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Cancer: Bile Duct Cancer

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Total 737 results found since Jan 2013.

Significant CA 19-9 Elevation in IgG4-Related Autoimmune Pancreatitis - A Diagnostic Dilemma
We describe the case of a 65-year-old male with history of IgG4-RD, presenting with jaundice and abdominal pain. He was found to have a pancreatic mass with significantly elevated IgG4 162 (2-96 mg/dL and CA19-9 levels 2830 (0-35 U/ml). Patient underwent ERCP and biopsy, which ruled out pancreatic cancer and cholangiocarcinoma. He was diagnosed with IgG4-RD autoimmune pancreatitis (AIP) and sclerosing cholangitis. Treatment with steroids and rituximab resulted in significant improvement in the bilirubin and a dramatic decrease in CA19-9 levels.PMID:37714269 | DOI:10.1016/j.amjms.2023.09.016
Source: The American Journal of the Medical Sciences - September 15, 2023 Category: General Medicine Authors: Larabe Farrukh Muhammad Farhan Akhtar Hafiza Hareem Waqar Ruben Peredo-Wende Source Type: research

Simultaneously metastatic cholangiocarcinoma and small intestine cancer from breast cancer misdiagnosed as primary cholangiocarcinoma: A case report
CONCLUSION: Simultaneous metastatic cholangiocarcinoma and small intestine cancer from breast cancer are rare and the prognosis is extremely poor. Improving preoperative diagnostic accuracy is beneficial to avoid excessive surgical treatment. Treatment should be aimed at relieving biliary obstruction and abdominal pain, and then supplemented with chemotherapy and targeted therapy to control tumor progression and prolong the patient's life.PMID:37449239 | PMC:PMC10336993 | DOI:10.12998/wjcc.v11.i18.4446
Source: Clinical Genitourinary Cancer - July 14, 2023 Category: Cancer & Oncology Authors: Xin Jiao Mi-Mi Zhai Fang-Zhou Xing Xiao-Ling Wang Source Type: research

Exploring the molecular pathogenesis, diagnosis and treatment of fibrolamellar hepatocellular carcinoma: A state of art review of the current literature
This study aims to present a comprehensive overview of fibrolamellar carcinoma (FLC), with a focus on its epidemiology, pathogenesis, diagnosis, treatment, and prognosis. FLC frequently incorporate features of stomach pain, weight loss, and malaise in their clinical signs and symptoms, which are generally nonspecific Ultimately, the most common physical finding is an abdominal mass or hepatomegaly. With this said, several unusual presentations have been documented such as Budd Chiari syndrome, severe anaemia, non-bacterial thrombotic endocarditis and many more. In regards to this tumour's genetic analysis, it is characteri...
Source: Pathology, Research and Practice - July 10, 2023 Category: Pathology Authors: Yasir Alshareefy Chai Yu Shen Rosheene Jeya Prekash Source Type: research

FDA Approval Summary: Futibatinib for Unresectable Advanced or Metastatic, Chemotherapy Refractory Intrahepatic Cholangiocarcinoma with FGFR2 Fusions or Other Rearrangements
This article summarizes the FDA's thought process and data supporting the approval of futibatinib.PMID:37289037 | DOI:10.1158/1078-0432.CCR-23-1042
Source: Clinical Cancer Research - June 8, 2023 Category: Cancer & Oncology Authors: Shruti U Gandhy Sandra J Casak Sirisha L Mushti Joyce Cheng Sriram Subramaniam Hong Zhao Miao Zhao Youwei Bi Guansheng Liu Jianghong Fan Oluseyi Adeniyi Rosane Charlab Dubravka Kufrin Matthew D Thompson Kristin Jarrell Doris Auth Steven J Lemery Richard P Source Type: research

Causes and management of endoscopic retrograde cholangiopancreatography-related perforation: A retrospective study
CONCLUSIONS: Early diagnosis and appropriate treatment are important in managing ERCP-related perforation.PMID:37271549 | DOI:10.1272/jnms.JNMS.2023_90-305
Source: Journal of Nippon Medical School - June 4, 2023 Category: Universities & Medical Training Authors: Tetsuya Shimizu Masato Yoshioka Akira Matsushita Keiko Kaneko Junji Ueda Mampei Kawashima Toshiyuki Irie Takashi Ono Hiroyasu Furuki Tomohiro Kanda Yoshiaki Mizuguchi Yoichi Kawano Yoshiharu Nakamura Hiroshi Yoshida Source Type: research