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Outcome of lung transplant recipients infected with SARS-CoV-2/Omicron/B.1.1.529: a Nationwide German study
ConclusionCOVID-19 due to Omicron remains an important threat for lung transplant recipients. In particular, elderly patients and patients with impaired kidney function are at risk for worse outcome. Prophylaxis and therapy in highly immunocompromised individuals need further improvement.
Source: Infection - September 9, 2022 Category: Infectious Diseases Source Type: research

Analysis of COVID-19 infection in hemodialysis and kidney transplant patients in a pandemic hospital
Conclusions: Increased mortality is expected in both HD and KT patients. Early diagnosis of COVID-19 in those patients with COVID-19 infection can be life-saving.
Source: The Journal of Infection in Developing Countries - June 29, 2022 Category: Infectious Diseases Source Type: research

Clinical Outcomes and Antibody Response in COVID-19–Positive Pediatric Solid Organ Transplant Recipients
We describe the clinical and laboratory manifestations and outcomes of 25 pediatric solid organ transplant recipients who tested positive for severe acute respiratory coronavirus-2. Twenty-one (84%) developed a mild disease; 22 of 23 (96%) had a positive serologic response. Two patients (8%), both kidney transplant recipients with additional comorbidities, developed a severe disease. The findings emphasize the need for close monitoring of this population.
Source: The Pediatric Infectious Disease Journal - November 17, 2021 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Modification of immunosuppressive agents in a kidney transplant recipient with COVID-19 and acute kidney injury
Conclusions: In this case, successful modification of this immunosuppressive regimen was accomplished to reduce drug interaction complications, aiming to avoid calcineurin inhibitor nephrotoxicity while maintaining appropriate levels of immunosuppression to prevent organ rejection and to promote the patient ’s recovery from infection.
Source: The Journal of Infection in Developing Countries - September 29, 2021 Category: Infectious Diseases Source Type: research

COVID-19 after kidney transplantation: Early outcomes and renal function following antiviral treatment
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to ravage the world and claim the lives of thousands of individuals every day. COVID-19 patients may develop different degrees of disease severity, varying from mild forms to critical disease, evolving with acute respiratory distress syndrome, sepsis, and multiorgan failure (Cummings et al., 2020; Karagiannidis et al., 2020). Severe forms result from a combination of the ensuing cytokine storm, the procoagulant state, and the direct viral tropism for various organs.
Source: International Journal of Infectious Diseases - January 13, 2021 Category: Infectious Diseases Authors: Alina Daciana Elec, Mihai Oltean, Patricia Goldis, Cristina Cismaru, Mihaela Lupse, Adriana Muntean, Florin Ioan Elec Source Type: research