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Cancer: Squamous Cell Carcinoma
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Total 19037 results found since Jan 2013.
The Use of Salivary Levels of Matrix Metalloproteinases as an Adjuvant Method in the Early Diagnosis of Oral Squamous Cell Carcinoma: A Narrative Literature Review
Curr Issues Mol Biol. 2022 Dec 12;44(12):6306-6322. doi: 10.3390/cimb44120430.ABSTRACTOral squamous cell carcinoma (OSCC) is an aggressive malignancy with increased mortality, in which the early diagnosis is the most important step in increasing patients' survival rate. Extensive research has evaluated the role of saliva as a source of diagnostic biomarkers, among which matrix metalloproteinases (MMPs) have shown a valuable potential for detecting even early stages of OSCC. The aim of this review was to present recent clinical data regarding the significance of salivary MMPs in the detection of early malignant transformati...
Source: Current Issues in Molecular Biology - December 22, 2022 Category: Molecular Biology Authors: Monica Monea Anca Maria Pop Source Type: research
Deciphering cervical cancer-associated biomarkers by integrated multi-omics approach
CONCLUSION: Through detailed in silico methodology, we identified 6 hub genes, including MCM4, NUSAP1, CDCA5, CDC45, DTL, and CDT1, which are likely to be associated with CESC development and diagnosis.PMID:36628250 | PMC:PMC9827308
Source: Cell Research - January 11, 2023 Category: Cytology Authors: Xuhong Li Mostafa A Abdel-Maksoud Iqra Iqbal Ayman Mubarak Mohamed A Farrag Muhammad Haris Sumaiah Alghamdi Qurat Ul Ain Sally Almekhlafi Source Type: research
The Use of Salivary Levels of Matrix Metalloproteinases as an Adjuvant Method in the Early Diagnosis of Oral Squamous Cell Carcinoma: A Narrative Literature Review
Curr Issues Mol Biol. 2022 Dec 12;44(12):6306-6322. doi: 10.3390/cimb44120430.ABSTRACTOral squamous cell carcinoma (OSCC) is an aggressive malignancy with increased mortality, in which the early diagnosis is the most important step in increasing patients' survival rate. Extensive research has evaluated the role of saliva as a source of diagnostic biomarkers, among which matrix metalloproteinases (MMPs) have shown a valuable potential for detecting even early stages of OSCC. The aim of this review was to present recent clinical data regarding the significance of salivary MMPs in the detection of early malignant transformati...
Source: Current Issues in Molecular Biology - December 22, 2022 Category: Molecular Biology Authors: Monica Monea Anca Maria Pop Source Type: research
Oral Microflora and Its Potential Carcinogenic Effect on Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
Cureus. 2023 Jan 9;15(1):e33560. doi: 10.7759/cureus.33560. eCollection 2023 Jan.ABSTRACTThe oral cavity has the second largest and most diverse microflora. A wide variety of bacteria, viruses, and fungi are present in the oral cavity. A significant number of studies have shown the important role of oral microflora in the initiation and pathogenesis of oral squamous cell carcinoma (OSCC). Microorganisms like Staphylococcus, Streptococcus, Neisseria, Prevotella, Fusobacterium, Porphyromonas, Herpes Simplex Virus I (HSV-1), Epstein-Barr Virus (EBV), Human Papilloma Virus (HPV), Candida plays an important role in OSCC. Increa...
Source: Herpes - February 13, 2023 Category: Infectious Diseases Authors: Mudiyayirakkani Muthusamy Pratibha Ramani Reshma Poothakulath Krishnan Hemashree K Gheena Sukumaran Abilasha Ramasubramanian Source Type: research
A Systematic Review and Meta-Analysis Assessing the Role of Oral Health as a Risk Factor in Oral Cancer
Cureus. 2023 May 31;15(5):e39786. doi: 10.7759/cureus.39786. eCollection 2023 May.ABSTRACTOral squamous cell carcinoma is the leading type of cancer in Southeast Asian countries and many parts of the world. Many factors increase the risk of oral cancer, like tobacco, betel nuts, alcohol consumption, sharp teeth, infections, and other factors. Oral health-related issues have been reported in many studies of oral cancer, but there is a need to understand the role of the same as a risk factor. The systematic review and meta-analysis were conducted to assess the role of oral health as a risk factor in oral cancer. The populati...
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Amit V Mahuli Vidya Sagar Amit Kumar Simpy A Mahuli Anit Kujur Source Type: research
Six polymorphisms in the lncRNA H19 gene and the risk of cancer: a systematic review and meta-analysis
CONCLUSION: H19 rs2839698 and rs3024270 were closely associated with overall cancer risk. H19 rs2107425 was related to lower cancer risk among Caucasians, while the rs2839698 was related to increased cancer risk among Asians. Our results supported that H19 SNPs were significantly correlated with cancer risk.PMID:37480014 | PMC:PMC10362596 | DOI:10.1186/s12885-023-11164-y
Source: Cancer Control - July 21, 2023 Category: Cancer & Oncology Authors: Maoquan Yang Mingwei Zhang Qiong Wang Xiaojing Guo Peizhen Geng Jinhua Gu Wansheng Ji Li Zhang Source Type: research
