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History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas
ConclusionA history of atopy confers a survival benefit in patients with diffuse low-grade glioma. Activation of the BDNF pathway may drive the observed differences.
Source: Journal of Neuro-Oncology - October 29, 2021 Category: Cancer & Oncology Source Type: research

Allergic conditions and risk of glioma and meningioma in the CERENAT case-control study
We examined the association between allergy history and risk of glioma and meningioma in adults using data from the CERENAT (CEREbral tumors: a NATional study) multicenter case-control study carried out in 4 areas in France in 2004 –2010. Participants’ histories of doctor-diagnosed allergic asthma, eczema, rhinitis/hay fever and other allergic conditions were collected at onset through a detailed questionnaire delivered in a face-to-face interview. Conditional logistic regression for matched sets was adjusted for participa nts’ educational level and mobile phone use. A total of 273 glioma cases, 218 meningioma cases ...
Source: Journal of Neuro-Oncology - March 2, 2018 Category: Cancer & Oncology Source Type: research

Allergy is associated with reduced risk of glioma: A meta-analysis.
CONCLUSIONS: Overall or specific allergy is protective against glioma. More prospective cohort studies or molecular laboratory experiments are warranted to elucidate the causation and key mechanism. PMID: 28262389 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - March 1, 2017 Category: Allergy & Immunology Authors: Zhang C, Zhu QX Tags: Allergol Immunopathol (Madr) Source Type: research

Consensus on Allergies and Glioma
Conclusion: A substantial amount of data on the inverse association between atopic conditions and glioma has accumulated, and findings from the GICC study further strengthen the existing evidence that the relationship between atopy and glioma is unlikely to be coincidental. Impact: As the literature approaches a consensus on the impact of allergies in glioma risk, future research can begin to shift focus to what the underlying biologic mechanism behind this association may be, which could, in turn, yield new opportunities for immunotherapy or cancer prevention. Cancer Epidemiol Biomarkers Prev; 25(2); 282–90. ©2016 AACR.
Source: Cancer Epidemiology Biomarkers and Prevention - February 4, 2016 Category: Cancer & Oncology Authors: Amirian, E. S., Zhou, R., Wrensch, M. R., Olson, S. H., Scheurer, M. E., Il'yasova, D., Lachance, D., Armstrong, G. N., McCoy, L. S., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Johansen, C., Houlston, R Tags: Research Articles Source Type: research

Nonallergic comorbidities of atopic eczema: an overview of systematic reviews
Abstract The aims of this overview are to synthesize the current evidence of published systematic reviews (SRs) on nonallergic comorbidities of atopic eczema (AE). EMBASE and MEDLINE were searched for SRs published from inception to November 2012. SRs were selected independently based on predefined inclusion criteria. Methodological quality of SRs included was assessed by two independent reviewers using the Revised Assessment of Multiple Systematic Reviews (R‐AMSTAR) checklist. Nine SRs met all inclusion criteria. Six reviews addressing the association between AE and cancer suggest a decreased risk of glioma, meningioma,...
Source: Allergy - September 21, 2013 Category: Allergy & Immunology Authors: S. Deckert, C. Kopkow, J. Schmitt Tags: Review Article Source Type: research