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Total 29465 results found since Jan 2013.

A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial
ConclusionsThis study did not detect an overall significant difference between SO and NS. Both mouth rinses improved oral health parameters, indicating that systematic assessment and oral care may reduce oral discomfort.Trial registrationNCT02067572
Source: Supportive Care in Cancer - July 22, 2021 Category: Cancer & Oncology Source Type: research

In Limbo: Seven Families ’ Experiences of Encounter with Cancer Care in Norway
Conclusion:This study provides insight into families ’ experiences with cancer care from referral until the start of treatment. Our findings indicate that families often experience cancer care as fragmented and confusing. Although evaluations have shown that the introduction of cancer pathways seems to have a positive effect on waiting times and sta ndardization of examinations across hospitals and regions, there is still potential for improvement in coordination between services, family involvement, and emotional and practical support. We argue that our findings highlight the tension between two ideals of professional c...
Source: International Journal of Integrated Care - November 26, 2021 Category: Nursing Source Type: research

Treatment of Lung Cancer with Orally Administered Chinese Herbal Medicine: An Evidence Map between 1970 –2020
ConclusionsCHM has staged and therapeutic advantages in treating lung cancer. The overall methodological quality is poor, and the level of evidence requires improvement. It is necessary to carry out large-scale, standardized, and higher-quality research in the superior and weak areas of CHM treatment of lung cancer.
Source: Chinese Journal of Integrative Medicine - March 3, 2022 Category: Internal Medicine Source Type: research

Efficacy of the Nourishing Yin and Clearing Heat Therapy Based on Traditional Chinese Medicine in the Prevention and Treatment of Radiotherapy-Induced Oral Mucositis in Nasopharyngeal Carcinomas: A Systematic Review and Meta-Analysis of Thirty Randomized Controlled Trials
This study aimed to evaluate the efficacy of nourishing Yin and clearing heat therapy (NYCH therapy) based on traditional Chinese medicine (TCM) in the treatment of radiotherapy-induced oral mucositis (RTOM) in nasopharyngeal carcinomas (NPCs). A total of eight online databases were searched from inception to September 2021 for randomized controlled trials (RCTs). The control group was treated with Western medicine (WM) alone, whereas the experimental group was treated with a combined NYCH and WM therapy. A total of 30 RCTs involving 2562 participants were ultimately included. NYCH therapy combined with conventional WM del...
Source: Evidence-based Complementary and Alternative Medicine - May 9, 2022 Category: Complementary Medicine Authors: Jinsheng Huang Jun Kan Teng Fan Qi Quan Xujia Li Qi Jiang Bei Zhang Guifang Guo Source Type: research

Japanese Kampo Medicine Juzentaihoto Improves Antiviral Cellular Immunity in Tumour-Bearing Hosts
Evid Based Complement Alternat Med. 2022 Aug 13;2022:6122955. doi: 10.1155/2022/6122955. eCollection 2022.ABSTRACTGlobal and antigen-independent immunosuppression by growing tumours can cause life-threating damage when concurrent with an infection in tumour-bearing hosts. In the present study, we investigated whether the oral administration of the Japanese traditional herbal (Kampo) medicine, juzentaihoto (JTT), plays a role in the improvement of antiviral cellular immunity in tumour-bearing hosts. Female BALB/c mice subcutaneously injected with murine colorectal cancer CT26 cells fed a control or JTT diet were inoculated ...
Source: Evidence-based Complementary and Alternative Medicine - August 23, 2022 Category: Complementary Medicine Authors: Shun Takaku Masumi Shimizu Rimpei Morita Source Type: research

Retrospective Clinical Study on Integrated Chinese and Western Medicine in Treatment of Limited-Stage Small Cell Lung Cancer
ConclusionThe combination treatment of CM and WM with continuing oral administration of CM treatment after the first-line chemoradiotherapy for LS-SCLC patients produced better prognosis, lower risks of progression, and longer survival than the WM treatment alone. (Registration No. ChiCTR2200056616)
Source: Chinese Journal of Integrative Medicine - January 6, 2023 Category: Internal Medicine Source Type: research

Application and Effectiveness of Chinese Medicine in Regulating Immune Checkpoint Pathways
In this study, we analyzed the modulation and mechanisms of immune checkpoint molecules associated with different coinhibitory and costimulatory molecules, and reviewed the immune functions of related molecules and CM studies in treating autoimmune diseases and tumors. By summarizing the characteristics and research value of CM in regulating immune checkpoint molecules, this review aims to provide a useful reference for future studies in this field.
Source: Chinese Journal of Integrative Medicine - August 15, 2023 Category: Internal Medicine Source Type: research

Analgesic Effect of Switching From Oral Opioids to a Once-a-Day Fentanyl Citrate Transdermal Patch in Patients With Lung Cancer.
Abstract A new once-a-day fentanyl citrate transdermal patch was developed in Japan. We retrospectively investigated analgesic and adverse effects of this drug in 24 patients with lung cancer. All patients were started on this patch by switching from an oral opioid. The mean pain score before switching was 2.45 (0-5); 48 hours after switching, 15 of the 24 patients showed a decreased pain score and the mean score (2.00) was significantly lower than that before switching. Of the 16 patients who had adverse effects of oral opioids, 7 patients showed improvement in their symptoms after switching. Two patients showed ...
Source: The American Journal of Hospice and Palliative Care - December 21, 2012 Category: Palliative Care Authors: Takakuwa O, Oguri T, Maeno K, Yokoyama M, Hijikata H, Uemura T, Ozasa H, Ohkubo H, Miyazaki M, Niimi A Tags: Am J Hosp Palliat Care Source Type: research

Patient-Oncologist Alliance, Psychosocial Well-Being, and Treatment Adherence Among Young Adults With Advanced Cancer Palliative and Supportive Care
Conclusion By developing a strong alliance, oncologists may enhance psychosocial well-being and increase treatment adherence in young adult patients with advanced cancer.
Source: Journal of Clinical Oncology - April 26, 2013 Category: Cancer & Oncology Authors: Trevino, Fasciano, Prigerson Tags: Outcomes Research, Quality of Life Palliative and Supportive Care Source Type: research

Aggravation of Fatigue by Steroid Therapy in Terminally Ill Patients With Cancer.
In conclusion, the possibility of steroid-induced secondary fatigue in terminally ill cancer patients should be taken into consideration. PMID: 23588576 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - April 15, 2013 Category: Palliative Care Authors: Matsuo N, Yomiya K Tags: Am J Hosp Palliat Care Source Type: research

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials
DiscussionManaging dry mouth with treatment supported by the best possible evidence will improve functional status of patients, and improve quality of life for patients and carers. Using n-of-1 trials will accelerate the rate of accumulation of high-grade evidence to support clinical therapies used in PC.Trial registration: Australia and New Zealand Clinical Trial Registry Number: 12610000840088.
Source: BMC Palliative Care - Latest articles - October 31, 2013 Category: Palliative Care Authors: Jane NiklesGeoffrey MitchellJanet HardyMeera AgarHugh SeniorSue-Ann CarmontPhilip SchluterPhillip GoodRohan VoraDavid Currow Source Type: research

Efficacy and Gastrointestinal Tolerability of Oral Oxycodone/Naloxone Combination for Chronic Pain in Outpatients With Cancer: An Observational Study.
Abstract Combination opioid agonist/antagonist therapy has been shown to preserve bowel function in patients with chronic cancer pain. This retrospective study evaluated the efficacy and tolerability of prolonged-released fixed-dose oxycodone-naloxone (PR OXN) in consecutive outpatients with chronic cancer pain. Of 206 patients prescribed PR OXN (mean age 61.3 ± 12.9 years; 52.9% female), 31.5% were opioid naïve. PR OXN was associated with a significant decrease in pain score measured on a visual analogue scale over 28 days (P < .0001), without adverse effects on bowel function, nor change in laxative use. PR...
Source: The American Journal of Hospice and Palliative Care - November 17, 2013 Category: Palliative Care Authors: Cuomo A, Russo G, Esposito G, Forte CA, Connola M, Marcassa C Tags: Am J Hosp Palliat Care Source Type: research

Diseases of the mouth.
This article discusses prevalence, cause, diagnosis, and management of lesions such as stomatitis, candidiasis, caries, oral cancers, and bony tori. PMID: 24439882 [PubMed - in process]
Source: Primary Care - January 21, 2014 Category: Primary Care Authors: Silk H Tags: Prim Care Source Type: research