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Infectious Disease: HIV AIDS
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Total 892 results found since Jan 2013.
Is cervical dysplasia a major concern in women with inflammatory bowel disease? A Spanish retrospective study
Rev Esp Enferm Dig. 2023 Sep 21. doi: 10.17235/reed.2023.9890/2023. Online ahead of print.ABSTRACTCervical cancer (CC) is the fourth most common cancer affecting women worldwide. The risk of women immunosuppressed due to AIDS or organ transplantation is well documented, as most cases are caused by persistent human papillomavirus (HPV) infection and immunosuppression can prevent clearing HPV. Although European guidelines advise that inflammatory bowel disease (IBD) women under immunosuppression should be screened for CC as regularly as high-risk patients, quality evidence is lacking in our country. We performed a retrospect...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lorena Jara Fern ández Juan Ángel Ferrer Jos é Lázaro Pérez Calle Pilar L ópez Serrano Source Type: research
Autophagy in colitis-associated colon cancer: exploring its potential role in reducing initiation and preventing IBD-Related CAC development
Autophagy. 2023 Sep 18. doi: 10.1080/15548627.2023.2259214. Online ahead of print.ABSTRACTColitis-associated colon cancer (CAC) is a distinct form of colorectal cancer that emerges from prolonged colitis in individuals with inflammatory bowel disease (IBD). Chronic inflammation is considered as the most critical contributor to the development and progression of CAC, with the degree and persistence of the inflammatory response being the primary drivers of CAC progression in individuals with IBD. Macroautophagy/autophagy, which is a cellular process that aids in preserving the intestinal mucosal barrier and regulating intest...
Source: Autophagy - September 19, 2023 Category: Cytology Authors: Xuanhong Jin Liangkun You Jincheng Qiao Weidong Han Hongming Pan Source Type: research
Control groups for HIV prevention efficacy trials: what does the future hold?
Curr Opin HIV AIDS. 2023 Sep 12. doi: 10.1097/COH.0000000000000818. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Ending the HIV epidemic will require the development of additional effective immune-mediated and nonimmune-mediated means of HIV prevention. Evaluating novel interventions requires large, controlled trials demonstrating efficacy. Recent advances in the field of HIV prevention necessitate new approaches to efficacy trial design.RECENT FINDINGS: Three classes of efficacy trial designs are possible: standard of prevention-controlled trials, active-controlled trials, and active-controlled trials augmented with e...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Holly Janes Susan Buchbinder Source Type: research
CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research
Antifungal activity of N-arylbenzoquinaldinium derivatives against a clinical strain of M. Canis
Conclusions: N-phenyl-[f]-benzoquinaldinium tetrafluoroborate has been shown as a promising compound for the further development of potent antifungal agents as well as radiotracers for further elucidation of biological pathways of antifungal activity.
Source: Indian Journal of Dermatology - August 31, 2023 Category: Dermatology Authors: Nadezhda E Shchepina Galina A Alexandrova Svetlana Y Balandina Igor I Boiko Sandeep Chaudhary Roman V Shchepin Source Type: research
Cervical cancer screening positivity among women living with HIV in CDC-PEPFAR programs 2018-2022
CONCLUSIONS: These positivity rates are lower than expectations set by the published literature. Further research is needed to determine if these lower rates are attributable to the high level of consistent ART use among these populations, and systematic program monitoring and quality assurance activities are essential to ensure WLHIV have access to the highest possible quality prevention services.PMID:37643419 | DOI:10.1097/QAI.0000000000003286
Source: Cancer Control - August 29, 2023 Category: Cancer & Oncology Authors: Laura J McCormick Steven Gutreuter Oluwatosin Adeoye Sarah X Alger Celeste Amado Zurnaid Bay Catherine Motswere Chirwa Omega Chituwo Della Correia Maria Deus Emilio Dirlikov Tim Efuntoye Laurence Gunde Alinune Kabaghe Julius N Kalamya Cesaltina Lorenzoni Source Type: research
Zwitterionic mesoporous engineering aids peptide-dependent pattern profiling for identification of different liver diseases
Chem Commun (Camb). 2023 Aug 29. doi: 10.1039/d3cc03231k. Online ahead of print.ABSTRACTLiver disease remains a global health challenge, with its incidence steadily increasing worldwide. Herein, zwitterionic mesoporous engineering was developed for the identification of different liver diseases including liver cirrhosis and liver cancer. Based on this engineering, a total of 2633 m/z signals were observed to be enriched. Notably, three key peptides were identified and showed high accuracy and precision for distinguishing the healthy and disease states, propelling the field of nanomedicine toward genuine personalized medici...
Source: Chemical Communications - August 29, 2023 Category: Chemistry Authors: Zixing Xu Wantong Zhang Chunhui Deng Nianrong Sun Source Type: research
The AIDS and Cancer Specimen Resource (ACSR): HIV malignancy specimens and data available at no cost
AIDS Res Ther. 2023 Aug 28;20(1):61. doi: 10.1186/s12981-023-00558-4.ABSTRACTThe goal of the AIDS and Cancer Specimen Resource (ACSR) is to play a major role in the advancement of HIV/AIDS cancer-related research/treatment by providing richly annotated biospecimens and data to researchers at no cost. The ACSR acquires, stores, and equitably distributes these samples and associated clinical data to investigators conducting HIV/AIDS-related research, at no costs. Currently, it is the only biorepository of human biospecimens from people with HIV and cancer available to eligible researchers globally who are studying HIV associ...
Source: AIDS Research and Therapy - August 28, 2023 Category: Infectious Diseases Authors: Sylvia Silver Monika Schmelz Source Type: research
