IJERPH, Vol. 19, Pages 12920: Inhibition of LPS-Induced Microglial Activation by the Ethyl Acetate Extract of Pueraria mirifica
This study aimed to explore the anti-inflammatory effect of the ethyl acetate extract of Pueraria mirifica on microglial activation. Lipopolysaccharide (LPS)-induced inflammation was used as a model to investigate the effects of P. mirifica on HAPI (highly aggressive proliferating immortalized), a rat microglial cell line. Administration of ethyl acetate extract from the tuberous roots of P. mirifica to HAPI cells dose-dependently reduced NO production and iNOS expression induced by LPS. Attenuation of IRF-1 (interferon regulatory factor-1) induction, one of the transcription factors governing iNOS expression, suggested th...
Source: International Journal of Environmental Research and Public Health - October 9, 2022 Category: Environmental Health Authors: Nattinee Jantaratnotai Anusorn Thampithak Pongsak Utaisincharoen Darawan Pinthong Pimtip Sanvarinda Tags: Article Source Type: research
Comparison of neuroprotective effects of dihydrotestosterone, 17 β-estradiol, and Pueraria mirifica herb extract on cognitive impairment in androgen deficient male rats
In conclusion, DHT showed a stronger efficacy for mitigation of the impaired spatial learning behavior and memory capacity in androgen-deficient male rats compared to E2 and PME, and their mechanisms of action are slightly different.PMID:35609404 | DOI:10.1016/j.yhbeh.2022.105198 (Source: Hormones and Behavior)
Source: Hormones and Behavior - May 24, 2022 Category: Endocrinology Authors: Taratorn Fainanta Sukanya Jaroenporn Patteera Wititsuwankul Suchinda Malaivijitnond Source Type: research
Comparison of neuroprotective effects of dihydrotestosterone, 17 β-estradiol, and Pueraria mirifica herb extract on cognitive impairment in androgen deficient male rats
In conclusion, DHT showed a stronger efficacy for mitigation of the impaired spatial learning behavior and memory capacity in androgen-deficient male rats compared to E2 and PME, and their mechanisms of action are slightly different.PMID:35609404 | DOI:10.1016/j.yhbeh.2022.105198 (Source: Hormones and Behavior)
Source: Hormones and Behavior - May 24, 2022 Category: Endocrinology Authors: Taratorn Fainanta Sukanya Jaroenporn Patteera Wititsuwankul Suchinda Malaivijitnond Source Type: research
Recognition and Prevalence of "Designated Ingredient, etc." in Health Foods
In conclusion, the recognition of "designated ingredient, etc." is insufficient. To avoid adverse events associated with "food containing designated ingredient, etc.," detailed information should be provided.PMID:35264518 | DOI:10.3358/shokueishi.63.20 (Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - March 10, 2022 Category: Food Science Authors: Tsuyoshi Chiba Nanae Tanemura Chiharu Nishijima Keizo Umegaki Source Type: research
