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Condition: Alcoholism
Cancer: Colorectal Cancer

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Total 839 results found since Jan 2013.

Correlation between High Incidence of Colorectal Neoplastic Polyps and High-risk Adenomas in Patients with Diabetes Mellitus: A Retrospective Study
CONCLUSION: This study demonstrated that patients with DM, age ≥ 50 years, male gender, alcohol consumption, and a first-degree relative with a history of CRC should undergo regular endoscopic screening and colonic polypectomy.PMID:37711116 | DOI:10.2174/1871530323666230913105743
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Chuan-Yu Zheng Wa Zhong Ji-Hao Xu Yu-Hong Yuan Nai-Zhao Chen Wei-Ling Liang Qi-Kui Chen Yu Lai Source Type: research

Collection of cancer-specific data in population-based surveys in low- and middle-income countries: A review of the demographic and health surveys
PLOS Glob Public Health. 2023 Sep 8;3(9):e0002332. doi: 10.1371/journal.pgph.0002332. eCollection 2023.ABSTRACTPopulation-based surveys, such as those conducted by the Demographic and Health Surveys (DHS) Programme, can collect and disseminate the data needed to inform cancer control efforts in a standardised and comparable manner. This review examines the DHS questionnaires, with the aim of describing and analysing how cancer-specific questions have been asked from the inception of the surveys to date. A systematic search of the DHS database was conducted to identify cancer-specific questions asked in surveys. Descriptive...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Chukwudi A Nnaji Jennifer Moodley Source Type: research

The role of aldose reductase in polyol pathway: An emerging pharmacological target in diabetic complications and associated morbidities
Curr Pharm Biotechnol. 2023 Aug 30. doi: 10.2174/1389201025666230830125147. Online ahead of print.ABSTRACTThe expression of aldose reductase leads to a variety of biological and pathological effects. It is a multifunctional enzyme which has a tendency to reduce aldehydes to the corresponding sugar alcohol. In diabetic conditions, the aldose reductase enzyme converts glucose into sorbitol using nicotinamide adenine dinucleotide phosphate as a cofactor. It is a key enzyme in polyol pathway which is a surrogate course of glucose metabolism. The polyol pathway has a significant impact on the aetiology of complications in indiv...
Source: Current Pharmaceutical Biotechnology - August 31, 2023 Category: Biotechnology Authors: Jeetendra Kumar Gupta Source Type: research

Impact of Matrix Metalloproteinase-8 Genotypes on Colorectal Cancer Risk in Taiwan
CONCLUSION: The analyzed genotypes of MMP-8 play a minor role in determining individual susceptibility to CRC risk.PMID:37648297 | DOI:10.21873/anticanres.16585
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Yang Deng Tao-Wei Ke Yun-Chi Wang Yu-Ting Chin Te-Cheng Yueh Yi-Chih Hung Mei-Chin Mong Ya-Chen Yang Wen-Shin Chang Te-Chun Shen DA-Tian Bau Chia-Wen Tsai Source Type: research

MLH1 rs1800734 Pathogenic Variant among Patients with Colorectal Cancer in the Lower Northeastern Region of Thailand
CONCLUSION: This study showed that MLH1 rs1800734 genotype AA was associated with colorectal cancer risk in the lower northeastern region of Thailand.PMID:37642081 | DOI:10.31557/APJCP.2023.24.8.2911
Source: Cancer Control - August 29, 2023 Category: Cancer & Oncology Authors: Malinee Pongsavee Kamol Wisuwan Kritpipat Pongsavee Source Type: research

Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research