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Specialty: Cancer & Oncology
Cancer: Cancer
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Total 908 results found since Jan 2013.
Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
Front Nutr. 2022 Nov 1;9:1007816. doi: 10.3389/fnut.2022.1007816. eCollection 2022.ABSTRACTMany local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation. The GSH tripeptide (γ- L-glutamyl-L-cysteinyl-glycine), the most abundant w...
Source: Cancer Control - November 17, 2022 Category: Cancer & Oncology Authors: Carlos A Labarrere Ghassan S Kassab Source Type: research
Study Protocol and Baseline Characteristics of Randomized Trial for Evaluating Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, The Combination of a Randomized Control Trial and an Observational Biomarker Study
CONCLUSIONS: After this study is completed, we will have further evidence on whether a highly purified EPA is effective in reducing cardiovascular events for secondary prevention or not, as well as whether if EPA/AA ratio is a predictor for future cardiovascular events.PMID:36372250 | DOI:10.1016/j.ahj.2022.11.008
Source: Cancer Control - November 13, 2022 Category: Cancer & Oncology Authors: Yuji Nishizaki Katsumi Miyauchi Hiroshi Iwata Teruo Inoue Atsushi Hirayama Kazuo Kimura Yukio Ozaki Toyoaki Murohara Kenji Ueshima Yoshihiro Kuwabara Sachiko Tanaka-Mizuno Naotake Yanagisawa Tosiya Sato Hiroyuki Daida Source Type: research
Resiliency intervention for patient-caregiver dyads in the Neuro-ICU: Study protocol for a single-blind randomized clinical trial
DISCUSSION: If successful, we plan to test RT in a large-scale, multisite hybrid effectiveness-implementation study in Neuro-ICUs across the country. Enhancing psychosocial supports for patients and families could improve health outcomes, healthcare efficiency, and the culture of these units.PMID:36368480 | DOI:10.1016/j.cct.2022.106998
Source: Cancer Control - November 11, 2022 Category: Cancer & Oncology Authors: Ana-Maria Vranceanu Emily C Woodworth Millan R Kanaya Sarah Bannon Ryan A Mace Heena Manglani Brooke A Duarte Christina L Rush Nathaniel R Choukas Ellie A Briskin Joshua Cohen Robert Parker Eric Macklin Ethan Lester Lara Traeger Jonathan Rosand Karon M Ko Source Type: research
Association Between Aromatase Inhibitors and Myocardial Infarction Morbidity in Women With Breast Cancer: A Meta-Analysis of Observational Studies
CONCLUSION: Based on real-world data, AIs may be a safe treatment route for patients with estrogen receptor-positive breast cancer and those with a history of CVD. AIs caused a major decrease in MI in patients without CVD history. However, more in-depth investigations are needed to explore the association between AI use and the incidence of MI in the treatment of estrogen receptor-positive breast cancer.PMID:36346929 | DOI:10.1177/10732748221132512
Source: Cancer Control - November 8, 2022 Category: Cancer & Oncology Authors: Jing-Chao Sun Ze-Fan Sun Chao-Jie He Chang-Lin Zhai Gang Qian Source Type: research
The effect of voice training interventions on patients with oropharyngeal dysphagia: a systematic review
CONCLUSIONS: In general, statistically significant positive therapy effects were found. Voice training improves the oral and pharyngeal stages of swallowing in patients with neurological causes of dysphagia, such as stroke, and in patients with non-neurological causes of dysphagia, such as head and neck cancer. However, the current literature is limited and further primary research is required to provide more evidence to support voice training intervention in dysphagia. Future studies could further refine the content of voice training interventions, increase the number of patients enrolled, assess the long-term effects of ...
Source: Cancer Control - November 7, 2022 Category: Cancer & Oncology Authors: Chunyan Niu Wenyan Zhou Haifang Wang Yingying Zhang Jianzheng Cai Nini Lu Yalan Wang Source Type: research
Admission Rates, Time Trends, Risk Factors, and Outcomes of Ischemic and Hemorrhagic Stroke From German Nationwide Data
DISCUSSION: Despite recent advances in acute stroke care over the last decade, the percentage of stroke hospitalizations resulting in death remained unchanged. Further research is needed to determine how best to optimize stroke care pathways for multimorbid patients.PMID:36332988 | DOI:10.1212/WNL.0000000000201259
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Dearbhla M Kelly Jannik Feld Peter M Rothwell Holger Reinecke Jeanette Koeppe Source Type: research
Trimethylamine N-Oxide as a potential risk factor for non-communicable diseases: A systematic review
CONCLUSION: There is a dose-response relationship between TMAO levels and NCDs progression. Therefore, it can be studied as a therapeutic target or prognostic biomarker for dealing with NCDs.PMID:36330632 | DOI:10.2174/1871530323666221103120410
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Zahra Hoseini Tavassol Hanieh-Sadat Ejtahed Bagher Larijani Shirin Hasani-Ranjbar Source Type: research
Ischemic stroke in a patient with EGFR ‐mutated non–small‐cell lung cancer after treatment with ramucirumab
This article presents the case of a non–small-cell lun g cancer patient who experienced a new ischemic stroke after treatment with ramucirumab. The findings suggest that further studies may be necessary to investigate the relationship between ramucirumab and the risk of ischemic stroke.
Source: Thoracic Cancer - October 29, 2022 Category: Cancer & Oncology Authors: Guo ‐Yu Chen,
Wen‐Chien Cheng,
Chih‐Yen Tu Tags: CASE REPORT Source Type: research
Neurovascular Manifestations of Iron-Deficient Anemia: Narrative Review and Practical Reflections through a Teaching Case
Conclusions: IDA is a common but treatable condition that, independently or synergically, may increase the risk of thrombotic events. The diagnostic and therapeutic approach has not yet been defined, and each case should be individually addressed in a pragmatic clinical road map.PMID:36294407 | DOI:10.3390/jcm11206088
Source: Clinical Lung Cancer - October 27, 2022 Category: Cancer & Oncology Authors: Marialuisa Zedde Giacomo Portaro Laura Ferri Francesco Cavallieri Manuela Napoli Claudio Moratti Fabrizio Piazza Franco Valzania Rosario Pascarella Source Type: research
Evaluation of a Novel Synthetic Peptide Derived from Cytolytic Mycotoxin Candidalysin
Toxins (Basel). 2022 Oct 11;14(10):696. doi: 10.3390/toxins14100696.ABSTRACTThe importance of neuroinflammation in neurology is becoming increasingly apparent. In addition to neuroinflammatory diseases such as multiple sclerosis, the role of neuroinflammation has been identified in many non-inflammatory neurological disorders such as stroke, epilepsy, and cancer. The immune response within the brain involves the presence of CNS resident cells; mainly glial cells, such as microglia, the CNS resident macrophages. We evaluated the peptide Ca-MAP1 bioinspired on the C. albicans immature cytolytic toxin candidalysin to develop ...
Source: Cancer Control - October 26, 2022 Category: Cancer & Oncology Authors: Pedro Henrique de Oliveira Cardoso Ana Paula de Ara újo Boleti Patr ícia Souza E Silva Lincoln Takashi Hota Mukoyama Alexya Sandim Guindo Luiz Filipe Ramalho Nunes de Moraes Caio Fernando Ramalho de Oliveira Maria Ligia Rodrigues Macedo Cristiano Marcel Source Type: research
Risk Factors and In-Hospital Outcomes of Perioperative Atrial Fibrillation for Patients with Cancer: A Meta-Analysis
CONCLUSIONS: For patients with cancer, POAF is associated with an increased burden of comorbidities and worse outcomes.PMID:36273057 | DOI:10.1245/s10434-022-12690-y
Source: Ann Oncol - October 22, 2022 Category: Cancer & Oncology Authors: Keiko Inoue Kazuko Tajiri DongZhu Xu Nobuyuki Murakoshi Masaki Ieda Source Type: research
Can mental practice adjunct in the recovery of motor function in the upper limbs after stroke? A systematic review and meta-analysis
CONCLUSION: Current evidence does not support the use of the mental practice to increase the recovery of the upper limb after stroke, although the evidence is conflicting for some aspects of the technique.PMID:36267434 | PMC:PMC9578308 | DOI:10.4103/bc.bc_28_22
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Danielle Aprigio Juliana Bittencourt Maria Ramim Victor Marinho Igor Brauns Isabelle Fernandes Pedro Ribeiro Bruna Velasques Ana Catarina Alves E Silva Source Type: research
Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration
The objectives of this study were to (1) determine the effect of MMP-12 suppression by shRNA-mediated gene silencing on neurological/functional recovery, (2) establish the optimal timing of MMP-12shRNA treatment that provides maximum therapeutic benefit, (3) compare the effectiveness of acute versus chronic MMP-12 suppression, and (4) evaluate potential sex-related differences in treatment outcomes. Young male and female Sprague-Dawley rats were subjected to transient middle cerebral artery occlusion and reperfusion. Cohorts of rats were administered either MMP-12shRNA or scrambled shRNA sequence (control) expressing plasm...
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Siva Reddy Challa Koteswara Rao Nalamolu Casimir A Fornal Billy C Wang Ryan C Martin Elsa A Olson Ammar L Ujjainwala David M Pinson Jeffrey D Klopfenstein Krishna Kumar Veeravalli Source Type: research
Role of Serum Homocysteine and Outcome in Patients With Traumatic Brain Injury
Conclusion The study concluded that patients who had suffered from a TBI had significantly higher serum Hcy levels. Furthermore, the study highlighted that the patients with the worst outcomes had more severe hyperhomocysteinemia (HHcy) than those with better outcomes. Moreover, patients with low GOS scores were more likely to have HHcy.PMID:36237797 | PMC:PMC9548089 | DOI:10.7759/cureus.28968
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Humayoun Amini Hewad Hewadmal Sayed Farhad Rasuli Chowdhury S Shahriar Abdul Fattah Hariharan Kavanoor Sridhar Marjan Khan Sadaf Bhat Abdul Subhan Talpur Laila Tul Qadar Source Type: research
