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Cancer: Lung Cancer

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Total 49680 results found since Jan 2013.

Prognostic nutritional index as a prognostic factor in lung cancer patients receiving chemotherapy: a systematic review and meta-analysis
CONCLUSIONS: We provide preliminary evidence suggesting that lower prognostic nutrition index scores are associated with worse survivability outcomes (progression-free survival and overall survival) in lung cancer patients undergoing chemotherapy. We also show that lower prognostic nutrition index scores correlate with even worse survival outcomes in patients with non-small lung cancer histological subtype of lung cancer. These findings should help clinicians to stratify the risks associated with the chemotherapeutic management of lung cancer patients.PMID:34604956 | DOI:10.26355/eurrev_202109_26783
Source: European Review for Medical and Pharmacological Sciences - October 4, 2021 Category: Drugs & Pharmacology Authors: Q Zhang J Bao Z-Y Zhu M-X Jin Source Type: research

Small cell lung cancer patients treated with immune checkpoint inhibitor: a systematic literature review of treatment efficacy, safety, and quality of life
CONCLUSION: Combining ICIs with chemotherapy enhanced OS and PFS as well as not worsening HRQoL. Among all ICIs, PDL1 inhibitors showed better effectiveness. Future studies should focus on real world settings and more clinical trials using ICIs for not only ES-SCLC but also LS-SCLC.PMID:35575164 | DOI:10.1080/03007995.2022.2078101
Source: Current Medical Research and Opinion - May 16, 2022 Category: Research Authors: Rasika Korde Rajwanth Veluswamy Gisoo Barnes Source Type: research

Time to treatment discontinuation in first-line non-small cell lung carcinoma: an overview
CONCLUSION: Studies reporting TTD are increasing, most notably real-world studies. Given the increasing importance of TTD as an efficacy endpoint, it becomes critical to measure and monitor it in various therapeutic settings such as NSCLC. This is the first study to review all TTD values of drugs used in first-line NSCLC.PMID:36932463 | DOI:10.1080/03007995.2023.2192610
Source: Current Medical Research and Opinion - March 18, 2023 Category: Research Authors: Ruggero Lasala Andrea Zovi Valentina Isgr ò Alessia Romagnoli Felice Musicco Fiorenzo Santoleri Source Type: research

Spontaneous tumor lysis syndrome in patients with solid tumors: a scoping review of the literature
In conclusion, current anecdotal evidence demonstrated that metastatic disease, especially in the liver and lungs, may be associated with STLS-related death compared to no metastatic status. Careful surveillance of high-risk cases within larger studies is essential to identify markers predicting morbidity or mortality.
Source: Medical Oncology - July 11, 2023 Category: Cancer & Oncology Source Type: research

Medical imaging AI market expected to exceed $1.7B by 2027
The medical imaging AI market is projected to produce a 25% growth rate an...Read more on AuntMinnie.comRelated Reading: Interventional x-ray, mobile C-arm markets exceed $4B The road to implementing CT lung cancer screening ECR 2023: The cycle of life -- imaging industry roundup Technology trends at ECR 2023: What can you expect in Vienna? Education is the catalyst to increased adoption of handheld ultrasound
Source: AuntMinnie.com Headlines - July 19, 2023 Category: Radiology Source Type: news

Efficacy and safety of osimertinib for leptomeningeal metastases from EGFR-mutant non-small cell lung cancer: a pooled analysis
ConclusionsOur study highlighted and confirmed the meaningful efficacy and a manageable safety profile of osimertinib for the treatment of LM from EGFR-mutant advanced NSCLC.
Source: European Journal of Medical Research - August 4, 2023 Category: Research Source Type: research

SIgA in various pulmonary diseases
AbstractSecretory immunoglobulin A (SIgA) is one of the most abundant immunoglobulin subtypes among mucosa, which plays an indispensable role in the first-line protection against invading pathogens and antigens. Therefore, the role of respiratory SIgA in respiratory mucosal immune diseases has attracted more and more attention. Although the role of SIgA in intestinal mucosal immunity has been widely studied, the cell types responsible for SIgA and the interactions between cells are still unclear. Here, we conducted a wide search of relevant studies and sorted out the relationship between SIgA and some pulmonary diseases (C...
Source: European Journal of Medical Research - August 27, 2023 Category: Research Source Type: research

Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors
ConclusionIn this study, we have explored luteolin as one of the active components of YQG, and may inhibit the proliferation and migration of A549 cells by decreasing the expression of AR and the regulation of phosphorylation at AR-binding sites.
Source: European Journal of Medical Research - September 16, 2023 Category: Research Source Type: research