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Total 121623 results found since Jan 2013.
Cutaneous manifestations of gastrointestinal disease: Part I
Cutaneous findings are not uncommonly a concomitant finding in patients afflicted with gastrointestinal (GI) diseases. The dermatologic manifestations may precede clinically evident GI disease. Part I of this 2-part CME review focuses on dermatologic findings as they relate to hereditary and nonhereditary polyposis disorders and paraneoplastic disorders. A number of hereditary GI disorders have an increased risk of colorectal carcinomas. These disorders include familial adenomatous polyposis, Peutz–Jeghers syndrome, and juvenile polyposis syndrome. Each disease has its own cutaneous signature that aids dermatologists in ...
Source: Journal of the American Academy of Dermatology - January 14, 2013 Category: Dermatology Authors: Kejal R. Shah, C. Richard Boland, Mahir Patel, Breck Thrash, Alan Menter Tags: Continuing Medical Education Source Type: research
The spectrum of oculocutaneous disease: Part II. Neoplastic and drug-related causes of oculocutaneous disease
There are a multitude of diseases that commonly affect both the skin and the eye. Part II of this 2-part series reviews the oculocutaneous manifestations of neoplasms, both benign and malignant, and adverse drug reactions affecting the skin and the eye. Though rare, a number of neoplasms that primarily involve the skin, such as melanoma and basal cell carcinoma, can metastasize to the eye, leading to permanent damage if not properly treated. In addition, periocular neoplasms can irritate the conjunctiva and lid, reducing a patient's ability to see clearly. Neoplastic diseases, such as xeroderma pigmentosum, Sturge–Weber ...
Source: Journal of the American Academy of Dermatology - April 17, 2014 Category: Dermatology Authors: Antoinette Day, Amanda K. Abramson, Mahir Patel, Richard B. Warren, M. Alan Menter Tags: Continuing Medical Education Source Type: research
Advanced liver disease: what every hepatitis C virus treater should know.
This article summarizes a presentation by Kenneth E. Sherman, MD, at the IAS-USA live continuing medical education course, Management of Hepatitis C Virus in the New Era, held in New York City in April 2011.
PMID: 21946390 [PubMed - indexed for MEDLINE]
Source: Topics in antiviral medicine - November 12, 2014 Category: Infectious Diseases Tags: Top Antivir Med Source Type: research
Cutaneous adverse effects of targeted therapies
The last decade has spawned an exciting new era of oncotherapy in dermatology, including the development of targeted therapies for metastatic melanoma and basal cell carcinoma. Along with skin cancer, deregulation of the PI3K-AKT-mTOR and RAS-RAF-MEK-ERK intracellular signaling pathways contributes to tumorigenesis of a multitude of other cancers, and inhibitors of these pathways are being actively studied. Similar to other classes of targeted therapies, cutaneous adverse effects are among the most frequent toxicities observed with mitogen-activated protein kinase pathway inhibitors, PI3K-AKT-mTOR inhibitors, hedgehog sig...
Source: Journal of the American Academy of Dermatology - January 15, 2015 Category: Dermatology Authors: James B. Macdonald, Brooke Macdonald, Loren E. Golitz, Patricia LoRusso, Aleksandar Sekulic Tags: Continuing medical education Source Type: research
Exam 3: Comparison of Liver Transplant-related Survival Benefit in Patients With Versus Without Hepatocellular Carcinoma in the United States
Source: Gastroenterology - July 28, 2015 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Exam 3: Comparison of Liver Transplant–Related Survival Benefit in Patients With vs Without Hepatocellular Carcinoma in the United States
Source: Gastroenterology - July 28, 2015 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activity Source Type: research
Exam 1: Trends in the Burden of Cirrhosis and Hepatocellular Carcinoma by Underlying Liver Disease in US Veterans From 2001 to 2013
Source: Gastroenterology - September 23, 2015 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Exam 1: Trends in Burden of Cirrhosis and Hepatocellular Carcinoma by Underlying Liver Disease in US Veterans, 2001–2013
Source: Gastroenterology - September 23, 2015 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Familial skin cancer syndromes
Nonmelanoma skin cancers (NMSCs) represent the most common malignancies worldwide, with reported incidence rising each year. Both cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), as well as other NMSCs, represent complex diseases with a combination of environmental and genetic risk factors. In general, hereditary cancer syndromes that increase the risk of NMSC fall under several broad categories: those associated with immunodeficiencies, those that affect skin pigmentation, and those that perturb key molecular pathways involved in the pathogenesis of NMSCs.
Source: Journal of the American Academy of Dermatology - February 17, 2016 Category: Dermatology Authors: Prajakta D. Jaju, Katherine J. Ransohoff, Jean Y. Tang, Kavita Y. Sarin Tags: Continuing medical education Source Type: research
Exam 1: Regulation of Transdifferentiation and Retrodifferentiation by Inflammatory Cytokines in Hepatocellular Carcinoma
Source: Gastroenterology - August 29, 2016 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Exam 2: Patients With Hepatocellular Carcinoma Have Highest Rates of Wait-listing for Liver Transplantation Among Patients With End-Stage Liver Disease
Source: Clinical Gastroenterology and Hepatology - September 15, 2016 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Exam 3: Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck
Source: Gastroenterology - September 28, 2016 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research
Evidence-Based Medicine: Cutaneous Facial Malignancies: Nonmelanoma Skin Cancer
Learning Objectives: After studying this article, the participant should be able to: 1. Identify clinical features of nonmelanoma skin cancer; 2. Distinguish low-risk versus high-risk basal cell carcinoma and squamous cell carcinoma; 3. Define appropriate management based on current guidelines for various types of basal cell and squamous cell carcinoma.
Summary: Skin malignancies are the most prevalent cancers, and plastic surgeons are often the primary physicians engaged in diagnosis and management of these lesions. Proper management includes distinguishing between high-risk and low-risk lesions and determining treatment...
Source: Plastic and Reconstructive Surgery - December 29, 2016 Category: Cosmetic Surgery Tags: MOC-CME Source Type: research
Exam 3: BRCA1-Associated Protein Increases Invasiveness of Esophageal Squamous Cell Carcinoma
Source: Gastroenterology - October 5, 2017 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activities Source Type: research
Merkel cell carcinoma: An update and review
Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor of the skin associated with a high risk of local recurrence and distant metastases. It most commonly occurs on sun-exposed areas of white patients>65 years of age. The Merkel cell polyomavirus (MCV) is thought to be responsible for malignant transformation in approximately 80% of cases in the northern hemisphere, while ultraviolet radiation–induced DNA damage is implicated in MCV-negative tumors. The overall incidence of MCC is low, with appr oximately 1600 cases diagnosed annually in the United States.
Source: Journal of the American Academy of Dermatology - December 8, 2017 Category: Dermatology Authors: Tiffany L. Tello, Kathleen Coggshall, Sue S. Yom, Siegrid S. Yu Tags: Continuing medical education Source Type: research
