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Condition: Alcoholism
Cancer: Adenocarcinoma

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Total 227 results found since Jan 2013.

Pancreatic ductal adenocarcinoma with a high expression of alcohol dehydrogenase 1B is associated with less aggressive features and a favorable prognosis
In conclusion, PDAC with high ADH1B expression had less cell proliferation and malignant features, along with higher immune cell infiltration, and had a better prognosis.PMID:37693153 | PMC:PMC10492124
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Kohei Chida Masanori Oshi Arya Mariam Roy Takumi Sato Itaru Endo Kazuaki Takabe Source Type: research

Synthesis of Brominated Lactones Related to Mycalin A: Selective Antiproliferative Activity on Metastatic Melanoma Cells and Inhibition of the Cell Migration
Mar Drugs. 2023 Jun 7;21(6):349. doi: 10.3390/md21060349.ABSTRACTStarting from D-xylonolactone and D-ribonolactone, several five-membered bromolactones, related to the C1-C5 portion of mycalin A lactone, have been synthesized. The bromination of D-ribonolactone with HBr/AcOH, without a subsequent transesterification step, has been studied for the first time, giving us most of the acetylated lactones investigated in the present study. For each compound, where possible, both the C-3 alcohol and the corresponding acetate were prepared. Evaluation of their anti-tumor activity showed that all the acetates possess a good cytotox...
Source: Cancer Control - June 27, 2023 Category: Cancer & Oncology Authors: Domenica Capasso Paola Marino Sonia Di Gaetano Nicola Borbone Monica Terracciano Roberta Trani Caterina Longo Vincenzo Piccialli Source Type: research

A new formulation of Ni/Zn bi-metallic nanocomposite and evaluation of its applications for pollution removal, photocatalytic, electrochemical sensing, and anti-breast cancer
Environ Res. 2023 Jun 21:116462. doi: 10.1016/j.envres.2023.116462. Online ahead of print.ABSTRACTNanocomposites have gained attention due to their variety of applications in different fields. In this research, we have reported a green synthesis of a bi-metallic nanocomposite of nickel and zinc using an aqueous extract of Citrus sinensis in the presence of chitosan (Ni/Zn@orange/chitosan). The nanocomposite was characterized using different techniques. We have examined various applications for Ni/Zn@orange/chitosan. The NPs were manufactured in spherical morphology with a particle range size of 17.34-90.51 nm. Ni/Zn@orange...
Source: Environmental Research - June 23, 2023 Category: Environmental Health Authors: Jia Li Behnam Mahdavi Mehdi Baghayeri Behnaz Rivandi Maryam Lotfi Mohammad Mahdi Zangeneh Akram Zangeneh Reza Tayebee Source Type: research

Diet and lifestyle in relation to small intestinal cancer risk: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)
CONCLUSION: These exploratory analyses found limited evidence for a role of modifiable risk factors in SIC aetiology. However, sample size was limited, particularly for histologic subtypes; therefore, larger studies are needed to delineate these associations and robustly identify risk factors for SIC.PMID:37330982 | DOI:10.1007/s10552-023-01731-w
Source: Cancer Control - June 18, 2023 Category: Cancer & Oncology Authors: Zeynep Ersoy Guller Rhea N Harewood Elisabete Weiderpass Inge Huybrechts Mazda Jenab Jos é María Huerta Maria-Jose S ánchez Paula Jakszyn Pilar Amiano Eva Ardanaz Claudia Agnoli Rosario Tumino Domenico Palli Guri Skeie Jonas Manjer Keren Papier Anne Tj Source Type: research

Clinicopathological Characteristics and Mutational Landscape of < em > APC < /em > , < em > HOXB13, < /em > and < em > KRAS < /em > among Rwandan Patients with Colorectal Cancer
In conclusion, here we contribute new genetic variation data and provide clinicopathological information pertinent to CRC in Rwanda.PMID:37232746 | PMC:PMC10217012 | DOI:10.3390/cimb45050277
Source: Current Issues in Molecular Biology - May 26, 2023 Category: Molecular Biology Authors: Felix Manirakiza Eric Rutaganda Hidetaka Yamada Yuji Iwashita Belson Rugwizangoga Benoit Seminega Vincent Dusabejambo Gervais Ntakirutimana Deogratias Ruhangaza Annette Uwineza Kazuya Shinmura Haruhiko Sugimura Source Type: research