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HMG CoA reductase inhibitors (statins) for kidney transplant recipients.
CONCLUSIONS: Statins may reduce cardiovascular events in kidney transplant recipients, although treatment effects are imprecise. Statin treatment has uncertain effects on overall mortality, stroke, kidney function, and toxicity outcomes in kidney transplant recipients. Additional studies would improve our confidence in the treatment benefits and harms of statins on cardiovascular events in this clinical setting. PMID: 24470059 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - February 3, 2014 Category: Journals (General) Authors: Palmer SC, Navaneethan SD, Craig JC, Perkovic V, Johnson DW, Nigwekar SU, Hegbrant J, Strippoli GF Tags: Cochrane Database Syst Rev Source Type: research

Hormone Therapy in Women After Heart Transplantation
Conclusions: HT is not associated with poor outcome or adverse effects in female heart transplant patients after age 35 years. However, a larger cohort of patients is necessary to confirm these observations.
Source: Transplantation Proceedings - November 1, 2013 Category: Transplant Surgery Authors: L.C. Kobashigawa, M. Hamilton, M. Rafiei, L. Stern, C.N. Bairey Merz Tags: Thoracic Transplantation Source Type: research

Heart Transplant Outcomes in Patients With Pretransplant Diabetes Mellitus.
CONCLUSIONS: Heart transplant recipients with pretransplant diabetes fared just as well as patients without pretransplant diabetes in 7 of the 8 outcomes examined, except for the number of days hospitalized during the first 3 years after heart transplant. This study provides clinically important new information on the greater hospitalization time and the reasons for hospitalization during the first 3 years after heart transplant in patients with pretransplant diabetes. PMID: 29092871 [PubMed - in process]
Source: American Journal of Critical Care - November 1, 2017 Category: Nursing Authors: Jalowiec A, Grady KL, White-Williams C Tags: Am J Crit Care Source Type: research

Carotid interposition in patients with head and neck tumors: clinical experience of 13 cases reconstructed with a great saphenous vein autograft
CONCLUSION AND SIGNIFICANCE: CIG in HNC setting can achieve oncologic-control with an acceptable rate of complications. Routine shunting, heparinization, and elevating blood-pressure during closure seem to be safe protocols to maintain cerebral-circulation perioperatively. A moderate graft-blowout risk should be considered.PMID:35499961 | DOI:10.1080/00016489.2022.2067356
Source: Cancer Control - May 2, 2022 Category: Cancer & Oncology Authors: Sherif Abolfotouh Leif B äck Katri Aro Patrik Lassus Jyrki Vuola Karri Mesim äki Tommy Wilkman Pirkka Vikatmaa Source Type: research

Do outcomes after kidney transplantation differ for black patients in England versus New York State? A comparative, population-cohort analysis
Conclusions Outcomes after kidney transplantation for black patients may not be translatable between countries.
Source: BMJ Open - May 9, 2017 Category: General Medicine Authors: Tahir, S., Gillott, H., Jackson-Spence, F., Nath, J., Mytton, J., Evison, F., Sharif, A. Tags: Open access, Renal medicine Research Source Type: research

Mortality, rehospitalization, and post-transplant complications in gender-mismatched heart transplant recipients
Conclusion Female HT recipients with male donors had worse 3-year outcomes as compared to male-mismatch and no-mismatch groups.
Source: Heart and Lung: The Journal of Acute and Critical Care - May 10, 2017 Category: Respiratory Medicine Source Type: research

Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTP β/ζ Axis: Relevance in Therapeutic Development
Conclusion The expression of the components of the PTN-MK-RPTPβ/ζ axis in immune cells and in inflammatory diseases suggests important roles for this axis in inflammation. Pleiotrophin has been recently identified as a limiting factor of metainflammation, a chronic pathological state that contributes to neuroinflammation and neurodegeneration. Pleiotrophin also seems to potentiate acute neuroinflammation independently of the inflammatory stimulus while MK seems to play different -even opposite- roles in acute neuroinflammation depending on the stimulus. Which are the functions of MK and PTN in chronic neuroi...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

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