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Cancer: Colorectal Cancer
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Total 365 results found since Jan 2013.

Geographical Distribution of Colorectal Cancer in Southwestern Iran Between Years 2011 and 2019
CONCLUSION: The cumulative incidence of colorectal cancer is relatively high in Khuzestan province. The cumulative incidence of the disease was higher in the central regions of the province than in other regions. Also, based on geographical areas, the cumulative incidence of the disease was higher in areas with arid climates, the average rainfall was 100-200 mm, and in areas with agricultural land use.PMID:37681264 | DOI:10.5152/tjg.2023.22666
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Changiz Rostami Arghavan Feyzmanesh Arezoo Karimi Salman Daliri Source Type: research

Impacts of some clinicopathodemography and colorectal tissues key cell cycle and mucin stabilizing molecules on the metastasis trend in colorectal cancer patients
CONCLUSION: B3GALNT2, MUC1, and "Ki67" can be used as promising biomarkers for prognosis and early diagnosis of increasingly/predominantly non-genetic/environmental originated metastatic CRCs.PMID:37644368 | DOI:10.1007/s11033-023-08766-x
Source: Mol Biol Cell - August 29, 2023 Category: Molecular Biology Authors: Ali Ghorbani Ranjbary Jalil Mehrzad Nasrollah Rahbar Hesam Dehghani Source Type: research

The Effect of Mediterranean Diet on Body Composition, Inflammatory Factors, and Nutritional Status in Patients with Cachexia Induced by Colorectal Cancer: A Randomized Clinical Trial
CONCLUSION: It appears that the implementation of the Mediterranean diet might be a strategy to improve nutritional status, quality of life, inflammatory markers, and body composition in patients with colorectal cancer cachexia.TRIAL REGISTRATION: Iranian Registry of Clinical Trials (www.irct.ir); ID: IRCT20211027052884N1.PMID:37621140 | DOI:10.1177/15347354231195322
Source: Cancer Control - August 25, 2023 Category: Cancer & Oncology Authors: Amir Bagheri Farzaneh Asoudeh Saied Rezaei Mohammad Babaei Ahmad Esmaillzadeh Source Type: research

Exploring the anticancer properties of the gum of < em > Ferula gummosa < /em > : impact on cytotoxicity, caspase 3/7 activity and apoptosis, and gene expression in SW-480 cells
This study aimed to identify the chemical components of the gum of F. gummosa and investigate its effects on SW-480 cells. The experiments included MTT, clonogenic, micronucleus formation, acridine orange/ethidium bromide stain, DNA degradation, caspase 3/7 activity assay, and in vitro wound-healing experiment and investigating the expression of BAX, BCL2, MTOR, and PTEN genes. Chemical analysis using GC/MS identified 102 compounds. The gum had a significant cytotoxic effect on SW-480 cells, with an IC50 value of 1.8 µg/ml for 48 hours. The gum induced apoptosis. Microscopic observations revealed a decrease in cell prolif...
Source: Cell Research - August 11, 2023 Category: Cytology Authors: Parisa Bahavar Majid Tafrihi Source Type: research