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Specialty: Neurology
Cancer: Brain Cancers

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Total 371 results found since Jan 2013.

Diindolylmethane Ameliorates Ischemic Stroke-Induced Brain Injury by Peripheral and Central Mechanisms
CONCLUSION: This inhibition of platelet aggregation, platelet mediated oxidative stress, and inflammation, improved blood flow, and reduced neurological deficits, brain infarction, BBB leakage, brain water content, and histopathological abnormalities indicate the preservation of brain structural integrity. Therefore, these findings conclude that DIM exhibits neuroprotection by inhibiting platelet aggregation. Thus, the present study provided preclinical evidence of DIM neuroprotection against ischemic stroke.PMID:36397630 | DOI:10.2174/1567202620666221116161128
Source: Current Neurovascular Research - November 18, 2022 Category: Neurology Authors: Ramakrishna Kakarla Sushil Kumar Singh Sairam Krishnamurthy Source Type: research

Mesenchymal Stem Cells Prevent Hydrocephalus After Severe Intraventricular Hemorrhage Basic Sciences
Conclusions— Intraventricular transplantation of umbilical cord blood-derived mesenchymal stem cells significantly attenuated the posthemorrhagic hydrocephalus and brain injury after IVH. This neuroprotective mechanism appears to be mediated by the anti-inflammatory effects of these cells.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Ahn, S. Y., Chang, Y. S., Sung, D. K., Sung, S. I., Yoo, H. S., Lee, J. H., Oh, W. I., Park, W. S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Is Achondroplasia Linked to Stroke? (P6.265)
CONCLUSIONS:This case shows an interesting correlation between achondroplasia and carney complex related myxomas that has not been described in literature before. Achondroplasia is an autosomal dominant mutation in FGFR3 gene on chromosome 4P. Mutaions in carney complex are also described to be autosomal dominant mostly involving chromosome 17q23-q24 . There has been no clear pathogenesis described pertaining this correlation yet but more genetics have to be explored.Study Supported by:Disclosure: Dr. Kaur has nothing to disclose. Dr. Mittal has nothing to disclose. Dr. Hosley has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kaur, H., Mittal, S., Hosley, C. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Telmisartan Ameliorates Inflammatory Responses in SHR-SR After tMCAO
We examined the effects of telmisartan on inflammatory responses of monocyte chemotactic protein-1, tumor necrosis factor-α, and ionized calcium-binding adapter molecule 1 in the brain of spontaneously hypertensive rat stroke-resistant (SHR-SR) after transient middle cerebral artery occlusion (tMCAO).
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2014 Category: Neurology Authors: Kota Sato, Toru Yamashita, Tomoko Kurata, Yusuke Fukui, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Source Type: research

Brain and Spinal Tumors
Brain and spinal cord tumors information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research

Intratumoral Hemorrhage in a Patient with Malignant Meningioma under Anticoagulant Therapy
We report the case of an elderly woman with malignant meningioma and atrial fibrillation who started taking anticoagulants after an ischemic stroke and subsequently developed intratumoral hemorrhage. Further studies are required to confirm whether a particular anticoagulant agent is suitable for patients with brain tumor and atrial fibrillation.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2015 Category: Neurology Authors: Yasuyuki Ito, Makoto Nakajima, Mari Watari, Tetsuro Sakamoto, Yoichiro Hashimoto, Seiji Tajiri, Akira Takada, Yukio Ando Tags: Case Report Source Type: research

Strengthening the immune system’s fight against brain cancer
When cancer strikes, it may be possible for patients to fight back with their own defenses, using a strategy known as immunotherapy. According to a new study published in Nature, researchers have found a way to enhance the effects of this therapeutic approach in glioblastoma, a deadly type of brain cancer, and possibly improve patient outcomes. The research was funded by the National Institute of Neurological Disorders and Stroke (NINDS) as well as the National Cancer Institute (NCI), which are part of the National Institutes of Health.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - March 18, 2015 Category: Neurology Source Type: news

Diagnostic and Management Challenges in Patients with Left Atrial Myxoma (P1.229)
Conclusions:Cardiac myxomas are rare tumors, mostly arising from the left atrium that may cause ischemic or hemorrhagic strokes, intracranial aneurysms, or myxomatous metastases.Disclosure: Dr. Orjuela has nothing to disclose. Dr. McGinley has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Prabhu has nothing to disclose. Dr. Bakhos has nothing to disclose. Dr. Biller has received personal compensation in an editorial capacity for the Journal of Stroke and Cerebrovascular Diseases, Frontier in Neurology and Up-To-Date.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Orjuela, K., McGinley, M., Sweis, R., Prabhu, V., Bakhos, M., Biller, J. Tags: Cardiac Mechanisms and Complications of Stroke Source Type: research

Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome
Ramnath Santosh Ramanathan, Gayathri Sreedher, Konark Malhotra, Zain Guduru, Deeksha Agarwal, Mary Flaherty, Timothy Leichliter, Sandeep RanaAnnals of Indian Academy of Neurology 2016 19(3):399-401Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right te...
Source: Annals of Indian Academy of Neurology - July 24, 2016 Category: Neurology Authors: Ramnath Santosh Ramanathan Gayathri Sreedher Konark Malhotra Zain Guduru Deeksha Agarwal Mary Flaherty Timothy Leichliter Sandeep Rana Source Type: research

Stroke like migraine attacks after radiation therapy (SMART) syndrome a case series of three patients (P6.179)
Conclusions:Our patients represent the first case series of SMART syndrome in a single institution. Our cases share similarities to the prior reports in the literature and highlights the clinical and MRI triad of acute onset headaches, neurological deficits and MRI findings of transient contrast enhancement of the cortex with white matter sparing in a previous radiation field.Disclosure: Dr. rauf has nothing to disclose. Dr. Boulter has nothing to disclose. Dr. Imitola has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rauf, Y., Boulter, D., Imitola, J. Tags: Neurologic Complications of Cancer Source Type: research

Calcified Cerebral Embolism Due to a Calcified Amorphous Tumor
A 59-year-old man developed brain embolism in the frontal and parietal cortex. Brain CT showed a high-density spot in the upper branch of the left middle cerebral artery, indicating calcified cerebral embolism. Calcified amorphous tumor attached to the mitral valve was identified as the cause of embolism. After surgical resection, anticoagulation was started and recurrent stroke did not occur.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2018 Category: Neurology Authors: Yoichiro Nagao, Makoto Nakajima, Tomoo Hirahara, Kuniyasu Wada, Tadashi Terasaki, Michiko Nagamine, Yukio Ando Tags: Case Studies Source Type: research