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Condition: Depression
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Total 5965 results found since Jan 2013.
Regional disparities in suicide among patients with cancer: A nationwide population-based study in Japan
CONCLUSION: The results demonstrated that patients with cancer in certain prefectures in Japan have a high suicide risk.PMID:37737044 | DOI:10.1002/cam4.6574
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Ken Kurisu Saki Harashima Maiko Fujimori Tatsuo Akechi Kazuhiro Yoshiuchi Yosuke Uchitomi Source Type: research
Neuroticism as a moderator of symptom-related distress and depression in 4 noncancer end-of-life populations
The objective of this study was to examine the impact of neuroticism as a moderator of physical symptoms and development of depression in patients with amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), end-stage renal disease (ESRD), and frailty in the last 6 months of life.METHODS: We met this objective using secondary data collected in the Dignity and Distress across End-of-Life Populations study. The data included N = 404 patients with ALS (N = 101), COPD (N = 100), ESRD (N = 101), and frailty (N = 102) in the estimated last 6 months of life, with a range of illness-related symptoms, ass...
Source: Palliative and Supportive Care - September 21, 2023 Category: Palliative Care Authors: Maia S Kredentser Corey S Mackenzie Susan E McClement Murray W Enns Diane Hiebert-Murphy Dallas J Murphy Harvey M Chochinov Source Type: research
Submandibular suction lipectomy and single-hole inflator-free endoscopic thyroidectomy with a submental approach: a new surgical technique
Gland Surg. 2023 Jul 31;12(7):974-981. doi: 10.21037/gs-22-624. Epub 2023 Jun 30.ABSTRACTWe have successfully carried out single-hole inflator-free endoscopic thyroidectomy through a submental approach, which has the advantages of less trauma, fewer complications, and hidden incisions. However, for patients with submandibular fat accumulation, submental incisions are not easy to hide, which directly affects the cosmetic effect. We developed a new surgical strategy "submandibular suction lipectomy and single-hole inflator-free endoscopic thyroidectomy with a submental approach" for these patients. We initially used submandi...
Source: Hand Surgery - September 20, 2023 Category: Surgery Authors: Zhongliang Lang Jing Lv Deling Wu Chunlei Sun Zhiwei Xing Gaoyuan Yu Gongshuai Tao Liping Zhao Xiaopeng Ma Source Type: research
Effectiveness of integrated approach of yoga therapy versus usual care in management on chronic low back pain patients: A randomized controlled pilot study
CONCLUSION: IAYT therapy helped in addressing the psychological components of pain and improved quality of life patients with chronic low back pain compared with usual care.PMID:37724772 | DOI:10.1111/papr.13296
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Spoorthi Poojari Deepanshu Dhiman Babita Ghai Deepali Mathur Kashinath Metri Ketan Kataria Akshay Anand Source Type: research
Exposure to Hazardous Substances and Their Health Effects Among Residents Living Near Three Industrial Waste Incinerators in Korea
CONCLUSION: The possibility of residents in Bugi-myeon being exposed to hazardous substances at incineration facilities cannot be ruled out. To prevent them from further exposure to hazardous substances, it is necessary to prohibit the expansion of additional incineration facilities in this area and to implement continuous monitoring projects for residents.PMID:37724494 | DOI:10.3346/jkms.2023.38.e289
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Sang-Yong Eom Boeun Lee Seonmi Hong Young-Seoub Hong Kyung-Hwa Choi Ho-Jang Kwon Mira Yoon Youn-Seok Kang Jun Hee Lee Yong-Dae Kim Heon Kim Source Type: research
In silico Strategy: A Promising Implement in the Development of Multitarget Drugs against Neurodegenerative Diseases
Curr Top Med Chem. 2023 Aug 31. doi: 10.2174/1568026623666230811113231. Online ahead of print.ABSTRACTMulti-target drug development (MTDD) is the demand of the recent era, especially in the case of multi-factorial conditions such as cancer, depression, neurodegenerative diseases (NDs), etc. The MTDD approaches have many advantages; avoidance of drug-drug interactions, predictable pharmacokinetic profile, and less drug resistance. The wet lab practice in MTDD is very challenging for the researchers, and the chances of late-stage failure are obvious. Identification of an appropriate target (Target fishing) is another challen...
Source: Current Topics in Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Purusottam Banjare Balaji Wamanrao Matore Anjali Murmu Vikash Kumar Jagadish Singh Partha Pratim Roy Source Type: research
Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research
Mechanism Underlying a Brief Cognitive Behavioral Treatment for Head and Neck Cancer Survivors with Body Image Distress
Conclusions: This randomized trial provides preliminary evidence that BRIGHT reduces BID among HNC survivors by decreasing avoidant body image coping. Further research is necessary to confirm these results and enhance the development of interventions targeting relevant pathways to reduce BID among HNC survivors. Trial Registration: This trial was registered on ClinicalTrials.gov identifier NCT03831100 on February 5, 2019.PMID:37720013 | PMC:PMC10503855 | DOI:10.21203/rs.3.rs-3303379/v1
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Evan M Graboyes Emily Kistner-Griffin Elizabeth G Hill Stacey Maurer Wendy Balliet Amy M Williams Lynne Padgett Flora Yan Angie Rush Brad Johnson Taylor McLeod Jennifer Dahne Kenneth J Ruggiero Katherine R Sterba Source Type: research
Programmed Cell Death in Unicellular Versus Multicellular Organisms
Annu Rev Genet. 2023 Sep 18. doi: 10.1146/annurev-genet-033123-095833. Online ahead of print.ABSTRACTProgrammed cell death (self-induced) is intrinsic to all cellular life forms, including unicellular organisms. However, cell death research has focused on animal models to understand cancer, degenerative disorders, and developmental processes. Recently delineated suicidal death mechanisms in bacteria and fungi have revealed ancient origins of animal cell death that are intertwined with immune mechanisms, allaying earlier doubts that self-inflicted cell death pathways exist in microorganisms. Approximately 20 mammalian death...
Source: Annual Review of Genetics - September 18, 2023 Category: Genetics & Stem Cells Authors: Madhura Kulkarni J Marie Hardwick Source Type: research
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder
This study aimed to evaluate the composite mitochondrial health index (MHI) in BD subjects and non-psychiatry controls. We will also explore whether lower MIH will be related to higher cell-free mtDNA (ccf-mtDNA) levels and poor clinical outcomes. In this study, 14 BD-I patients and 16 age- and sex-matched non-psychiatry controls were enrolled. Peripheral blood mononuclear cells (PBMCs) were used to measure the enzymatic activities of citrate synthase and complexes I, II, and IV and mtDNA copy number. Ccf-mtDNA was evaluated by qPCR in plasma. Mitochondrial quality control (MQC) proteins were evaluated by western blotting....
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Rafaela C Cordeiro Camila N C Lima Gabriel R Fries Giovana Zunta-Soares Jair C Soares Jo ão Quevedo Giselli Scaini Source Type: research
Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research
Programmed Cell Death in Unicellular Versus Multicellular Organisms
Annu Rev Genet. 2023 Sep 18. doi: 10.1146/annurev-genet-033123-095833. Online ahead of print.ABSTRACTProgrammed cell death (self-induced) is intrinsic to all cellular life forms, including unicellular organisms. However, cell death research has focused on animal models to understand cancer, degenerative disorders, and developmental processes. Recently delineated suicidal death mechanisms in bacteria and fungi have revealed ancient origins of animal cell death that are intertwined with immune mechanisms, allaying earlier doubts that self-inflicted cell death pathways exist in microorganisms. Approximately 20 mammalian death...
Source: Annual Review of Genetics - September 18, 2023 Category: Genetics & Stem Cells Authors: Madhura Kulkarni J Marie Hardwick Source Type: research
