Limited Competition: Rare Diseases Clinical Research Network (RDCRN) Project Supplements for Clinical Trials to Repurpose Drugs in Collaboration with E-Rare Awardees (Admin Supp)
Funding Opportunity PA-16-183 from the NIH Guide for Grants and Contracts. This funding opportunity is intended to provide support through an administrative supplement to existing Rare Diseases Clinical Research Network (RDCRN) awardees whose projects encompass the implementation of clinical trials. Through this supplement, NCATS intends to provide support for phase 1 and/or 2 clinical trial sites that will test the potential use of an existing molecule for the treatment of a rare disease as part of a multi-site international E-Rare-3 trial. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 12, 2016 Category: Research Source Type: funding
Natural History Studies for Rare Disease Product Development: Orphan Products Research Project Grant (R01)
The objective of FDA's Orphan Products Natural History Grants Program is to support studies that advance rare disease medical product development through characterization of the natural history of rare diseases/conditions, identification of genotypic and phenotypic subpopulations, and development and/or validation of clinical outcome measures, biomarkers and/or companion diagnostics. The ultimate goal of these natural history studies is to support clinical development of products for use in rare diseases or conditions where no current therapy exists or where the proposed product will be superior to the existing therapy. FD...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 11, 2016 Category: Research Source Type: funding
Limited Competition: Tissue Chips for Rare Diseases (Admin Supp)
Funding Opportunity Number: PA-16-173 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: HealthCFDA Number: 93.350Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, ...
Source: Grants.gov - April 9, 2016 Category: Research Tags: Health Source Type: funding
Limited Competition: Tissue Chips for Rare Diseases (Admin Supp)
Funding Opportunity PA-16-173 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is for investigators and institutions currently funded through the NIH Tissue Chip (TC) Program to request supplemental funding that will be used to create and test tissue devices relating to rare diseases utilizing the Rare Diseases Clinical Research Network (RDCRN), http://www.rarediseasesnetwork.org. This limited competition invites applicants and awardees funded under RFA-RM-11-022 "Integrated Microphysiological Systems for Drug Efficacy and Toxicity Testing in Human Health and Disease (UH2/UH3)" (So...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 8, 2016 Category: Research Source Type: funding
Investigator Initiated Multi-Site Clinical Trials (Collaborative R01)
Funding Opportunity Number: PAR-13-128 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: HealthCFDA Number: 93.23393.83793.83893.839Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) st...
Source: Grants.gov - February 5, 2016 Category: Research Tags: Health Source Type: funding
Setting the Course for Scientific Discovery
The objectives align with many familiar themes for readers of this blog:
advance opportunities in biomedical research in fundamental science, treatment and cures, and health promotion and disease prevention
foster innovation by setting NIH priorities to enhance nimbleness, consider burden of disease and value of permanently eradicating a disease, and advance research opportunities presented by rare diseases
enhance scientific stewardship by recruiting and retaining an outstanding biomedical research workforce, enhancing workforce diversity and impact through partnerships, ensuring rigor and reproducibility, optimizing app...
Source: NIH Extramural Nexus - December 21, 2015 Category: Research Authors: Mike Lauer Tags: blog Open Mike General strategic plan Source Type: funding
An Opportunity to Collaborate and Use the Unique Resources of the NIH Clinical Center
Three years ago, NIH created a program to enable extramural researchers to collaborate with our intramural scientists and use the exceptional resources of the NIH Clinical Center. Since then, 20 awards have been made to support projects of significant breadth, such as a trial for treatment of relapsed leukemia; a malaria vaccine trial; and a trial testing a new cardiac catheter. This is the fourth year that NIH has issued this funding opportunity. The December 15 pre-application deadline is approaching, and I wanted to remind you what this program offers.
As described in the funding opportunity announcements (FOAs) (PAR 15...
Source: NIH Extramural Nexus - November 18, 2015 Category: Research Authors: Mike Lauer Tags: blog Open Mike Award Programs Clinical Center Source Type: funding
Clinical Trial Readiness for Rare Neurological and Neuromuscular Diseases (U01)
Funding Opportunity Number: PAR-16-020 Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCFDA Number: 93.853Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) stat...
Source: Grants.gov - October 30, 2015 Category: Research Tags: Health Source Type: funding
Clinical Trial Readiness for Rare Neurological and Neuromuscular Diseases (U01)
Funding Opportunity PAR-16-020 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support clinical studies that will fill gaps in the design of upcoming clinical trials in rare neurological or neuromuscular diseases by validating clinical outcome measures or biomarkers, or by characterizing cohorts of relevant patients.Through the support of trial readiness studies, NINDS expects to accelerate the initiation of clinical trials for rare diseases and to increase the likelihood of success in those trials. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 29, 2015 Category: Research Source Type: funding
Research and Methods in Health Statistics
Funding Opportunity Number: RFA-SH-16-001 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: HealthCFDA Number: 93.061Eligible Applicants Others (see text field entitled "Additional Information on Eligibility" for clarification)Agency Name: HHS-CDC-HHSCDCERAClosing Date: Oct 07, 2015Award Ceiling: $100,000Expected Number of Awards: 4Creation Date: Jul 23, 2015Funding Opportunity Description: Research and Methods in Health Statistics Purpose This initiative invites investigator-initiated research grant applications for projects involvin...
Source: Grants.gov - July 24, 2015 Category: Research Tags: Health Source Type: funding
Burden of Disease and NIH Funding Priorities
Dr. Carrie Wolinetz is NIH’s Associate Director for Science Policy, and writes about biomedical research policy issues on her new blog, Under the Poliscope.
Recently, many voices have asked how NIH considers public health needs when setting funding priorities. The quick answer is that public health needs are a critical factor in our decision making—in addition to scientific merit, portfolio balance, and budgetary considerations. But the question of how one measures public health need, as it turns out, isn’t as simple as you might think.
Public health needs are not only reflected by how many people have a particular d...
Source: NIH Extramural Nexus - June 19, 2015 Category: Research Authors: Sally Rockey and Carrie Wolinetz Tags: Rock Talk disease burden Funding data RCDC RePORT Science policy Source Type: funding
Undiagnosed Diseases Gene Function Research (R21)
Funding Opportunity Number: RFA-RM-15-004 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: HealthCFDA Number: 93.310Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the I...
Source: Grants.gov - April 17, 2015 Category: Research Tags: Health Source Type: funding
Undiagnosed Diseases Gene Function Research (R21)
Funding Opportunity RFA-RM-15-004 from the NIH Guide for Grants and Contracts. Diseases Network (UDN) building upon the NIH Intramural Research Programs Undiagnosed Diseases Program (NIH-UDP). Responsive applications will propose to investigate the underlying genetics, biochemistry and/or pathophysiology of newly diagnosed diseases in association with the respective gene variant(s) identified through the UDN. In recent years, gene function studies combined with genetic and genomic analyses and metabolic studies have greatly improved diagnoses of these very rare diseases and advanced scientific knowledge of the underl...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 16, 2015 Category: Research Source Type: funding
Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01)
Funding Opportunity Number: RFA-FD-15-001 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Business and CommerceCommunity DevelopmentConsumer ProtectionEducationEnvironmentFood and NutritionHealthNatural ResourcesScience and Technology and other Research and DevelopmentCFDA Number: 93.103Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing a...
Source: Grants.gov - December 9, 2014 Category: Research Tags: Business and Commerce Community Development Consumer Protection Education Environment Food and Nutrition Health Natural Resources Science and Technology and other Research and Development Source Type: funding
Request for Proposals: National Tay-Sachs & Allied Diseases Association Research Grant Program
Request for Proposals: National Tay-Sachs & Allied Diseases Association Research Grant Program The National Tay- Sachs & Allied Diseases Association Inc. (NTSAD) is considered to be the nation’s oldest genetic disease nonprofit organization. The “Allied Diseases” represent a family of almost 100 rare diseases including lysosomal storage diseases (LSD) and leukodystrophies affecting the central nervous system. A major element of NTSAD’s mission is to lead the fight to treat and cure Tay-Sachs, Canavan and related genetic diseases; therefore, NTSAD is committed to funding research pr...
Source: ScanGrants feed - December 9, 2014 Category: Research Authors: National Tay-Sachs & Allied Diseases Association Source Type: funding
