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Specialty: International Medicine & Public Health

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Total 9741 results found since Jan 2013.

MERS coronavirus: Candidate vaccine gears up for clinical trials
(Ludwig-Maximilians-Universität München) Researchers from Ludwig-Maximilians-Universitaet in Munich have demonstrated, in a preclinical setting, the protective effect of a candidate vaccine directed against the coronavirus that causes Middle East Respiratory Syndrome. Planning for the first clinical trial is now underway.
Source: EurekAlert! - Medicine and Health - June 22, 2015 Category: Global & Universal Source Type: news

Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea, 2015
The outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the Republic of Korea started from the index case who developed fever after returning from Middle East. He infected 26 cases in Hospital C, and consecutive nosocomial transmission proceeded throughout the nation. We provide an epidemiologic description of the outbreak, as of July 2015.
Source: Osong Public Health and Research Perspectives - September 5, 2015 Category: Global & Universal Authors: Seung Woo Kim, Tae Un Yang, Yoolwon Jeong, Jung Wan Park, Keon-Joo Lee, Kyung Min Kim, Jongseok Oh, Yong-shik Park, Woncheol Lee, Jong Rak Jung, Changhwan Lee, Joonkee Lee, Heun Choi, WooSuck Suh, Dae-Won Kim, Hoon gil Jo, Minsung Kim, Jungmo Ahn, Kanghyo Tags: Original Article Source Type: research

Implementation of Quaternary Prevention in the Korean Healthcare System: Lessons From the 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea.
Authors: Bae JM Abstract Quaternary prevention should be implemented to minimize harm to patients because the ultimate goal of medicine is to prevent disease and promote health. Primary care physicians have a major responsibility in quaternary prevention, and the establishment of clinical epidemiology as a distinct field of study would create a role charged with minimizing patient harm arising from over-medicalization. PMID: 26639739 [PubMed - in process]
Source: Journal of Preventive Medicine and Public Health - December 10, 2015 Category: Global & Universal Tags: J Prev Med Public Health Source Type: research

The Characteristics of Middle Eastern Respiratory Syndrome Coronavirus Transmission Dynamics in South Korea
The outbreak of Middle Eastern respiratory syndrome coronavirus (MERS-CoV) was one of the major events in South Korea in 2015. In particular, this study pays attention to formulating a mathematical model for MERS transmission dynamics and estimating transmission rates of both hospitalized patients and the overall population.
Source: Osong Public Health and Research Perspectives - January 18, 2016 Category: Global & Universal Authors: Yunhwan Kim, Sunmi Lee, Chaeshin Chu, Seoyun Choe, Saeme Hong, Youngseo Shin Tags: Original article Source Type: research

WHO (World Health Organization)'s High-Level Mission to Saudi Arabia on Middle East Respiratory Syndrome Coronavirus (MERS-CoV) 11-14 January 2016
World Health Organization, Regional Office for the Eastern Mediterranean. 01/26/2016This Web page provides a summary of a World Health Organization (WHO) mission conducted in Saudi Arabia from January 11-14, 2016, to review the ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) situation, and assess progress in implementing previous mission recommendations. Participants met to identify main areas of public health research to better address remaining knowledge gaps, and agree on a joint operational plan for WHO and the Ministry of Health of Saudi Arabia for collaborative work and research to prevent and control MERS-CoV. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - January 28, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news

Proceedings of the Middle East Respiratory Syndrome (MERS) Coronavirus research initiative workshop, September 9–10 2015 in Riyadh, KSA
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was identified in Saudi Arabia in 2012. More than 1600 cases in 26 countries have been reported to date [1]. Many patients become critically ill, with a reported mortality of up to 70% among MERS CoV patients who require intensive care admission [2]. Hospital-based outbreaks have occurred mainly in the KSA. Outside of the KSA, South Korea experienced the second largest described outbreak. The outbreak, which originated from a single index case who had a history of travel to the Middle East, spread to several acute care facilities [3,4].
Source: Journal of Infection and Public Health - March 28, 2016 Category: Global & Universal Authors: Yaseen M. Arabi, Rob Fowler, Hanan H. Balkhy Tags: Editorial Source Type: research

Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus
Nitazoxanide is a broad-spectrum antiviral agent undergoing clinical development for treatment of influenza and other viral respiratory infections. Nitazoxanide exhibits in vitro activity against Middle East respiratory syndrome coronavirus (MERS-CoV) and other coronaviruses, inhibiting expression of the viral N protein. Nitazoxanide also suppresses production of pro-inflammatory cytokines in peripheral blood mononuclear cells and suppresses interleukin 6 production in mice. Having been used extensively in clinical trials and in post-marketing experience, nitazoxanide is an attractive drug candidate for treatment of Middle...
Source: Journal of Infection and Public Health - April 15, 2016 Category: Global & Universal Authors: Jean-François Rossignol Source Type: research

Clinical spectrum of the Middle East respiratory syndrome coronavirus (MERS-CoV)
Middle East respiratory syndrome coronavirus (MERS-CoV) was first recognized as a cause of severe acute respiratory infection in the Kingdom of Saudi Arabia in 2012. As of February 2, 2016, 1638 laboratory-confirmed cases have been reported to the World Health Organization, including at least 587 deaths [1]. While MERS-CoV has affected 26 countries, the majority of cases have been reported in the Middle East [2]. Transmission has most commonly been associated with nosocomial outbreaks [3–7] and is occasionally due to animal-to-human (most commonly camel-to-human) transmission and sporadic human-to-human transmission in t...
Source: Journal of Infection and Public Health - April 28, 2016 Category: Global & Universal Authors: Mikiko Senga, Yaseen M. Arabi, Robert A. Fowler Source Type: research

Tools for Preparedness: Triage, Screening and Patient Management for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infections in Acute Care Settings
Public Health Ontario. 07/2015This 19-page document of tools is intended to assist frontline healthcare workers (primarily in Emergency Departments, although the principles are applicable in other urgent care settings) in the identification and immediate management of patients who present with severe acute respiratory infection that may be due to Middle East respiratory syndrome coronavirus (MERS-CoV). It provides checklists, guidelines, and algorithms. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - May 5, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news

Human coronavirus and severe acute respiratory infection in Southern Brazil.
This study aimed to analyze the impact of HCoV infections and their relation to severe acute respiratory infection (SARI) in a hospitalized population in Southern Brazil. A cross-sectional study was conducted at a tertiary care hospital, and assessed inpatients under investigation for SARI by the hospital epidemiology department, and all patients who had nasopharyngeal aspirates collected from January 2012 to December 2013 to detect respiratory viruses (RVs). Viral infection was detected by multiplex reverse transcriptase polymerase chain reaction (RT-PCR), with primers specific to the subtypes HCoV-229E/NL63 and OC43/HKU1...
Source: Pathogens and Global Health - May 21, 2016 Category: Global & Universal Tags: Pathog Glob Health Source Type: research

Biosafety Advisory: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Public Health Agency of Canada. 07/07/2015This biosafety advisory is provided by the Public Health Agency of Canada to assist laboratories in implementing proper biosafety procedures when handling samples containing Middle East respiratory syndrome coronavirus (MERS-CoV). It provides biosafety requirements, non-propagative clinical/diagnostic activities, and transportation guidance. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - June 23, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news

Clinical spectrum of the Middle East respiratory syndrome coronavirus (MERS-CoV)
Middle East respiratory syndrome coronavirus (MERS-CoV) was first recognized as a cause of severe acute respiratory infection in the Kingdom of Saudi Arabia in 2012. As of February 2, 2016, 1638 laboratory-confirmed cases have been reported to the World Health Organization, including at least 587 deaths [1]. While MERS-CoV has affected 26 countries, the majority of cases have been reported in the Middle East [2]. Transmission has most commonly been associated with nosocomial outbreaks [3 –7] and is occasionally due to animal-to-human (most commonly camel-to-human) transmission and sporadic human-to-human transmission in ...
Source: Journal of Infection and Public Health - April 28, 2016 Category: Global & Universal Authors: Mikiko Senga, Yaseen M. Arabi, Robert A. Fowler Source Type: research

New episode of Middle East Respiratory Syndrome Coronavirus outbreak in Saudi Arabia: an emerging public health threat
Over the last five years, Middle East respiratory syndrome coronavirus (MERS-CoV) infection has emerged as a devastating public health menace.1 The causative agent of infection is a newly defined, positive-sense, single-stranded RNA virus of the genus Betacoronavirus. Major signs and symptoms of MERS-related illness include fever, cough, shortness of breath, and respiratory complications. The first report of this novel viral infection came from Saudi Arabia in 2012.1 The United Arab Emirates, Jordan, Oman, Qatar, and South Korea currently top the list of nations with verified incidence of disease.
Source: Public Health - August 9, 2017 Category: International Medicine & Public Health Authors: Abdul Waheed Khan, Andrew W. Taylor-Robinson, Zeeshan Nasim, Fazli Zahir, Abid Ali, Shahid Ali Tags: Short Communication Source Type: research

Knowledge and attitude towards the Middle East respiratory syndrome coronavirus among healthcare personnel in the southern region of Saudi Arabia
Middle East respiratory syndrome coronavirus (MERS-CoV) belongs to the family Coronaviridae, and is named for the crown-like spikes on its surface. The clinical presentation of MERS-CoV infection ranges from asymptomatic to very severe disease, and the classical presentation includes fever, cough chills, sore throat, myalgia, and arthralgia.
Source: Journal of Infection and Public Health - March 8, 2018 Category: International Medicine & Public Health Authors: Huda F. Abbag, Awad Ahmed El-Mekki, Ali Aobaid Ali Al Bshabshe, Ahmed A. Mahfouz, Ahasen A. Al-Dosry, Rasha T. Mirdad, Nora F. AlKhttabi, Lubna F. Abbag Source Type: research