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Clinical features and outcomes of opsoclonus myoclonus ataxia syndrome
CONCLUSIONS: Acute lymphoblastic leukemia, vaccines against hepatitis A and meningococci can be included among antecedent factors in OMAS. Among clinical symptoms, speech problems might point to the likelihood of an underlying neoplasm in OMAS. Intravenous immunoglobulin and steroids may be chosen for initial treatment while rituximab can increase the chance of recovery in case of persistent or recurrent symptoms. The presence of relapse was associated with poor outcome.PMID:36155293 | DOI:10.1016/j.ejpn.2022.09.002
Source: European Journal of Paediatric Neurology - September 26, 2022 Category: Neurology Authors: Mira ç Yıldırım İbrahim Öncel Ömer Bektaş Gizem Tanal ı S üleyman Şahin Tezer Kutluk Serap Teber Banu Anlar Source Type: research

Vaccines for measles, mumps, rubella, and varicella in children
CONCLUSIONS: Existing evidence on the safety and effectiveness of MMR/MMRV vaccines support their use for mass immunisation. Campaigns aimed at global eradication should assess epidemiological and socioeconomic situations of the countries as well as the capacity to achieve high vaccination coverage. More evidence is needed to assess whether the protective effect of MMR/MMRV could wane with time since immunisation.PMID:34806766 | DOI:10.1002/14651858.CD004407.pub5
Source: Cochrane Database of Systematic Reviews - November 22, 2021 Category: General Medicine Authors: Carlo Di Pietrantonj Alessandro Rivetti Pasquale Marchione Maria Grazia Debalini Vittorio Demicheli Source Type: research

Vaccines for measles, mumps, rubella, and varicella in children.
CONCLUSIONS: Existing evidence on the safety and effectiveness of MMR/MMRV vaccines support their use for mass immunisation. Campaigns aimed at global eradication should assess epidemiological and socioeconomic situations of the countries as well as the capacity to achieve high vaccination coverage. More evidence is needed to assess whether the protective effect of MMR/MMRV could wane with time since immunisation. PMID: 32309885 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - April 19, 2020 Category: General Medicine Authors: Di Pietrantonj C, Rivetti A, Marchione P, Debalini MG, Demicheli V Tags: Cochrane Database Syst Rev Source Type: research

B Cell Reconstitution and Influencing Factors After Hematopoietic Stem Cell Transplantation in Children
Nicolaas G. van der Maas, Dagmar Berghuis, Mirjam van der Burg and Arjan C. Lankester* Willem-Alexander Children's Hospital, Department of Pediatrics and Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, Netherlands B cell reconstitution after hematopoietic stem cell transplantation (HSCT) is variable and influenced by different patient, donor, and treatment related factors. In this review we describe B cell reconstitution after pediatric allogeneic HST, including the kinetics of reconstitution of the different B cell subsets and the development of the B cell repertoire, and d...
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research

Vaccines for measles, mumps and rubella in children
Abstract BackgroundMumps, measles and rubella (MMR) are serious diseases that can lead to potentially fatal illness, disability and death. However, public debate over the safety of the trivalent MMR vaccine and the resultant drop in vaccination coverage in several countries persists, despite its almost universal use and accepted effectiveness. ObjectivesTo assess the effectiveness and adverse effects associated with the MMR vaccine in children up to 15 years of age. Search methodsFor this update we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 2), which includes the...
Source: Evidence-Based Child Health: A Cochrane Review Journal - November 20, 2013 Category: Pediatrics Authors: Vittorio Demicheli, Alessandro Rivetti, Maria Grazia Debalini, Carlo Di Pietrantonj Tags: Intervention Review Source Type: research