducible Factor-1 α (HIF-1α) Inhibition Impairs Retinoic Acid-Induced Differentiation in SH-SY5Y Neuroblastoma Cells, Leading to Reduced Neurite Length and Diminished Gene Expression Related to Cell Differentiation
Neurochem Res. 2021 Sep 23. doi: 10.1007/s11064-021-03454-3. Online ahead of print.ABSTRACTNeuroblastoma is the most common extracranial solid tumour in childhood, originated from cells of the neural crest during the development of the Sympathetic Nervous System. Retinoids are vitamin-A derived differentiating agents utilised to avoid disease resurgence in high-risk neuroblastoma treatment. Several studies indicate that hypoxia-a common feature of the tumoural environment-is a key player in cell differentiation and proliferation. Hypoxia leads to the accumulation of the hypoxia-inducible factor-1α (HIF-1α). This work aim...
Source: Neurochemical Research - September 24, 2021 Category: Neuroscience Authors: Pedro Ozorio Brum Guilherme Danielski Viola Carolina Saibro-Girardi Camila Tiefensee-Ribeiro Matheus Ozorio Brum Juciano Gasparotto Rachel Krolow Jos é Cláudio Fonseca Moreira Daniel Pens Gelain Source Type: research