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Impact of In-hospital Statin Use on Mortality in COVID-19 Patients from a Majority African American Population
Coronavirus Disease 2019 (COVID-19) was declared a worldwide pandemic by the World Health Organization on March 11, 2020.1 As of August 18th, 2022, the pandemic has claimed over 6,400,000 lives worldwide and over 1,000,000 lives in the United States according to the Johns Hopkins Coronavirus Resource Center.2 The virus works primarily by binding to angiotensin-converting receptor 2 on alveolar epithelial cells, whereby it activates the innate and adaptive immune systems and results in inflammation caused by a pro-inflammatory cytokine storm.
Source: Heart and Lung - March 12, 2023 Category: Intensive Care Authors: Nitish Sood, Dhairya Shukla, Pranjal Mishra, Saloni Sharma, Sahil Gandhi, Daniel F. Linder, Priyank Shah Source Type: research

The advantages of drug treatment with statins in patients with SARS-CoV-2 infection
Wien Klin Wochenschr. 2021 Mar 29. doi: 10.1007/s00508-021-01845-8. Online ahead of print.ABSTRACTOn 11 March 2020 the World Health Organization (WHO) declared a status of global pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019, COVID-19). The pandemic is currently underway, and to date has caused approximately 2.42 million deaths worldwide. The first vaccines have recently been licensed; however, research continues to identify therapeutic agents to prevent serious complications, such as anti-inflammatory, immunomodulatory, anticoagulant or antiviral agents a...
Source: Wiener Klinische Wochenschrift - March 29, 2021 Category: General Medicine Authors: Francesco Ferrara Antonio Vitiello Source Type: research

Fight Aging! Newsletter, February 22nd 2021
In conclusion, long term LRIC could decrease blood pressure and ameliorate vascular remodeling via inflammation regulation. The Damage of a Heart Attack Causes the Immune System to Overreact https://www.fightaging.org/archives/2021/02/the-damage-of-a-heart-attack-causes-the-immune-system-to-overreact/ Researchers here note a mechanism that causes T cells of the adaptive immune system to spur chronic inflammation and tissue damage following a heart attack. As the researchers note, not all inflammation is the same. Some is maladaptive, and this is particularly the case in older individuals. The aged immune...
Source: Fight Aging! - February 21, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs