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Cancer: Colorectal Cancer
Nutrition: Zinc
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Total 263 results found since Jan 2013.
Green synthesis of multifunctional zinc oxide nanoparticles from cordia myxa gum; and their catalytic reduction of nitrophenol, anticancer and antimicrobial activity
This study uses CMX gum as a bioreduction to produce multifunctional, environmentally friendly zinc-oxide nanocomposites (ZnO NPs). The process involves a low reaction time and temperature and utilizes CMX as a reducing and stabilizing agent. The structural, morphological, and optical properties of the CMX-ZnO nanocomposite were characterized. The biosynthetic CMX-ZnO NPs exhibited robust catalytic activity and recycling capacity for rapidly oxidizing hazardous p-NPs. The complete reduction of 4-NP to CMX-ZnO NPs in excess NaBH4 was achieved within 15 min, with recyclability and pseudo-first-order kinetics with a rate cons...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Kasula Nagaraja O H Tae Hwan Source Type: research
Zinc intake, SLC30A8 rs3802177 polymorphism, and colorectal cancer risk in a Korean population: a case-control study
CONCLUSIONS: In summary, our findings suggest an inverse association between dietary zinc intake and CRC risk, and this relationship may be modified by SLC30A8 rs3802177 polymorphism.PMID:37707576 | DOI:10.1007/s00432-023-05381-y
Source: Clinical Colorectal Cancer - September 14, 2023 Category: Cancer & Oncology Authors: Linh Thi Dieu Nguyen Madhawa Gunathilake Jeonghee Lee Jae Hwan Oh Hee Jin Chang Dae Kyung Sohn Aesun Shin Jeongseon Kim Source Type: research
LncRNA RPLP0P2 Promotes Colorectal Cancer Proliferation and Invasion via the miR-129-5p/Zinc Finger and BTB Domain-Containing 20 Axis
In this study, we observed that RPLP0P2 was upregulated in CRC tissues and cell lines. Cell viability was measured using the MTT and colony formation assays. Migration and invasion capabilities were monitored by wound healing, transwell, and immunofluorescence assays. The results showed that RPLP0P2 downregulation inhibited cell viability, migration, and invasion capabilities of CRC cells, accompanied by decreased PCNA, N-cadherin, and Vimentin, and increased E-cadherin expression. Using the DIANA online database, miR-129-5p was identified as a downstream target of RPLP0P2. In fact, RPLP0P2 colocalized with miR-129-5p, act...
Source: Biochemical Genetics - August 31, 2023 Category: Genetics & Stem Cells Authors: Hang Yuan Peng Yu Zi-Ang Wan Bing-Chen Chen Shi-Liang Tu Source Type: research
pH-Responsive Zinc Ion Regulating Immunomodulatory Nanoparticles for Effective Cancer Immunotherapy
Biomacromolecules. 2023 Aug 24. doi: 10.1021/acs.biomac.3c00557. Online ahead of print.ABSTRACTHerein, we introduce a novel approach involving the utilization of a human serum albumin-coated zeolite imidazolate framework-8 containing a photosensitizer (HPZ) that exhibits targeted recognition of the tumor microenvironment, enabling the rapid elevation of zinc ion concentrations while facilitating the controlled release of an encapsulated photosensitizer (PS). At a physiological pH of 7.4, HPZ demonstrates a size of approximately 170 nm, significantly decreasing to less than 10 nm under pH 6.5 acidic conditions. Acid-induced...
Source: Biomacromolecules - August 24, 2023 Category: Biochemistry Authors: Byoungjun Lim Kyoung Sub Kim Kun Na Source Type: research
Food Intake and Colorectal Cancer
Nutr Cancer. 2023 Aug 12:1-33. doi: 10.1080/01635581.2023.2242103. Online ahead of print.ABSTRACTColorectal cancer (CRC) accounts for considerable mortalities worldwide. Several modifiable risk factors, including a high intake of certain foods and beverages can cause CRC. This review summarized the latest findings on the intake of various foods, nutrients, ingredients, and beverages on CRC development, with the objective of classifying them as a risk or protective factor. High-risk food items include red meat, processed meat, eggs, high alcohol consumption, sugar-sweetened beverages, and chocolate candy. Food items that ar...
Source: Nutrition and Cancer - August 12, 2023 Category: Cancer & Oncology Authors: Akshaya Kumar Shanmugavel Chinnathambi Magi Kumar Ganesh N Pandian Source Type: research
