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Critical Issues in Communication and Individualizing Treatment for Patients With Colorectal Cancer
Video Module - In this interactive program, John L. Marshall, MD, and Daniel Z. Sands, MD, MPH, FACP, FACMI, provide expert perspective on colorectal cancer treatment, apply the latest clinical data on case studies, and demonstrate and discuss how to apply the principles of participatory medicine to clinical practice.
Source: Clinical Care Options Colorectal Cancer - January 30, 2015 Category: Cancer & Oncology Source Type: research
The cost-effectiveness of training US primary care physicians to conduct colorectal cancer screening in family medicine residency programs
Conclusions A national overhaul of family medicine residency programs offering training for colorectal cancer screening yields satisfactory incremental cost-effectiveness ratios. However, the model places high expectations on primary care physicians to improve current compliance levels in the US.
Source: Preventive Medicine - February 10, 2016 Category: Global & Universal Source Type: research
Does Thrombolysis Have a Place in the Cardiopulmonary Resuscitation of Patients With Acute Pulmonary Embolism? A Case of Successful Thrombolysis During Pulmonary Embolism Induced Cardiopulmonary Arrest
Conclusion: As bedside echocardiographic technology becomes more rapidly and readily available, the rapid diagnosis of pulmonary embolism and use of thrombolytics during cardiopulmonary resuscitation may need to be more routinely considered a potential therapeutic adjunctive measure.
Source: Critical Care Medicine - April 16, 2016 Category: Emergency Medicine Tags: Online Case Report Source Type: research
Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine
ConclusionsUse of a panel of 415 genes can reliably identify all of the critical mutations in CRC patients and this information of CGS can be used to determine the most optimal treatment for patients of all ethnicities.
Source: Genome Medicine - December 21, 2016 Category: Genetics & Stem Cells Source Type: research
Teaching Primary Care Genetics: A Randomized Controlled Trial Comparison.
CONCLUSION: FMRs acquired knowledge and improved skills in genetic medicine with three educational methods. Resources such as faculty expertise in genetic medicine and cost should guide decisions on curricular development for this rapidly expanding field. This may be especially relevant for programs with distributed teaching sites.
PMID: 28633170 [PubMed - in process]
Source: Famly Medicine - June 1, 2017 Category: Primary Care Authors: Telner D, Carroll JC, Regehr G, Tabak D, Semotiuk K, Freeman R Tags: Fam Med Source Type: research
Survival in Older Adults With Metastatic Colorectal Cancer Survival in Older Adults With Metastatic Colorectal Cancer
This paper describes current real-life first-line treatment approaches in older patients with metastatic colorectal cancer. How does survival vary by approach?Journal of the American Geriatrics Society
Source: Medscape Critical Care Headlines - June 13, 2019 Category: Intensive Care Tags: Internal Medicine Journal Article Source Type: news
Genomics And Personalized Medicine: Is It Really Different This Time?
Another year and another annual meeting for the American Society of Clinical Oncology in Chicago. This is a meeting that regularly attracts many thousands of doctors, researchers, pharmaceutical folks and others interested in the science and business of cancer from around the globe to learn, to discuss, to persuade, to educate on the progress being made in clinical cancer research and treatment.
And like every year, there are themes that emerge, that tend to dominate the discussions. And there are other themes that aren't so visible, that don't get as much attention yet in my mind are equally important as they reflect not ...
Source: Dr. Len's Cancer Blog - June 1, 2013 Category: Cancer Authors: Dr. Len Tags: Breast Cancer Cancer Care Colon Cancer Lung Cancer Medications Research Treatment Vaccines Source Type: blogs
Screening and Prevention in Primary Care
Preventive services—both critical and essential to the foundation of primary care—are a unique feature of the primary care specialties. In this issue of Primary Care: Clinics in Office Practice, we selected a wide array of preventive service topics, including the commonly addressed issues of screening for breast cancer, heart disease, colorectal cancer, depression, and substance misuse (alcohol, tobacco, and other substances). Screening for sexually transmitted infections, intimate partner violence, prostate cancer, and lung cancer are also addressed, as well as the topics of preventing unintended pregnancy, genomics i...
Source: Primary Care: Clinics in Office Practice - March 3, 2014 Category: Primary Care Authors: Mack T. Ruffin, Cameron G. Shultz Source Type: research
The impact of companion diagnostic device measurement performance on clinical validation of personalized medicine
A key component of personalized medicine is companion diagnostics that measure biomarkers, for example, protein expression, gene amplification or specific mutations. Most of the recent attention concerning molecular cancer diagnostics has been focused on the biomarkers of response to therapy, such as V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations in metastatic colorectal cancer, epidermal growth factor receptor mutations in metastatic malignant melanoma. The presence or absence of these markers is directly linked to the response rates of particular targeted therapies with small‐molecule kinas...
Source: Statistics in Medicine - March 16, 2015 Category: Statistics Authors: Meijuan Li, Tinghui Yu, Yun‐Fu Hu Tags: Research Article Source Type: research
ReCAP: Association Between the Number of Suppliers for Critical Antineoplastics and Drug Shortages: Implications for Future Drug Shortages and Treatment HEALTH POLICY
QUESTION ASKED:
Cancer drug shortages remain common in the United States and may force oncologists to prioritize patients for treatment, improvise standard treatment regimens, and potentially choose unproven treatment options for patients with curable disease. Because increased competition may reduce drug shortages, the objective of our study was to investigate the association between the number of suppliers for first-line breast, colon, and lung antineoplastics and resulting drug shortages.
SUMMARY ANSWER:
Among 35 antineoplastic drugs approved for first-line treatment of breast, colon, and lung cancer, we saw an overall...
Source: Journal of Oncology Practice - March 9, 2016 Category: Cancer & Oncology Authors: Parsons, H. M., Schmidt, S., Karnad, A. B., Liang, Y., Pugh, M. J., Fox, E. R., Parsons, H. M., Schmidt, S., Karnad, A. B., Liang, Y., Pugh, M. J., Fox, E. R. Tags: Access to care, Legislative issues, Regulatory issues, Population and Observational Studies, Onco-Politics, Outcomes Research HEALTH POLICY Source Type: research
Paid sick leave and preventive health care service use among U.S. working adults
Publication date: Available online 9 February 2017 Source:Preventive Medicine Author(s): LeaAnne DeRigne, Patricia Stoddard-Dare, Cyleste Collins, Linda Quinn Managing work and health care can be a struggle for many American workers. This paper explored the relationship between having paid sick leave and receiving preventive health care services, and hypothesized that those without paid sick leave would be less likely to obtain a range of preventive care services. In 2016, cross-sectional data from a sample of 13,545 adults aged 18–64 with current paid employment from the 2015 National Health Interview Survey (NHIS) wer...
Source: Preventive Medicine - February 8, 2017 Category: Global & Universal Source Type: research
Impact of Practice Facilitation in Primary Care on Chronic Disease Care Processes and Outcomes: a Systematic Review
The objective is to evaluate the impact of practice facilitation on chronic disease outcomes in the primary care setting.MethodsThis systematic review examined North American studies from PubMed, EMBASE, and Web of Science (database inception to August 2017). Investigators independently extracted and assessed the quality of the data on chronic disease process and clinical outcome measures. Studies implemented practice facilitation and reported quantifiable care processes and patient outcomes for chronic disease. Each study and their evidence were assessed for risk of bias and quality according to the Cochrane Collaboration...
Source: Journal of General Internal Medicine - July 31, 2018 Category: Internal Medicine Source Type: research
Disparities in Quality of Primary Care by Resident and Staff Physicians: Is There a Conflict Between Training and Equity?
ConclusionAfter controlling for differences in sociodemographic and clinical factors, resident patients were less likely to achieve chronic disease and preventive cancer screening outcomes compared to staff patients. Further efforts to address ambulatory trainee education and primary care quality along with novel approaches to the management of the disproportionately disadvantaged resident patient panels are needed.
Source: Journal of General Internal Medicine - April 7, 2019 Category: Internal Medicine Source Type: research
Everyone Is Having the Wrong Healthcare Debate
By STEVEN MERAHN, MD
In 1807, in an effort to spite the British and French for shipping interference (and forced recruitment of American citizens into military service), the United States Congress passed an Embargo Act, effectively shutting down trade with these two countries. Britain and France quickly found other trading partners; the US, then limited in our capacity to sell products outside our borders, was left with a devastated economy and a gaping hole in our face. It took only weeks before Congress passed a loophole; they repealed the act within 15 months of its passing. It was a great lesson in unintended co...
Source: The Health Care Blog - August 16, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Politics Uncategorized Health care debate Health Care Reform Steven Merahn universal healthcare Source Type: blogs
The Affordable Care Act and Ethnic Disparities in Colorectal Cancer Screening
ConclusionsThese findings suggest that Affordable Care Act implementation resulted in increased colorectal cancer screening; however, the effect of the law was not significantly different between Hispanics and non-Hispanics. These results provide indications that more needs to be done to reduce racial/ethnic disparities in colorectal cancer screening.
Source: American Journal of Preventive Medicine - January 17, 2020 Category: International Medicine & Public Health Source Type: research
