Fight Aging! Newsletter, February 22nd 2021

In conclusion, long term LRIC could decrease blood pressure and ameliorate vascular remodeling via inflammation regulation. The Damage of a Heart Attack Causes the Immune System to Overreact https://www.fightaging.org/archives/2021/02/the-damage-of-a-heart-attack-causes-the-immune-system-to-overreact/ Researchers here note a mechanism that causes T cells of the adaptive immune system to spur chronic inflammation and tissue damage following a heart attack. As the researchers note, not all inflammation is the same. Some is maladaptive, and this is particularly the case in older individuals. The aged immune system is more prone to a sustained inflammatory response, provoked by pro-inflammatory signaling of senescent cells and the signs of cell damage that circulate in the body. Suppressing all inflammation is too blunt of a tool, however, as short-term inflammation is still necessary for regeneration and response to pathogens even in later life. Inflammation is supposed to help protect us - it's part of an immune response to fight off pathogens and clear infections. But patients with cardiac disease often have chronic inflammation that damages their hearts, even with no infection present. When a heart attack or other issue damages the heart and leaves it unable to pump enough blood to meet the body's needs, the heart tries to compensate by pumping faster. The cardiac muscle cells have to work harder and this stress causes them to release molecules kn...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs