Mechanistic and Hemodynamic Basis of Diffuse White Matter Disease in Vascular Contributions to Cognitive Impairment and Dementia (VCID)(R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-196 from the NIH Guide for Grants and Contracts. (Reissue of RFA-NS-16-021, PAR-18-413, RFA-NS-19-039) Diffuse brain white matter disease is highly prevalent in the elderly, and has been clinically associated with vascular contributions to cognitive impairment and dementia (VCID) in both men and women. Diffuse white matter disease is thought to include a variety of pathologies including demyelination and/or fiber loss due to multifocal infarction and local ischemia. It is often accompanied by arteriosclerosis in deep penetrating arteries, multiple infarcts in the basal ganglia, brainstem or ce...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 5, 2024 Category: Research Source Type: funding
Notice of Special Interest (NOSI): Development of Imaging Techniques for High Resolution and Functional Scanning of In Vivo Human Sensory and Communication Systems
Notice NOT-DC-24-025 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2024 Category: Research Source Type: funding
Efficacy and Safety of Amyloid-Beta Directed Antibody Therapy in Mild Cognitive Impairment and Dementia with Evidence of Both Amyloid-Beta and Vascular Pathology (U01 - Clinical Trial Required)
Funding Opportunity RFA-NS-24-013 from the NIH Guide for Grants and Contracts. This RFA will solicit applications for a pivotal phase 3 clinical trial to determine the efficacy of FDA approved monoclonal antibody therapy compared to placebo in diverse "mixed dementia" populations with a focus on vascular contributions. Mixed dementia refers to dementia cases positive for 1) Alzheimer biomarkers, such as amyloid positron emission tomography and/or low cerebrospinal fluid amyloid beta 42 combined with elevated phosphorylated tau; and 2) evidence of vascular contributions based on imaging (white matter disease and/or subcl...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 19, 2023 Category: Research Source Type: funding
Equity Community Organizing (ECO) Groups to Advance Health Equity in Aging in California
Funding to organize community groups designed to reduce health inequities for older adults in California. The focus is on communities of color and communities where race and ethnicity intersect with
other factors such as age, gender, disability, sexual orientation, gender identity, socioeconomic status, geography, language, and/or immigration status leading to inequities. Geographic coverage: California -- California Health Care Foundation, The SCAN Foundation (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - September 25, 2023 Category: American Health Source Type: funding
HEAL Initiative: Developing an Evidence Base for Co-Occurring OUD-AUD Interventions (R34 Clinical Trial Optional)
Funding Opportunity RFA-AA-23-006 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) seeks to support studies that will inform safe and effective medication-assisted, psychosocial, and complementary interventions for people with co-occurring Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD). Alcohol increases lethal opioid overdose risk. As a result, treatment providers may under-prescribe or be reluctant to provide opioid agonist therapies (OATs) such as methadone and buprenorphine to people with OUD who also have AUD or misuse alcohol. There is also scant research on non-phar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 11, 2023 Category: Research Source Type: funding
HEAL Initiative: Developing an Evidence Base for Co-Occurring OUD-AUD Interventions (R01 Clinical Trial Optional)
Funding Opportunity RFA-AA-23-005 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) seeks to support studies that will inform safe and effective medication-assisted, psychosocial, and complementary interventions for people with co-occurring Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD). Alcohol increases lethal opioid overdose risk. As a result, treatment providers may under-prescribe or be reluctant to provide opioid agonist therapies (OATs) such as methadone and buprenorphine to people with OUD who also have AUD or misuse alcohol. There is also scant research on non-phar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 11, 2023 Category: Research Source Type: funding
Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)
Funding Opportunity PAR-23-164 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain and the incorporation of, pilot or clinical feasibility evaluation from previously collected data in pre-clinical studies. These studies are expected to provide the requisite data needed to advance promising PET ligands for use in clinical research. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 7, 2023 Category: Research Source Type: funding
Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-165 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research grant applications that propose the preclinical development of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in rodent and nonhuman primate brain and incorporation of pilot or clinical feasibility evaluation in pre-clinical studies and appropriate model development. Projects proposing clinical assessments of novel radioligands should respond to FOA PAR XX-XXX . (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 7, 2023 Category: Research Source Type: funding
Notice of Special Interest: Temporal Bone Histological Tissue Scanning Equipment Supplement
Notice NOT-DC-22-009 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 21, 2022 Category: Research Source Type: funding
Notice of Special Interest: Temporal Bone Histological Tissue Scanning Equipment Supplement
Notice NOT-DC-21-004 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 11, 2021 Category: Research Source Type: funding
Centers on Telehealth Research for Cancer-Related Care (P50 Clinical Trial Required)
Funding Opportunity RFA-CA-21-029 from the NIH Guide for Grants and Contracts. Informed by stakeholder input and a scan of the existing clinical and research landscape, the purpose of this initiative is to fund three research centers that can advance a national cancer-related telehealth research agenda in a rapidly changing healthcare, policy, and communication environment. Each center will support one signature project: a large pragmatic trial with the potential to generate findings with broad applicability to clinical practice and heterogenous patient populations. This collective of research centers will also support ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 8, 2021 Category: Research Source Type: funding
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Funding Opportunity PAR-21-208 from the NIH Guide for Grants and Contracts. The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is underrepresented or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction resea...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 26, 2021 Category: Research Source Type: funding
Welcome the New RePORT and RePORTER Tools!
Ten years ago, NIH launched the RePORT (Research Portfolio Online Reporting Tools) website to serve as a one-stop shop for reports, data, and analyses of NIH research activities. Well, drum roll please, a new and modernized RePORT site as well as a faster and easier to use NIH RePORTER have now arrived.
The updated RePORT site strives to meet the needs of today’s users based on feedback received over the years. It is easier, simpler, and quicker to access the same information you have come to rely upon. Right from the homepage, for instance, you can jump into data with interactive charts that connect out to NIH Data Bo...
Source: NIH Extramural Nexus - October 13, 2020 Category: Research Authors: Mike Lauer Tags: blog Open Mike ExPORTER Funding data NIH Data Book RePORT RePORTER Source Type: funding
New “All About Grants” Podcast on Notices of Special Interest (NOSIs)
Jodi Black, Ph.D., Deputy Director of NIH’s Office of Extramural Research
When dutifully scanning the weekly Table of Contents email for the NIH Guide for Grants and Contracts every Friday afternoon, have you found yourself wondering where all the Notices of Special Interest (NOSI) came from? And, what is a NOSI anyways?
Dr. Jodi Black, Deputy Director of NIH’s Office of Extramural Research, joins us in this next installment of the NIH’s All About Grants podcast series to break down NOSIs (MP3 / Transcript). We discuss what they are and why NIH is using them, what you should know about them when putting to...
Source: NIH Extramural Nexus - February 3, 2020 Category: Research Authors: NIH Staff Tags: New Resources All About Grants NOSI notices of special interest podcast Source Type: funding
Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)
Funding Opportunity PAR-20-038 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain and the incorporation of, pilot or clinical feasibility evaluation from previously collected data in pre-clinical studies. These studies are expected to provide the requisite data needed to advance promising PET ligands for use in clinical research. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 7, 2020 Category: Research Source Type: funding
