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Editorial: Shaping of Human Immune System and Metabolic Processes by Viruses and Microorganisms
Conclusions In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases. Author Contributions All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - April 16, 2019 Category: Microbiology Source Type: research

Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Association of atopy and tentative diagnosis of skin cancer – results from occupational skin cancer screenings
ConclusionDesign limitations of the study include that all findings of skin cancer were based on clinical examination only and must therefore be considered tentative diagnoses. Furthermore, owing to the cross‐sectional study design, causal pathways cannot be proven. However, analyses of data from such a large and general population‐based cohort afford valuable insights into the relationship between atopic diseases and skin cancer. They provide the grounds for prospective cohort studies to evaluate and dissect the underlying mechanism.
Source: Journal of the European Academy of Dermatology and Venereology - August 3, 2017 Category: Dermatology Authors: I. Sch äfer, P. Mohr, N. Zander, R. Fölster‐Holst, M. Augustin Tags: Original Article Source Type: research

Nature Contact and Human Health: A Research Agenda
Conclusions: Nature contact may offer a range of human health benefits. Although much evidence is already available, much remains unknown. A robust research effort, guided by a focus on key unanswered questions, has the potential to yield high-impact, consequential public health insights. https://doi.org/10.1289/EHP1663 Received: 26 January 2017 Revised: 12 May 2017 Accepted: 25 May 2017 Published: 31 July 2017 Address correspondence to H. Frumkin, Dept. of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Box 354695, Seattle, WA 98195-4695 USA; Telephone: 206-897-1723;...
Source: EHP Research - July 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research

Association of atopy and tentative diagnosis of skin cancer ‐ results from occupational skin cancer screenings
ConclusionDesign limitations of the study include that all findings of skin cancer were based on clinical examination only and must therefore be considered tentative diagnoses. Furthermore, owing to the cross‐sectional study design, causal pathways cannot be proven. However, analyses of data from such a large and general population‐based cohort afford valuable insights into the relationship of atopic diseases and skin cancer. They provide the grounds for prospective cohort studies to evaluate and dissect the underlying mechanism.This article is protected by copyright. All rights reserved.
Source: Journal of the European Academy of Dermatology and Venereology - July 6, 2017 Category: Dermatology Authors: I. Sch äfer, P. Mohr, N. Zander, R. Fölster‐Holst, M. Augustin Tags: Original Article Source Type: research

Why Would I Be Low in Vitamin D?
My doctors and I test blood levels of vitamin D on everyone we see in our clinic. When the results come in, two things happen: 1. Pretty much everyone is low in vitamin D. 2. Pretty much everyone is shocked that they are low in vitamin D. Why worry about vitamin D? It's important. Multiple studies have shown that people with low levels of Vitamin D have the following: • Weaker bones [1] • Higher mortality rate [2] • More allergies and asthma [3] • Greater risk of cancer [4] • Higher risk of diabetes [5] • Greater risk of heart attacks [6] • Higher rates of MS [7] • Higher risk of infections [8] • More me...
Source: Healthy Living - The Huffington Post - November 20, 2015 Category: Consumer Health News Source Type: news