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Total 473 results found since Jan 2013.
Therapeutic benefits of prophetic medicine remedies in treating hematological diseases (A review article)
Am J Blood Res. 2023 Aug 15;13(4):130-142. eCollection 2023.ABSTRACTHematological disorders are common medical ailments constituting an important cause of morbidity and mortality worldwide, which may be managed efficiently using different prophetic medicine remedies as adjuvants to current therapeutics. Prophetic medicine includes the body of knowledge about medicine that has been derived from the deeds, customs (sunnah), ahadith (sayings), actions, and agreements of Prophet Muhammad, peace be upon him. This review article aims at exploring the magnitude of therapeutic benefits of prophetic medicine remedies as adjuvant tr...
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Ghazi H Mogharbel Ahmad S Badawi Amal Yaseen Zaman Mehrevan M Abd Elmoniem Ibrahim M Abdel-Rahman Mariam Eid Alenazi Fareed Akbar Shah Mohamed Abdelnaem Aly Syed Nazar Imam Nusaybah Eid Alenazi Salah Mohamed El Sayed Source Type: research
Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections
DiscussionThe identified relationships between some of them and virus-induced alteration of immune functions are new and have not been found earlier, e.g., receptors for autocrine motility factor, insulin, prolactin, angiotensin II, and immunoglobulin epsilon. Modulation of the identified receptors can be investigated as one of therapeutic strategies for the treatment of severe viral infections.
Source: Frontiers in Immunology - September 19, 2023 Category: Allergy & Immunology Source Type: research
Retrospective Case-Control Study of REGEN-COV (casirivimab and imdevimab) Therapy for Patients with COVID-19 and Cancer Using the United States MarketScan ® Database
Conclusion Patients with cancer treated with REGEN-COV experienced a decreased risk for hospitalization, hospitalization duration, and total COVID-19-related costs. Patients with cancer were at a higher risk of being hospitalized for COVID-19 than were those without cancer. The use of neutralizing antibody therapy may reduce the risk of severe COVID-19 infection for patients with cancer with an otherwise high risk. Future replication studies should be conducted using other databases that include Medicaid users and other insured persons for comparison and validation.PMID:37666220 | DOI:10.1159/000533614
Source: Oncology - September 4, 2023 Category: Cancer & Oncology Authors: Kazue Takemoto Source Type: research
Living with a blood cancer in later life: The complex challenges and related support needs of adults aged 75 and older
This study investigated the challenges and support needs of adults aged 75 and older during and after treatment for a blood cancer to aid targeted supportive resource development.METHODS: Adults aged 75 and older with a blood cancer participated in in-depth, semi-structured interviews about challenges and unmet support needs. Participants recruited through The Leukemia & Lymphoma Society were (1) in treatment or previously in treatment for a blood cancer at age 75 or older and (2) living in the United States or its territories. A thematic analysis was conducted with findings compared between 2 groups: (1) chronic -livi...
Source: Palliative and Supportive Care - August 22, 2023 Category: Palliative Care Authors: Naomi D Parker Easton N Wollney Carma L Bylund Tithi B Amin M Devyn Mullis Diliara Bagautdinova Maria Sae-Hau Elisa S Weiss Lyndsey A Thomas Carla L Fisher Source Type: research
Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review
Bioorg Chem. 2023 May 11;138:106600. doi: 10.1016/j.bioorg.2023.106600. Online ahead of print.ABSTRACTGuanidines are fascinating small nitrogen-rich organic compounds, which have been frequently associated with a wide range of biological activities. This is mainly due to their interesting chemical features. For these reasons, for the past decades, researchers have been synthesizing and evaluating guanidine derivatives. In fact, there are currently on the market several guanidine-bearing drugs. Given the broad panoply of pharmacological activities displayed by guanidine compounds, in this review, we chose to focus on antitu...
Source: Bioorganic Chemistry - May 20, 2023 Category: Chemistry Authors: Ana R Gomes Carla L Varela Ana S Pires Elisi ário J Tavares-da-Silva Fernanda M F Roleira Source Type: research
Supportive Care for Patients With Myelodysplastic Syndromes
Cancer J. 2023 May-Jun 01;29(3):168-178. doi: 10.1097/PPO.0000000000000661.ABSTRACTMyelodysplastic syndromes are a heterogeneous group of bone marrow disorders characterized by ineffective hematopoiesis, progressive cytopenias, and an innate capability of progressing to acute myeloid leukemia. The most common causes of morbidity and mortality are complications related to myelodysplastic syndromes rather than progression to acute myeloid leukemia. Although supportive care measures are applicable to all patients with myelodysplastic syndromes, they are especially essential in patients with lower-risk disease who have a bette...
Source: Cancer Journal - May 17, 2023 Category: Cancer & Oncology Authors: Jessica M Stempel Nikolai A Podoltsev Talib Dosani Source Type: research
