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Cancer progression by the okadaic acid class of tumor promoters and endogenous protein inhibitors of PP2A, SET and CIP2A
ConclusionThis review establishes the concept that inhibition of PP2A activity is a common mechanism of human cancer progression and activation of PP2A activity leads to effective anticancer therapy.
Source: Journal of Cancer Research and Clinical Oncology - July 28, 2023 Category: Cancer & Oncology Source Type: research

Natural Anticancer Agents: Their Therapeutic Potential, Challenges,s and Promising Outcomes
Curr Med Chem. 2023 May 2. doi: 10.2174/0929867330666230502113150. Online ahead of print.ABSTRACTCancer, the second leading cause of death worldwide, is a major health problem. Chemotherapy, radiation therapy and surgery are current treatments for cancer. Most anticancer drugs have severe toxic effects and are required to be administered in cycles to reduce toxicity and prevent resistance. Plant-based drugs have shown a potential for treatment of cancer, and various plant secondary metabolites have shown promising antitumor activity against several cancer cell lines, such as leukemia, colon cancer, prostate cancer, breast ...
Source: Current Medicinal Chemistry - May 4, 2023 Category: Chemistry Authors: Savita Tauro Bharat Dhokchawle Popat Mohite Deepali Nahar Sahaya Nadar Evans Coutinho Source Type: research

Cancer progression by the okadaic acid class of tumor promoters and endogenous protein inhibitors of PP2A, SET and CIP2A
CONCLUSION: This review establishes the concept that inhibition of PP2A activity is a common mechanism of human cancer progression and activation of PP2A activity leads to effective anticancer therapy.PMID:37097392 | DOI:10.1007/s00432-023-04800-4
Source: Clinical Colorectal Cancer - April 25, 2023 Category: Cancer & Oncology Authors: Hirota Fujiki Eisaburo Sueoka Tatsuro Watanabe Atsumasa Komori Masami Suganuma Source Type: research

Assessment of metabolic syndrome parameters in pediatric acute lymphoblastic leukemia survivors
CONCLUSION: Disorders of the metabolic parameter were found to be more common among acute lymphoblastic leukemia survivors than among healthy controls.PMID:36861687 | DOI:10.4103/ijc.IJC_1110_20
Source: Cancer Control - March 2, 2023 Category: Cancer & Oncology Authors: Omer Kartal Orhan G ürsel Source Type: research

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