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Total 153 results found since Jan 2013.

Recurrent embolic strokes due to antiphospholipid syndrome and non-bacterial thrombotic endocarditis in a patient with basal cell carcinoma
CONCLUSION: Outside of SLE and antiphospholipid syndrome, NBTE is a rare and underdiagnosed disease associated with thromboembolic events. Adequate anticoagulation is a cornerstone of its treatment. Anticoagulation management during perioperative care and valve surgery deserves specific attention and helps to protect the patient from embolic complications. In the case of stroke and thromboembolic events of unclear cause or suspected NBTE, echocardiography and thrombophilia assessments including an immunological workup are recommended.PMID:37170311 | PMC:PMC10176810 | DOI:10.1186/s13019-023-02266-6
Source: Hand Surgery - May 11, 2023 Category: Surgery Authors: Julianna Svantner Luc Lavanchy Ania Labouch ère Source Type: research

Anti-inflammatory drug may help prevent heart attacks
Conclusion This well-conducted study shows promising signs that canakinumab may reduce the risk of future heart attacks and other cardiovascular events in people who've had them in the past. But before any changes are made to the current licensing of this drug, further research is needed to confirm the beneficial effects and the optimal dose. Most importantly, researchers will need to focus on the observation that the drug lowered white blood cell counts and increased the risk of fatal infection. They estimated around 1 in every 300 people taking canakinumab would die of a fatal infection. This number, while low, is sti...
Source: NHS News Feed - August 30, 2017 Category: Consumer Health News Tags: Heart/lungs Source Type: news

Partial and complete retirement due to ill-health among mature age Australians
Conclusions: To reduce early retirement due to ill-health, health practitioners, governments and employers should address targeted health problems, particularly in areas outside capital cities.
Source: Public Health - February 20, 2013 Category: Global & Universal Authors: S.W. Pit, R. Shrestha, D. Schofield, M. Passey Tags: Original Research Source Type: research

Little proof sunbathing cuts heart attack risk
Conclusion This laboratory study has found that UVA exposure caused a short-term drop in blood pressure and an increase in blood flow. The researchers believe that this is as a result of nitric oxide being released from the skin into the bloodstream. However, the researchers' assertion that this study "has significant public health implications" is open to question. Such a bold statement should probably only be made if further controlled studies are carried out to see whether UVA exposure can reduce the risk of death as a result of cardiovascular disease, and whether UVA exposure can reduce blood pressure in peo...
Source: NHS News Feed - January 21, 2014 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Cancer Source Type: news

Exercise may cut breast cancer risk, study finds
ConclusionThis large study has shown that increased exercise is associated with a reduced risk of breast cancer for postmenopausal women. Strengths of the study include the large number of women and that self-reports of breast cancer were verified by a pathology report in 94% of cases.However, as the authors point out, a limitation of this study is that it was conducted on a group of teachers who were mainly of a healthy weight. This means the results may not be applicable to women of a different weight with different occupations, including more or less sedentary jobs.The study also relied on self-reported exercise levels,...
Source: NHS News Feed - August 11, 2014 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

Corrections Corrections
Traylor M, Farrall M, Holliday EG, et al, on behalf of the International Stroke Genetics Consortium. Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol 2012; 11: 951–62—In this Article, the last sentence of the VISP section in the acknowledgments section should have been “Control data for comparison with VISP cases were obtained through the database of genotypes and phenotypes (dbGAP) High Density SNP Association Analysis of Melanoma: Case-Control and Outcomes Investigation (phs000187.v1.p1).
Source: Lancet Neurology - July 13, 2015 Category: Neurology Tags: Corrections Source Type: research

Risk of solid cancer, cardiovascular disease, anaphylaxis, osteoporosis and fractures in patients with systemic mastocytosis: A nationwide population‐based study
This article is protected by copyright. All rights reserved.
Source: American Journal of Hematology - July 17, 2016 Category: Hematology Authors: Sigurd Broesby‐Olsen, Dóra Körmendiné Farkas, Hanne Vestergaard, Anne Pernille Hermann, Michael Boe Møller, Charlotte Gotthard Mortz, Thomas Kielsgaard Kristensen, Carsten Bindslev‐Jensen, Henrik Toft Sørensen, Henrik Frederiksen Tags: Research Article Source Type: research

7 Foot Problems That Can Be Serious
If you want to know the state of your health, try looking down. “There’s no question it’s extremely important that people pay attention to their feet,” says Terry Philbin, D.O., spokesperson for the American Academy of Orthopedic Surgeons (AAOS) and a foot and ankle specialist at the Orthopedic Foot and Ankle Center in Westerville, Ohio. The condition of your feet can give you clues to a host of medical issues, such as diabetes, arthritis, and even heart disease. Read on to find out what to look for and what it may mean. 1. Pain “There’s no pain that should be ignored,” says Jane ...
Source: Healthy Living - The Huffington Post - November 12, 2016 Category: Consumer Health News Source Type: news

Blood Cholesterol and Outcome of Patients with Cancer under Regular Cardiological Surveillance
Curr Oncol. 2021 Feb 12;28(1):863-872. doi: 10.3390/curroncol28010085.ABSTRACTCardiovascular (CV) diseases and cancer share several similarities, including common risk factors. In the present investigation we assessed the relationship between cholesterol levels and mortality in a cardiooncological collective. In total, 551 patients receiving anticancer treatment were followed over a median of 41 (95% CI 40, 43) months and underwent regular cardiological surveillance. A total of 140 patients (25.4%) died during this period. Concomitant cardiac diseases were more common in patients who deceased (53 (37.9%) vs. 67 (16.3%), p ...
Source: Current Oncology - February 22, 2021 Category: Cancer & Oncology Authors: Anna Lena Hohneck Stephanie Rosenkaimer Ralf-Dieter Hofheinz Ibrahim Akin Martin Borggrefe Stefan Gerhards Source Type: research

Clinical Symptoms, Laboratory Parameters and Long-Term Follow-up in a National DADA2 Cohort
In conclusion, this cohort describes the clinical, genetic and laboratory findings of 29 Dutch DADA2 patients. We describe the occurrence of HLH as a life-threatening disease complication and report a relatively high incidence of malignancies and mortality.
Source: Journal of Clinical Immunology - June 5, 2023 Category: Allergy & Immunology Source Type: research

Distinct cardiovascular and cancer burdens associated with social position, work environment and unemployment: a cross-sectional and retrospective study in a large population-based French cohort
Conclusions Social position, work environment and unemployment are associated with distinct cardiovascular and cancerous diseases that could add up during lifetime, they should therefore be considered all together in any preventive strategy.
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Sanchez Rico, M., Plessz, M., Airagnes, G., Ribet, C., Hoertel, N., Goldberg, M., Zins, M., Meneton, P. Tags: Open access, Epidemiology Source Type: research

Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver.
Abstract High circulating cholesterol is associated with hypercholesterolemia, atherosclerosis, and stroke. However, the relation between cholesterol and tumorigenesis/metastasis is controversial. The proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates low-density lipoprotein cholesterol homeostasis by targeting the low-density lipoprotein receptor (LDLR) for degradation. PCSK9 is mostly expressed in liver, which is one of the most common sites for metastatic disease. To reveal the function of PCSK9 and also evaluate the impact of cholesterol in liver metastasis development, B16F1 melanoma cells were i...
Source: Neoplasia - December 1, 2012 Category: Cancer & Oncology Authors: Sun X, Essalmani R, Day R, Khatib AM, Seidah NG, Prat A Tags: Neoplasia Source Type: research

Treatment Of Panx1-Related Diseases Could Involve Food Dye
The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physiology. Panx1, which is involved in signaling events leading to inflammation and cell death, has been implicated in such diverse diseases as Crohn's, AIDS, melanoma, epilepsy, spinal cord injury, and stroke, among others. Thus, there is a demand for the development of pharmacological tools to inhibit Panx1...
Source: Health News from Medical News Today - May 1, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Sun Exposure Could Benefit Health And Prolong Life
Exposing skin to sunlight may help to reduce blood pressure, cut the risk of heart attack and stroke - and even prolong life, a study suggests. Researchers have shown that when our skin is exposed to the sun's rays, a compound is released in our blood vessels that helps lower blood pressure. The findings suggest that exposure to sunlight improves health overall, because the benefits of reducing blood pressure far outweigh the risk of developing skin cancer. The study has been carried out by the University of Edinburgh...
Source: Health News from Medical News Today - May 10, 2013 Category: Consumer Health News Tags: Hypertension Source Type: news