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Total 468 results found since Jan 2013.

Comparison of Clinical Features, Immune-Inflammatory Markers, and Outcomes Between Patients with Acute In-Hospital and Out-of-Hospital Ischemic Stroke
CONCLUSION: Patients with IHIS had more complicated clinical features, higher levels of immune-inflammatory markers, and higher rates of mortality than patients with OHIS. The most significant predictor for mortality among those with OHIS was NIHSS score >10, and the predictors among patients with IHIS were NLR >5.5 and SII >2120.PMID:35177921 | PMC:PMC8843816 | DOI:10.2147/JIR.S342830
Source: Atherosclerosis - February 18, 2022 Category: Cardiology Authors: Pei-Ya Chen Guei-Chiuan Chen Cheng-Lun Hsiao Po-Jen Hsu Fu-Yi Yang Chih-Yang Liu Adam Tsou Wan-Ling Chang Hsiu-Hsun Liu Shinn-Kuang Lin Source Type: research

Circulating CD40+ and CD86+ B Cell Subsets Demonstrate Opposing Associations With Risk of Stroke.
CONCLUSIONS: These observations provide evidence for an involvement of B cells in the incidence of stroke and suggest that both pathogenic and protective B cell subsets exist. PMID: 24202305 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 7, 2013 Category: Cardiology Authors: Mantani PT, Ljungcrantz I, Andersson L, Alm R, Hedblad B, Björkbacka H, Nilsson J, Nordin Fredrikson G Tags: Arterioscler Thromb Vasc Biol Source Type: research

Usefulness of CHADS2 and CHA2DS2-VASc Scores for Stroke Prediction in Patients With Cancer and Atrial Fibrillation
Stroke prediction scores have not been validated in patients with cancer and Atrial Fibrillation (AF). We aimed to identify unique risk factors and evaluate validity of CHADS2 and CHA2DS2-VASc scores to predict risk of stroke and mortality. A retrospective review of all cancer patients with pre-existing AF presenting from 2008 to 2014 was performed. Outcomes included ischemic stroke and mortality. Prognostic factors were identified with Fine& Gray regression for stroke and Cox proportional hazards analysis for survival.
Source: The American Journal of Cardiology - September 19, 2017 Category: Cardiology Authors: Rushad Patell, Alejandra Gutierrez, Lisa Rybicki, Alok A. Khorana Source Type: research

Abstract 14: The Influence of Provider Specialty on Anticoagulation Prescription Fills and Stroke Risk in Atrial Fibrillation Patients With History of Cancer Session Title: Poster Session Reception: Young Investigator Award Semi-Finalists
Conclusion: AF patients with cancer were less likely to see a cardiologist, and less likely to fill an anticoagulant prescription than AF patients without cancer. However, cardiology involvement was associated with increased anticoagulant prescription fills and reduced risk of stroke, suggesting a beneficial role for cardiology providers to improve outcomes in AF patients with history of cancer.
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: ONeal, W. T., Claxton, J., MacLehose, R., Chen, L., Bengtson, L. G., Chamberlain, A. M., Norby, F., Lutsey, P., Alonso, A. Tags: Session Title: Poster Session Reception: Young Investigator Award Semi-Finalists Source Type: research

Edoxaban for the prevention of stroke in patients with atrial fibrillation.
Authors: Cervantes CE, Merino JL, Barrios V Abstract INTRODUCTION: Edoxaban is the last direct oral anticoagulant marketed for the prevention of stroke among patients with nonvalvular atrial fibrillation (AF). Areas covered: ENGAGE AF-TIMI 48 was the pivotal clinical trial that led to the approval of edoxaban 60 mg once daily. After the publication of this study, a great number of substudies and post hoc analyses have been published, together with some observational studies. The aim of this review was to update the current evidence about the use of edoxaban in AF patients. Expert commentary: In the ENGAGE AF-TIMI 4...
Source: Expert Review of Cardiovascular Therapy - March 24, 2019 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Does a History of Cancer Influence the Effectiveness of Statins on Outcomes After Stroke?
CONCLUSIONS: Treatment with statins after ischemic stroke may confer additional survival benefits for people who also have had cancer.PMID:36065808 | DOI:10.1161/STROKEAHA.122.038829
Source: Atherosclerosis - September 6, 2022 Category: Cardiology Authors: Muideen T Olaiya Nadine E Andrew Lachlan L Dalli David Ung Joosup Kim Vijaya Sundararajan Dominique A Cadilhac Amanda G Thrift Mark R Nelson Leonid Churilov Monique F Kilkenny PRECISE Investigators Source Type: research

Diagnostic dilemmas in a patient with multivascular embolic stroke.
We describe a patient admitted to the intensive care unit with aphasia, which was due to an embolic ischaemic cerebral stroke associated with a previously unknown patent foramen ovale. Eventually, this finding during echocardiography led us to the diagnosis of pancreatic cancer. The thrombotic complications of pancreatic cancer, in combination with a large, patent foramen ovale, support the mechanism of a paradoxical embolism through the patent foramen ovale as the cause of cerebral ischaemic stroke. PMID: 26031637 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - June 2, 2015 Category: Cardiology Authors: Delsing CP, van Duijnhoven M, Arnoldussen C, le Noble J Tags: Neth Heart J Source Type: research

Mediterranean Diet in patients with acute ischemic stroke: relationships between Mediterranean diet score, diagnostic subtype, and stroke severity index
Adherence to a Mediterranean Diet appears to reduce the risk of cardiovascular disease, cancer, Alzheimer’s disease, and Parkinson’s disease, as well as the risk of death due to cardiovascular disease. No study has addressed the association between diagnostic subtype of stroke and its severity and adherence to a Mediterranean Diet in subjects with acute ischemic stroke.
Source: Atherosclerosis - September 10, 2015 Category: Cardiology Authors: Antonino Tuttolomondo, Alessandra Casuccio, Carmelo Buttà, Rosaria Pecoraro, Domenico Di Raimondo, Vittoriano Della Corte, Valentina Arnao, Giuseppe Clemente, Carlo Maida, Irene Simonetta, Giuseppe Miceli, Benedetto Lucifora, Anna Cirrincione, Danilo Di Source Type: research

Risk of Cardioembolic Stroke in Cancer Patients with Atrial Fibrillation
In a recent article in the journal, Elbadawi et al1 find that the risk of cerebrovascular accidents (CVA) in cancer patients with atrial fibrillation (AF) was lower than in non-cancer patients with AF. At first glance this may appear surprising in light of the higher risk of stroke of cancer patients generally2,3, particularly those with aggressive subtypes and/or metastatic disease. However, recent studies in patients with AF and cancer4,5 show no increase in stroke risk, seemingly indicating that the risk of cardioembolic stroke specifically is not higher than in cancer-free pacients.
Source: The American Journal of Cardiology - April 18, 2018 Category: Cardiology Authors: Marc Sorigue, Edurne Sarrate, Mireia Franch-Sarto, Juan-Manuel Sancho, Elisa Orna Source Type: research

Risk of Cardioembolic Stroke in Patients With Cancer and Atrial Fibrillation
In a recent article in the journal, Elbadawi et al1 find that the risk of cerebrovascular accidents (CVA) in patients with cancer and atrial fibrillation (AF) was lower than in patients with AF without cancer. At first glance, this may appear surprising in light of the higher stroke risk of patients with cancer in general,2,3 particularly those with aggressive subtypes and/or metastatic disease. However, recent studies in patients with AF and cancer4,5 show no increase in stroke risk, seemingly indicating that the risk of cardioembolic stroke specifically is not higher than in patients without cancer.
Source: The American Journal of Cardiology - April 18, 2018 Category: Cardiology Authors: Marc Sorigue, Edurne Sarrate, Mireia Franch-Sarto, Juan-Manuel Sancho, Elisa Orna Source Type: research

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection —evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology
AbstractDue to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent reperfusion therapy, can wipe out upwards of a billion cardiomyocytes. A similar program of cell death can cause the irreversible loss of neurons in ischaemic stroke. Similar pathways of lethal cell injury can contribute to other pathologies such as left ventricular dysfunction and heart failure caused by cancer therapy. Consequently, strategies designed to protect the ...
Source: Basic Research in Cardiology - October 11, 2018 Category: Cardiology Source Type: research

Po-716-07 is cha2ds2vasc score useful for predicting the risk of stroke in patients with atrial fibrillation and cancer? : a single-center observational analysis
Patients with active cancer were historically excluded from clinical trials validating the CHA2DS2VASc score for stroke prediction in atrial fibrillation (AF). Limited data have questioned the predictive value of the score in patients with cancer and AF, underscoring the need for more personalized scores for prediction of stroke in these patients.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Udhayvir S. Grewal, Mohammad Bhuiyan, Nachiket Madhav APTE, Parinita A. Dherange, Paari Dominic Source Type: research

RPS assessment of research into effects of lycopene on the risk of heart attack, stroke and cancer
Source: Royal Pharmaceutical Society Area: News The Royal Pharmaceutical Society has featured a report on a small study in which scientists claim a single pill which contains a chemical found in tomato skin (lycopene) could cut the risk of heart attacks, stroke and even slow down the development of cancer.   The two-month study looked at 36 patients with pre-existing heart disease, who were already taking cholesterol-lowering statin drugs, and 36 healthy volunteers. Tests showed that the natural remedy boosts the elasticity and efficiency of blood vessels; in turn this reduces the hardening of the arteries which ...
Source: NeLM - Cardiovascular Medicine - January 8, 2013 Category: Cardiology Source Type: news