Personalizing the first dose of FSH for IVF/ICSI patients through machine learning: a non-inferiority study protocol for a multi-center randomized controlled trial
This study will be performed in 236 first cycle in vitro fertilization (IVF) and/or ICSI (intracytoplasmic sperm injection) patients, randomized 1:1 in two arms. In the intervention arm, the dose of FSH will be assigned by a machine learning (ML) model called IDoser, while in the control arm, the dose will be determined by the clinician following standard practice. Stratified block randomization will be carried out depending on the patient being classified as expected low responder, high responder, or normo-responder. Patients will complete their participation in the trial once the first embryo transfer result is known. Th...
Source: Trials - January 11, 2024 Category: Research Source Type: clinical trials

REFLECT: Reproductive Education and Fertility Links for Cancer Treatment
Conditions: Reproductive Behavior Interventions: Behavioral: REFLECT web-based tool Sponsors: H. Lee Moffitt Cancer Center and Research Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

Marius Pharmaceuticals Announces Pilot Study Exploring the Effect of Its Oral Testosterone Therapy, KYZATREX on Male Fertility
RALEIGH, N.C., Jan. 9, 2024. Marius Pharmaceuticals a pharmaceutical company focused on developing innovative therapies for testosterone deficiency, today announced it has initiated a pilot study to better understand the effect of... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - January 9, 2024 Category: Pharmaceuticals Source Type: clinical trials

TRAP Study: Testosterone for Androgen Receptor Polymorphism
Conditions: Fertility Disorders Interventions: Drug: Transdermal Gel in Sachet Dosage Form; Drug: No pretreatment Sponsors: Instituto Bernabeu Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials

Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)
Conditions: Fertility Issues Sponsors: Bar-Chama, Natan, M.D. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials

Usefulness of Corifollitropin α as Alternative to Conventional Daily rFSH Protocols in Oocyte Donors Undergoing Pituitary Suppression With Medroxiprogesterona Acetate (MPA)
Conditions: Infertility, Female; Reproductive Sterility Interventions: Drug: Corifolitropin Alfa; Drug: Folitropin Beta Sponsors: Instituto Valenciano de Infertilidad, IVI VALENCIA Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials

Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients
Conditions: Urologic Diseases; Male Infertility; Sexual Medicine Interventions: Other: Observation during time Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials

Bank of Biological Material From Patients and Healthy Donors for the Study of Urological and Uro-oncological Pathologies
Conditions: Urologic Diseases; Urologic Cancer; Infertility Interventions: Other: Collection of biological data Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Conditions: Hypoxia; Hysteroscopy; Overweight or Obesity Interventions: Drug: remimazolam; Drug: Propofol Sponsors: RenJi Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Home Semen Analysis Tests as a Screening Tool for Fertility Patients
Conditions: Male Infertility Interventions: Device: ExSeed ®; Other: Survey Sponsors: University of Aberdeen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Creation of a Biobank of Fertile Men
Conditions: Fertility Interventions: Other: Observation of biological characteristics of fertile men Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

" System Medicine " Approach for Prevention Strategies for Comorbidities in Infertile Men
Conditions: Infertility; Male Infertility Interventions: Other: Observation and evaluation of clinical parameters in the two cohorts Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

The Effect of Motivational Interviews
Conditions: Infertility, Female Interventions: Other: Motivational Interview Sponsors: Kahramanmaras Sutcu Imam University Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials

Endometrial Preparation in Frozen Embryo Transfer Cycles
Conditions: IVF Interventions: Drug: estradiol valerate and letrozole; Drug: letrozole 2,5 mg tablet Sponsors: Rahem Fertility Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials

2015-Metabolomics & Microbiome-infertility
Conditions: Azoospermia, Nonobstructive Interventions: Other: Analysis of microbiome and metabolomics Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials