What Causes Muscle Weakness?
Discussion
Muscle tone is the slight tension that is felt in a muscle when it is voluntarily relaxed. It can be assessed by asking the patient to relax and then taking the muscles through a range of motion such as moving the wrists, forearm and upper arm. Muscle strength is the muscle’s force against active resistance. Impaired strength is called weakness or paresis. There are 5 levels of muscle strength.
0 = No muscle contraction detected
1 = Barely detected flicker of contraction
2 = Active movement with gravity eliminated
3 = Active movement against gravity
4 = Active movement against gravity and some resistance
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Source: PediatricEducation.org - December 9, 2013 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
'We're worried he might eat himself to death': Toddler has rare genetic condition which means he is always hungry
Geezer Buxton, from Chesterton, Stafforshire, is one of a handful of youngsters in the country to be diagnosed with Prader-Willi syndrome. (Source: the Mail online | Health)
Source: the Mail online | Health - November 18, 2013 Category: Consumer Health News Source Type: news
Gene pinpointed in Prader-Willi syndrome
As so many genome studies do, this study published online in the journal Nature Genetics began with a single patient and his parents who were in search of a diagnosis. The parents of this first patient sought genetic testing for Prader-Willi syndrome when he was only a year old, but the test, which was still in its infancy, came back negative. For the next 12 years, his parents were left in limbo. He had many features of the disease - including lack of muscle tone, feeding difficulties and failure to thrive early on... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 1, 2013 Category: Consumer Health News Tags: Autism Source Type: news
Sequencing studies help pinpoint gene in Prader-Willi syndrome
(Source: Baylor College of Medicine News)
Source: Baylor College of Medicine News - September 29, 2013 Category: Universities & Medical Training Source Type: news
Sequencing studies help pinpoint gene in Prader-Willi syndrome
(Baylor College of Medicine) As so many genome studies do, this study published online in the journal Nature Genetics began with a single patient and his parents who were in search of a diagnosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2013 Category: Global & Universal Source Type: news
Exploring patterns of unwanted behaviours in adults with Prader-Willi syndrome - Pignatti R, Mori I, Bertella L, Grugni G, Giardino D, Molinari E.
BACKGROUND: Obsessive-compulsive (O-C) traits, and excessive food intake are well known behavioural manifestations among individuals with Prader-Willi Syndrome (PWS). Other unwanted behaviours are also frequently observed, but they need a more specific inv... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 20, 2013 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news
Interference In Circadian, Metabolic Genes May Cause Symptoms Of Prader-Willi Syndrome
Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome - a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity - is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep. The research was led by Janine LaSalle, a professor in the UC Davis Department of Medical Microbiology and Immunology who is affiliated with the MIND Institute... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 28, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news
Symptoms of Prader-Willi syndrome associated with interference in circadian, metabolic genes
(University of California - Davis Health System) Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome -- a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity -- is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 25, 2013 Category: Global & Universal Source Type: news
Variants in the SIM1 gene are associated with severe obesity (EurekAlert, 17 June 2013)
Two international studies published in the Journal of Clinical Investigation identify rare obesity-linked mutations in the gene SIM1. One of the studies also links certain mutations with severe obesity associated with, or independent of, Prader-Willi–like features.
Full article (Source: Society for Endocrinology)
Source: Society for Endocrinology - June 18, 2013 Category: Endocrinology Source Type: news
The girl who could eat herself to death: Ava, 5, has to be locked out of the kitchen due to condition that makes her constantly hungry
Ava Carvey, five, from Bromley, was diagnosed with Prader-Willi syndrome when she was nine-weeks-old. She is constantly hungry and would eat until she was sick if allowed uncontrolled access to food. (Source: the Mail online | Health)
Source: the Mail online | Health - April 29, 2013 Category: Consumer Health News Source Type: news
Genetic Connections Identified In 15q Duplication Syndrome/Autism
A new study published in the March issue of Autism Research from the University of Tennessee Health Science Center and Le Bonheur researchers is making the genetic connections between autism and Chromosome 15q Duplication Syndrome (Dup15q). The Memphis researchers determined that the maternally derived or inherited duplication of the region inclusive of the UBE3A gene (also known as the Angelman/Prader-Willi syndrome locus) are sufficient to produce a phenotype on the autism spectrum in all ten maternal duplication subjects... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 28, 2013 Category: Consumer Health News Tags: Autism Source Type: news
