Current Concepts in Iodinated Contrast Induced Acute Kidney Injury
Iodinated contrast agents administered during computed tomography (CT) studies have the potential to cause post-contrast acute kidney injury (AKI). Prior to CT scans, in certain populations, assessment of the estimated glomerular filtration rate (eGFR) is required to identify patients at risk for adverse events after contrast administration. (Source: Journal of Radiology Nursing)
Source: Journal of Radiology Nursing - May 25, 2018 Category: Radiology Authors: Starr Urbano Tags: ARIN Poster Abstracts Source Type: research

Stryker Orthopaedic Modeling and Analytics (SOMA): A Review.
Authors: Schmidt W, LiArno S, Khlopas A, Petersik A, Mont MA Abstract Due to the differences in bone morphology between demographics such as age, gender, body mass index, and ethnicity, the development of orthopaedic implants requires a large number of anatomical data from various patient populations. In an effort to assess these demographic variations, Stryker Orthopaedic Modeling and Analytics (SOMA) has been developed. SOMA is a suite of tools which utilizes a comprehensive database of computed tomography scans (CT-scans), plus associated three-dimensional (3D) bone models, allowing the user to assess population...
Source: Surgical Technology International - May 25, 2018 Category: Surgery Tags: Surg Technol Int Source Type: research

Searching for Replicable Dopamine-Related Findings in Gambling Disorder
van Holst et  al. (1) used [18F]flouro-levo-diphenylalanine ([18F]DOPA) positron emission tomography (PET) to study individuals with and without pathological gambling (PG). They report that the PG group, as compared with the healthy control (HC) group, demonstrated higher dopamine synthesis capacity in three st riatal regions (the caudate body, dorsal putamen, and ventral striatum) and that dopamine synthesis capacity in two striatal regions (the caudate head and dorsal putamen) correlated with gambling-related distortions in the PG group. (Source: Biological Psychiatry)
Source: Biological Psychiatry - May 25, 2018 Category: Psychiatry Authors: Marc N. Potenza Tags: Commentary Source Type: research

Resolution of late-onset heart and liver failures after reversion of jejuno-ileal bypass: a case report.
CONCLUSIONS: This case demonstrate that in case of long-term and life-threatening complications, it is possible to successfully reverse JIB surgery after upto 30 years. The hypothesis on pathophysiology of heart and liver insufficiency are discussed. PMID: 29790800 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - May 25, 2018 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Mir-483 inhibits colon cancer cell proliferation and migration by targeting TRAF1
Publication date: Available online 24 May 2018 Source:The Kaohsiung Journal of Medical Sciences Author(s): Zi-Yu Niu, Wen-Li Li, Da-Lei Jiang, Yan-Song Li, Xiang-Jun Xie MicroRNAs are important regulators during human growth and development. Emerging evidence indicates that microRNAs play important roles in colorectal cancer. The aim of this study is to reveal the biological function and direct target gene of miR-483 in colorectal cancer. The biological function of miR-483 on the proliferation and migration of colon cancer cells was then examined by Edu assay and transwell assay, respectively. Our findings revealed that m...
Source: The Kaohsiung Journal of Medical Sciences - May 25, 2018 Category: Universities & Medical Training Source Type: research

Handgrip and knee extension strength as predictors of cancer mortality: A systematic review and meta ‐analysis
Scandinavian Journal of Medicine&Science in Sports, EarlyView. (Source: Scandinavian Journal of Medicine and Science in Sports)
Source: Scandinavian Journal of Medicine and Science in Sports - May 25, 2018 Category: Sports Medicine Authors: A. Garc ía‐Hermoso , R. Ramírez‐Vélez , M. D. Peterson , F. Lobelo , I. Cavero‐Redondo , J. E. Correa‐Bautista , V. Martínez‐Vizcaíno Source Type: research

Rapidly increasing off ‐label use of rituximab in multiple sclerosis in Sweden — Outlier or predecessor?
Acta Neurologica Scandinavica, EarlyView. (Source: Acta Neurologica Scandinavica)
Source: Acta Neurologica Scandinavica - May 25, 2018 Category: Neurology Authors: S. G. Berntsson , A. Kristoffersson , I. Bostr öm , A. Feresiadou , J. Burman , A. M. Landtblom Source Type: research

Risk factors for cardiopulmonary resuscitation ‐related injuries sustained during out‐of‐hospital cardiac arrests
Acta Anaesthesiologica Scandinavica, EarlyView. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - May 25, 2018 Category: Anesthesiology Authors: P. Set älä , H. Hellevuo , H. Huhtala , A. Kämäräinen , J. Tirkkonen , S. Hoppu Source Type: research

Use of β-cyclodextrin as enhancer of ascorbic acid rejection in permselective films for amperometric biosensor applications.
Use of β-cyclodextrin as enhancer of ascorbic acid rejection in permselective films for amperometric biosensor applications. Talanta. 2018 Aug 15;186:53-59 Authors: Monti P, Rocchitta G, Marceddu S, Dettori MA, Fabbri D, Jaoua S, Migheli Q, Delogu G, Serra PA Abstract Interference rejection in amperometric biosensors can be more effective introducing some modifiers during electro-deposition of permselective film. Addition of β-cyclodextrin (βCD), a cyclic oligosaccharide composed of seven glucose units, to the ortho-phenylendiamine (oPD) monomer were already demonstrated to provide an e...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Monti P, Rocchitta G, Marceddu S, Dettori MA, Fabbri D, Jaoua S, Migheli Q, Delogu G, Serra PA Tags: Talanta Source Type: research

Nuclear proliferomics: A new field of study to identify signatures of nuclear materials as demonstrated on alpha-UO3.
Abstract The use of a limited set of signatures in nuclear forensics and nuclear safeguards may reduce the discriminating power for identifying unknown nuclear materials, or for verifying processing at existing facilities. Nuclear proliferomics is a proposed new field of study that advocates for the acquisition of large databases of nuclear material properties from a variety of analytical techniques. As demonstrated on a common uranium trioxide polymorph, α-UO3, in this paper, nuclear proliferomics increases the ability to improve confidence in identifying the processing history of nuclear materials. Specifi...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Schwerdt IJ, Brenkmann A, Martinson S, Albrecht BD, Heffernan S, Klosterman MR, Kirkham T, Tasdizen T, McDonald Iv LW Tags: Talanta Source Type: research

A sensitively non-enzymatic amperometric sensor and its application in living cell superoxide anion radical detection.
Abstract Here, we report a nanocomposite composed of silver nanoparticles and multi-walled carbon nanotubes (AgNPs/MWNTs) utilized as an efficient electrode material for sensitive detection superoxide anion (O2•-). The procedure to synthesize AgNPs/MWNTs nanocomposites was green and facile. In the presence of functionalized multi-wall carbon nanotubes (MWNTs), silver nanoparticles (AgNPs) were in situ generated by chemical reduction of silver nitrate with glucose as a reducing and stabilizing agent to give the desired AgNPs/MWNTs nanocomposites. The nanocomposites can be easily used for the construction of an...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Liu X, Ran M, Liu G, Liu X, Xue Z, Lu X Tags: Talanta Source Type: research

Highly selective and sensitive chemiluminescence biosensor for adenosine detection based on carbon quantum dots catalyzing luminescence released from aptamers functionalized graphene@magnetic β-cyclodextrin polymers.
Highly selective and sensitive chemiluminescence biosensor for adenosine detection based on carbon quantum dots catalyzing luminescence released from aptamers functionalized graphene@magnetic β-cyclodextrin polymers. Talanta. 2018 Aug 15;186:238-247 Authors: Sun Y, Ding C, Lin Y, Sun W, Liu H, Zhu X, Dai Y, Luo C Abstract In this work, a highly selective and sensitive chemiluminescence (CL) biosensor was prepared for adenosine (AD) detection based on carbon quantum dots (CQDs) catalyzing the CL system of luminol-H2O2 under alkaline environment and CQDs was released from the surface of AD aptamers...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Sun Y, Ding C, Lin Y, Sun W, Liu H, Zhu X, Dai Y, Luo C Tags: Talanta Source Type: research

Graphene oxide-based composite monolith as new sorbent for the on-line solid phase extraction and high performance liquid chromatography determination of ß-sitosterol in food samples.
Graphene oxide-based composite monolith as new sorbent for the on-line solid phase extraction and high performance liquid chromatography determination of ß-sitosterol in food samples. Talanta. 2018 Aug 15;186:200-205 Authors: Cui B, Guo B, Wang H, Zhang D, Liu H, Bai L, Yan H, Han D Abstract A composite monolithic column was prepared by redox initiation method for the on-line purification and enrichment of β-sitosterol, in which graphene oxide (GO) was embedded. The obtained monolithic column was characterized by scanning electron microscopy (SEM) and nitrogen adsorption-desorption isotherm...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Cui B, Guo B, Wang H, Zhang D, Liu H, Bai L, Yan H, Han D Tags: Talanta Source Type: research

Electronic eye for the prediction of parameters related to grape ripening.
Abstract An electronic eye (EE) for fast and easy evaluation of grape phenolic ripening has been developed. For this purpose, berries of different grape varieties were collected at different harvest times from veraison to maturity, then an amount of the derived must was deposited on a white sheet of absorbent paper to obtain a sort of paper chromatography. Thus, RGB images of the must spots were collected using a flatbed scanner and converted into one-dimensional signals, named colourgrams, which codify the colour properties of the images. The dataset of colourgrams was used to build calibration models to relate t...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Orlandi G, Calvini R, Pigani L, Foca G, Vasile Simone G, Antonelli A, Ulrici A Tags: Talanta Source Type: research

Development of dried serum spot sampling techniques for the assessment of trace elements in serum samples by LA-ICP-MS.
Moreda-Piñeiro A Abstract A novel approach for serum analysis by dried matrix spot (DMS) technique is proposed. The methodology consists of sampling filter paper discs (2.7 mm in diameter) containing the large amount of serum retained after a single spotting. Several oxidizers (sodium chlorate, sodium azide, acetic acid, formic acid, 1-butyl-3-methylimidazoliumm chloride/bromide) were tested (oxidizers premixed with the sample before spotting, and papers previously soaked in concentrated additive/oxidizer solutions). Direct multi-element determination (Al, Be, Ca, Cu, Fe, K, Li, Mg, Mn, Mo, Na, P, Rb, Se,...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Chantada-Vázquez MP, Moreda-Piñeiro J, Cantarero-Roldán A, Bermejo-Barrera P, Moreda-Piñeiro A Tags: Talanta Source Type: research

Transmission infrared imaging microscopy and multivariate curve resolution applied to the forensic examination of automotive paints.
Abstract In the forensic examination of automotive paint, each layer of paint is analyzed individually by infrared (IR) spectroscopy. Laboratories in North America typically hand section each layer and present each separated layer to the spectrometer for analysis, which is time consuming. In addition, sampling too close to the boundary between adjacent layers can pose a problem as it produces an IR spectrum that is a mixture of the two layers. Not having a "pure" spectrum of each layer will prevent a meaningful comparison between each paint layer or in the situation of searching an automotive database wi...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Kwofie F, Perera UDN, Allen MD, Lavine BK Tags: Talanta Source Type: research

Source attribution profiling of five species of Amanita mushrooms from four European countries by high resolution liquid chromatography-mass spectrometry combined with multivariate statistical analysis and DNA-barcoding.
ot C Abstract Source attribution profiling of five species of Amanita mushrooms from four European countries was performed using Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) combined with multivariate statistical analysis. Initially, species determination was carried out morphologically and was verified by DNA-analysis. This data was then combined with chemical profiling, generated from LC-HRMS full scan analysis. The untargeted data was processed and the 720 most abundant peaks in the LC-HRMS chromatogram were used to build a multivariate PLS-DA model. The two independent methods for species ...
Source: Talanta - May 24, 2018 Category: Chemistry Authors: Jansson D, Wolterink A, Bergwerff L, Hough P, Geukens K, Åstot C Tags: Talanta Source Type: research

Synthesis of Chelating Agent Free-Solid Phase Extractor (CAF-SPE) Based on New SiO2/Al2O3/SnO2 Ternary Oxide and Application for Online Preconcentration of Pb2+ Coupled with FAAS
A new online solid phase preconcentration method using the new SiO2/Al2O3/SnO2 ternary oxide (designated as SiAlSn) as chelating agent free-solid phase extractor (CAF-SPE) coupled to flame atomic absorption spectrometry (FAAS) for Pb2+ determination at trace levels in different kind of samples is proposed. The solid adsorbent has been characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron miscroscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray fluorescence spectroscopy (XRF) and textural data. The method involves the preconcentration using time-based sampling of Pb2+ solution at pH ...
Source: Journal of the Brazilian Chemical Society - May 24, 2018 Category: Chemistry Source Type: research

Ultra-structural evaluation of needles and their role for comfort during subcutaneous drug administration
Conclusions The standardization of fixed needle syringes, or the use of a single needle for both the preparation and the subcutaneous drug administration should be considered as strategies to reduce the production of sharp-perforating residues, to decrease the cost per procedure, and to limit the risk of contamination of critical devices. (Source: Revista da Escola de Enfermagem da USP)
Source: Revista da Escola de Enfermagem da USP - May 24, 2018 Category: Nursing Source Type: research

Chlorhexidine and proanthocyanidin enhance the long-term bond strength of resin-based endodontic sealer
Abstract The aim of this study was to evaluate the effects of proanthocyanidin (PA) and chlorhexidine (CHX) on the bond strength (BS), failure pattern, and resin-dentin interface morphology of the endodontic sealers EndoREZ and AH Plus after 24 h and 6 months of water storage. A total of 120 prepared bovine roots were divided into six groups: AH Plus, CHX+AH Plus, PA+AH Plus, EndoREZ, CHX+EndoREZ, and PA+EndoREZ. Dentin was treated for 1 or 5 min with 2% CHX or 15% PA, respectively. Roots were filled and stored in water for 24 h or 6 months (n = 10). Root slices were subjected to push-out test and scanning electron microsc...
Source: Brazilian Oral Research - May 24, 2018 Category: Dentistry Source Type: research

The effect of hydrofluoric acid and resin cement formulation on the bond strength to lithium disilicate ceramic
Abstract To investigate how the hydrofluoric acid (HF) concentrations applied to a lithium disilicate glass-ceramic (EMX) affects the surface morphology and microtensile bond strength ( μ TBS) of ceramics to dentin, using light-cured resin cements with or without UDMA. Sixty-three EMX square ceramic blocks were etched for 20 seconds using different HF concentrations (1%, 5% and 10%) and luted to dentin using two types of resin cement combinations: BisGMA/TEGDMA and BisGMA/TEGDMA/UDMA (n = 10). Each bonded EMX-dentin block was sectioned to obtain 1 mm2 sticks for μ TBS evaluation. Half of the sticks were tested after ...
Source: Brazilian Oral Research - May 24, 2018 Category: Dentistry Source Type: research

The Functional Anatomy of the Superficial Fat Compartments of the Face: A Detailed Imaging Study
Conclusion: This study confirms the presence of distinct subcutaneous fat compartments and provides evidence for an individual behavior when soft-tissue fillers are applied: inferior displacement of the superficial nasolabial, middle cheek, and jowl compartments, in contrast to an increase in volume without displacement (i.e., an increase in projection) of the medial cheek, lateral cheek, and both superficial temporal compartments. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - May 24, 2018 Category: Cosmetic Surgery Tags: Cosmetic: Original Articles Source Type: research

Using Black Bone Magnetic Resonance Imaging in Craniofacial Virtual Surgical Planning: A Comparative Cadaver Study
Conclusions: This study demonstrates that virtual surgical planning and three-dimensional craniofacial surgical guide creation can be performed using black bone MRI with accuracy comparable to that of CT. This could dramatically reduce radiation exposure of craniofacial reconstruction patients. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - May 24, 2018 Category: Cosmetic Surgery Tags: Pediatric/Craniofacial: Original Article Source Type: research

Osteoporosis Is Associated with Deteriorating Clinical Status in Adults with Cystic Fibrosis.
Conclusions: Osteoporosis in CF occurs with deteriorating clinical status while the role of calcium metabolism seems minor. Gender specific and dysglycemic impact on bone status should be investigated further. PMID: 29780417 [PubMed] (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - May 24, 2018 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Functionalized Caprolactone-Polyethylene Glycol Based Thermo-Responsive Hydrogels of Silibinin for the Treatment of Malignant Melanoma.
CONCLUSION: Our results imply a great potential for PolyGel TM formulations of silibinin for local treatment of malignant melanoma. This article is open to POST-PUBLICATION REVIEW. Registered readers (see "For Readers") may comment by clicking on ABSTRACT on the issue's content page. PMID: 29789104 [PubMed - in process] (Source: Journal of Pharmacy and Pharmaceutical Sciences)
Source: Journal of Pharmacy and Pharmaceutical Sciences - May 24, 2018 Category: Drugs & Pharmacology Tags: J Pharm Pharm Sci Source Type: research

The Value of 18F-FDG PET/CT Mathematical Prediction Model in Diagnosis of Solitary Pulmonary Nodules.
Conclusion: The mathematical predictive model has high accuracy in estimating the malignant probability of patients with SPNs. PMID: 29789808 [PubMed - in process] (Source: Biomed Res)
Source: Biomed Res - May 24, 2018 Category: Research Authors: Wang L, Chen Y, Tang K, Lin J, Zhang H Tags: Biomed Res Int Source Type: research

Biodegradable Alginate-Chitosan Hollow Nanospheres for Codelivery of Doxorubicin and Paclitaxel for the Effect of Human Lung Cancer A549 Cells.
Abstract A biodegradable alginate coated chitosan hollow nanosphere (ACHN) was prepared by a hard template method and used for codelivery of doxorubicin (DOX) and paclitaxel (PTX) to investigate the effect on human lung cancer A549 cells. PTX was loaded into the nanometer hollow structure of ACHN through adsorption method. DOX was coated on surface of ACHN through electrostatic interaction. Drug release studies exhibited a sustained-release effect. According to X-ray diffraction patterns (XRD), differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FT-IR) analysis, DOX structure in t...
Source: Biomed Res - May 24, 2018 Category: Research Authors: Tao L, Jiang J, Gao Y, Wu C, Liu Y Tags: Biomed Res Int Source Type: research

Visible- ‎enhanced ‎Photocatalytic ‎Performance of ‎CuWO4/WO3‎ Hetero-‎structure: ‎Incorporation of ‎Plasmonic Ag ‎Nanostructures
New J. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8NJ01656A, PaperReza Salimi, Ali Asghar Sabbagh Alvani, Naimeh Naseri, Shangfeng Du, Poelman Dirk A new plasmonic Ag hybridized CuWO4/WO3 heterostructure was successfully synthesized via ligand-assisted sol gel method. The as-prepared plasmonic nanohybrid was thoroughly characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM),... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - May 24, 2018 Category: Chemistry Authors: Reza Salimi Source Type: research

[ «Man-in-the-barrel» syndrome: atypical manifestation of giant cell arteritis].
CONCLUSIONS: Although the typical clinical manifestations of giant cell arteritis are headache, jaw claudication, loss of sight, constitutional symptoms and polymyalgia rheumatica, its presence must be suspected in patients over the age of 50 who manifest alterations affecting the peripheral nerve, including brachial diplegia with no other demonstrable cause. PMID: 29790570 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Calle-Lopez Y, Fernandez-Ramirez AF, Franco-Dager E, Gomez-Lopera JG, Vanegas-Garcia AL Tags: Rev Neurol Source Type: research

Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit
Manuel Men éndez-González, Tania Álvarez-Avellón, José M. Salas-Pacheco, Benito de Celis-Alonso, Kathryn A. Wyman-Chick, Oscar Arias-Carrión (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - May 24, 2018 Category: Neurology Source Type: research

Reduction of Vascular Inflammation, LDL-C, or Both for the Protection from Cardiovascular Events?
Conclusion: Both LDL-C and inflammation reduction are beneficial to the reduction of CVD risk. However, canakinumab is a very expensive drug that only induced a 15% reduction in CVD events, thus drastically reducing the possibility for it to be used in clinical practice. Besides, canakinumab is associated with increased infections, some fatal. A potent statin with anti-inflammatory effects is probably the best choice for the majority of those needing hypolipidaemic drug therapy. PMID: 29785212 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - May 24, 2018 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research

Relationship of Radiometabolic Biomarkers to KRAS Mutation Status and ALK Rearrangements in Cases of Lung Adenocarcinoma.
Conclusions The small numbers of KRAS mutations and ALK rearrangements are the limitation of this study for evaluation of diagnostic imaging. The frequency of these genetic alterations was as reported in the literature. We believe that our work will contribute to future meta-analysis. PMID: 29781772 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 24, 2018 Category: Cancer & Oncology Tags: Tumori Source Type: research

Scanning two-photon continuous flow lithography for synthesis of high-resolution 3D microparticles: erratum
An error in a reference is reported and corrected. (Source: Optics Express)
Source: Optics Express - May 24, 2018 Category: Physics Authors: Lucas A. Shaw Samira Chizari Maxim Shusteff Hamed Naghsh-Nilchi Dino Di Carlo Jonathan B. Hopkins Source Type: research

Application of 25  MHz B-Scan Ultrasonography to Determine the Integrity of the Posterior Capsule in Posterior Polar Cataract.
Conclusion: This is the first report to show that 25 MHzB can be used to clearly visualize the status of the PC in PPC. These results, in turn, could be used to select the appropriate treatment and to thereby avoid further complications during PPC surgery. PMID: 29785304 [PubMed] (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - May 24, 2018 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Evaluation of methods for volumetric analysis of pediatric brain data: The childmetrix pipeline versus adult-based approaches
Publication date: Available online 23 May 2018 Source:NeuroImage: Clinical Author(s): Thanh Vân Phan, Diana M. Sima, Caroline Beelen, Jolijn Vanderauwera, Dirk Smeets, Maaike Vandermosten Pediatric brain volumetric analysis based on Magnetic Resonance Imaging (MRI) is of particular interest in order to understand the typical brain development and to characterize neurodevelopmental disorders at an early age. However, it has been shown that the results can be biased due to head motion, inherent to pediatric data, and due to the use of methods based on adult brain data that are not able to accurately model the anatomic...
Source: NeuroImage: Clinical - May 24, 2018 Category: Radiology Source Type: research

Parkinson's disease related signal change in the nigrosomes 1 –5 and the substantia nigra using T2* weighted 7T MRI
In this study we aimed to determine whether MRI can detect the smaller nigrosomes (N2–N5) and whether graded signal alterations can be detected on T2*-weighted MRI at different disease stages consistent with histopathological changes. An observational prospective study was performed within the research imaging centre at the University of Nottingham, UK. Altogether 26 individuals with confirmed PD (median Hoehn&Yahr stage = 1, Unified PD Rating Scale [UPDRS] = 12.5) and 15 healthy controls participated. High resolution T2*weighted 7 T MRI of the brain was performed and visibility of N1-N5 within the ...
Source: NeuroImage: Clinical - May 24, 2018 Category: Radiology Source Type: research

Development of a bedside applicable ultrasound protocol to estimate fat mass index derived from whole body dual-energy x-ray absorptiometry scans
Precise measures of adiposity are difficult to obtain in clinical settings due to a lack of access to accurate and reliable techniques. The aim of this study was to develop and internally validate a bedside applicable ultrasound protocol to estimate fat mass index. (Source: Nutrition)
Source: Nutrition - May 24, 2018 Category: Nutrition Authors: Michael T. Paris, Marina Mourtzakis Source Type: research

Learner-centred teaching in a non-learner-centred world: An interpretive phenomenological study of the lived experience of clinical nursing faculty
With the growing complexities in the contemporary health care system, there is a challenge of preparing nurses for the practice demands. To this end, learner-centred teaching has emerged in many nursing curricula in Canada and evidence indicates its effectiveness in developing the essential practice skills in nursing students. It is important to examine the experience of the clinical faculty members who implement learner-centred teaching, as doing so would provide an insight to the factors that may hinder the implementation of learner-centred teaching in the practice settings. (Source: Nurse Education Today)
Source: Nurse Education Today - May 24, 2018 Category: Nursing Authors: Olabisi Oyelana, Donna Martin, Judith Scanlan, Beverley Temple Source Type: research

Bilateral Caudate Nucleus Infarctions Following Upper Gastrointestinal Bleeding
A 75-year-old woman presented with consciousness disturbance accompanied by hematemesis. Brain imaging revealed ischemia in the bilateral caudate nuclei and right cerebral watershed area due to stenosis of the right anterior cerebral artery (ACA) and bilateral internal carotid arteries (ICA), and hypoperfusion in the right caudate nucleus. The patient's only symptom was abulia, which gradually resolved. Further brain scans showed that the ICA stenosis had improved, although the right ACA stenosis persisted. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Kensuke Daida, Nobukazu Miyamoto, Hiromi Takagi, Yuji Ueno, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Case Studies Source Type: research

Cost-effectiveness Analysis of Magnetic Resonance Imaging-Conditional Pacemaker Implantation: Insights from a Multicenter Study and Implications in the Current Era
MRI-conditional pacemakers (M-PPM) grant patients more accessibility to MRI scans. The cost-effectiveness of implanting M-PPM is unknown. (Source: Heart Rhythm)
Source: Heart Rhythm - May 24, 2018 Category: Cardiology Authors: Philip L. Mar, Guanhua Chen, Gaurang Gandhi, Zheng-Zheng Tang, Amy Leiserowitz, Ajay Tripuraneni, Eric Kreps, Luke Botting, Dhanunjaya Lakkireddy, Jerome E. Granato, Rakesh Gopinathannair Source Type: research

A Monte Carlo study of impact of scan position for cone beam CT on doses to organs and effective dose
Publication date: October 2018 Source:Radiation Physics and Chemistry, Volume 151 Author(s): Abdullah Abuhaimed, Colin J. Martin For multi-detector CT scans, the region of the body irradiated is determined from the scan projection radiograph and is adjusted for each patient. However, for cone beam CT scans, standard field sizes are often used without any adjustment for patient size. Moreover, when cone beam CT is used with image guided radiation therapy, the scan position varies with each patient, based on the tumour position and clinical requirements. The aim of this study is to quantify the influence of the position of ...
Source: Radiation Physics and Chemistry - May 24, 2018 Category: Physics Source Type: research

Psychosocial assessment and intervention – are we doing enough?
Much of the focus of preventive cardiology has been – and continues to be – on issues such as physical activity, weight reduction, dietary change, drug therapy. Whilst this is important and laudable comparatively scant attention has been focused on psychosocial aspects such as depression, anxiety and social isolation. Assessing and intervening to alleviate these issues impacts not only directly but indirectly on how well people can manage to increase physical activity, reduce weight and adhere to diets and medications. (Source: Heart and Lung)
Source: Heart and Lung - May 24, 2018 Category: Intensive Care Authors: David R. Thompson, Chantal F. Ski, Hugo Saner Source Type: research

Influence of alkoxy tail length on the properties of side chain liquid crystal polymers with aggregation –induced emission enhancement characteristics
Publication date: August 2018 Source:European Polymer Journal, Volume 105 Author(s): Yongjie Yuan, Jindi Li, Lifang He, Hailiang Zhang In this paper, a series of side chain liquid crystal polymers (SCLCPs) containing cyanostilbene cores, alkoxy tail namely poly[(Z)-6-(4-(1-cyano-2-(4-(alkoxy)phenyl)vinyl)phenoxy)hexyl methacrylate]s (abbreviated as PM6PVPCm, m is the alkoxy tail length) were synthesized and the effects of the alkoxy tail length on the properties of the SCLCPs were explored. The structures and properties of the SCLCPs were measured by 1H nuclear magnetic resonance (1HNMR), thermogravimetric analysis (TGA),...
Source: European Polymer Journal - May 24, 2018 Category: Chemistry Source Type: research

Molecules, Vol. 23, Pages 1256: A Gelatin Hydrogel-Containing Nano-Organic PEI –Ppy with a Photothermal Responsive Effect for Tissue Engineering Applications
In this study, a cationic photothermal triggerable/guidable gelatin hydrogel containing a polyethylenimine (PEI)–Ppy nanocomplex with a porous microstructure was established, and its physicochemical characteristics were studied through dynamic light scattering, scanning electronic microscopy, transmission electron microscopy, an FTIR; and cellular interaction behaviors towards fibroblasts incubated with a test sample were examined via MTT assay and fluorescence microscopy. Photothermal performance was evaluated. Furthermore, the in vivo study was performed on male Wistar rat full thickness excisions model for...
Source: Molecules - May 24, 2018 Category: Chemistry Authors: Mantosh Kumar Satapathy Batzaya Nyambat Chih-Wei Chiang Chih-Hwa Chen Pei-Chun Wong Po-Hsien Ho Pei-Ru Jheng Thierry Burnouf Ching-Li Tseng Er-Yuan Chuang Tags: Article Source Type: research

Risks and Recommendations in Prenatally Detected De Novo Balanced Chromosomal Rearrangements from Assessment of Long-Term Outcomes
The 6% –9% risk of an untoward outcome previously established by Warburton for prenatally detected de novo balanced chromosomal rearrangements (BCRs) does not account for long-term morbidity. We performed long-term follow-up (mean 17 years) of a registry-based nationwide cohort of 41 individuals carrying a prenatally detected de novo BCR with normal first trimester screening/ultrasound scan. We observed a significantly higher frequency of neurodevelopmental and/or neuropsychiatric disorders than in a matched control group (19.5% versus 8.3%, p = 0.04), which was increased to 26.8% upon clinical fol low-up. (Source: T...
Source: The American Journal of Human Genetics - May 24, 2018 Category: Genetics & Stem Cells Authors: Christina Halgren, Nete M. Nielsen, Lusine Nazaryan-Petersen, Asli Silahtaroglu, Ryan L. Collins, Chelsea Lowther, Susanne Kjaergaard, Morten Frisch, Maria Kirchhoff, Karen Br øndum-Nielsen, Allan Lind-Thomsen, Yuan Mang, Zahra El-Schich, Claire A. Borin Tags: Article Source Type: research

Diuretic renography in hydronephrosis: a retrospective single-center study
ConclusionsThe combination of ultrasound and MAG3 provides the necessary anatomical and functional information to follow the degree of obstruction and to decide between surgical intervention and conservative follow-up. Our study supports a threshold of 20  mm rather than 15 mm for severe obstruction and a low DRF. An APD threshold greater than 15 mm did not have a predictive value in DRF estimation. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - May 24, 2018 Category: Urology & Nephrology Source Type: research

A prospective observational trial of fusion imaging in infrarenal aneurysms
Use of three-dimensional fusion has been shown to significantly reduce radiation exposure and contrast material use in complex (fenestrated and branched) endovascular aneurysm repair (EVAR). Cydar software (CYDAR Medical, Cambridge, United Kingdom) is a cloud-based technology that can provide imaging guidance by overlaying preoperative three-dimensional vessel anatomy from computed tomography scans onto live fluoroscopy images both in hybrid operating rooms and on mobile C-arms. The aim of this study was to determine whether radiation dose reduction would occur with the addition of fusion imaging to infrarenal repair in al...
Source: Journal of Vascular Surgery - May 24, 2018 Category: Surgery Authors: Blandine Maurel, Teresa Martin-Gonzalez, Debra Chong, Andrew Irwin, Guillaume Guimbreti ère, Meryl Davis, Tara M. Mastracci Tags: Clinical paper Source Type: research

Sacituzumab Govitecan (IMMU-132) in treatment-resistant uterine serous carcinoma: A case report
Conclusion Sacituzumab govitecan may present a new treatment option for recurrent USC patients harboring Trop-2+ tumors resistant to chemotherapy. Clinical trials with sacituzumab govitecan are warranted. (Source: Gynecologic Oncology Reports)
Source: Gynecologic Oncology Reports - May 24, 2018 Category: OBGYN Source Type: research

Comparing population and incident data for optimal air ambulance base locations in Norway
Helicopter emergency medical services are important in many health care systems. Norway has a nationwide physician manned air ambulance service servicing a country with large geographical variations in populat... (Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine)
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - May 24, 2018 Category: Emergency Medicine Authors: Jo R øislien, Pieter L. van den Berg, Thomas Lindner, Erik Zakariassen, Oddvar Uleberg, Karen Aardal and J. Theresia van Essen Tags: Original research Source Type: research

Digital intraoral scanning technique for edentulous jaws
Publication date: May 2018 Source:The Journal of Prosthetic Dentistry, Volume 119, Issue 5 Author(s): Jing-Huan Fang, Xueyin An, Seung-Mi Jeong, Byung-Ho Choi Few studies have evaluated direct digital scans of edentulous jaws using intraoral scanners because it is difficult to scan edentulous sites that are smooth and devoid of features. A scanning technique is introduced for making direct digital scans of edentulous jaws with intraoral scanners in patients with a broad palate. (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 24, 2018 Category: Dentistry Source Type: research