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Corticosteroid effectiveness among hospitalised COVID-19 patients in Malaysia
Conclusions: This study concludes that using low-dose corticosteroids is recommended for hospitalised COVID-19 patients to ensure clinical outcomes are optimised.
Source: The Journal of Infection in Developing Countries - September 29, 2022 Category: Infectious Diseases Source Type: research

The Outcome of High-Dose Corticosteroid Treatment Among Coronavirus Disease 2019 Patients: A Retrospective Cohort Study
This study aimed to demonstrate the association between high-dose corticosteroid administration and adverse outcomes in coronavirus disease 2019 patients. Data were collected retrospectively from medical records. The primary outcome was invasive mechanical ventilation or death, whichever occurred first. The secondary outcome was all-cause in-hospital mortality. The standard dose was defined as a daily dose of ≤1.5 mg/kg of prednisolone or equivalent, and the high-dose was defined as ≥250 mg of prednisolone or equivalent. Data were analyzed using frequentist and Bayesian logistic models. In addition, a propensity scoreâ...
Source: Infectious Diseases in Clinical Practice - September 1, 2022 Category: Infectious Diseases Tags: Original Article Source Type: research

Multisystem Inflammatory Syndrome in Children: Follow-Up of a Cohort from North India
This study was conducted to describe the long-term outcome of MIS-C from a tertiary care center in North India. Children admitted with MIS-C from September 2020 to January 2021 were followed up after discharge until June 2021. The details during the acute phase (clinical features, investigations, treatment, and outcome) and follow-up (symptoms, echocardiographic findings, ongoing treatment, and outcome) were collected retrospectively. During the acute phase, 40 children presented at median (interquartile range [IQR]) age of 7 (5-10) years with fever, mucocutaneous, gastrointestinal, and respiratory symptoms. The majority (...
Source: Am J Trop Med Hyg - February 16, 2022 Category: Infectious Diseases Authors: Puspraj Awasthi Vijay Kumar Sanjeev Naganur Karthi Nallasamy Suresh Kumar Angurana Arun Bansal Rohit Kumar Manoj Muralidharan Jayashree Source Type: research

Epidemiologic and clinical characteristics of multisystem inflammatory syndrome in adults: a rapid review
Can Commun Dis Rep. 2021 Jul 8;47(7-8):305-315. doi: 10.14745/ccdr.v47i78a03. eCollection 2021 Jul 8.ABSTRACTMultisystem inflammatory disease in children (MIS-C) is one of the severe presentations of the coronavirus disease 2019 (COVID-19) that has been described in the literature since the beginning of the pandemic. Although MIS-C refers to children, cases with similar clinical characteristics have been recently described in adults. A description of the epidemiologic and clinical characteristics of multisystem inflammatory disease in adults (MIS-A) is a starting point for better knowledge and understanding of this emergin...
Source: Can Commun Dis Rep - August 23, 2021 Category: Infectious Diseases Authors: Nicole Atchessi Rojiemiahd Edjoc Megan Striha Lisa Waddell Natalie Bresee Thomas Dawson Source Type: research

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