Randomized clinical trial to evaluate safety and efficacy of convalescent plasma use among hospitalized patients with COVID-19 (PERUCONPLASMA): a structured summary of a study protocol for a randomized controlled trial
AbstractObjectivesThe general objective of this study is to test the hypothesis that administration of convalescent plasma from donors with previous diagnosis of severe COVID-19 pneumonia is safe and associated with a decrease in all-cause in-hospital mortality among hospitalized patients with COVID-19 at 30 days in comparison with standard treatment alone.The secondary objectives are as follows: (1) to assess the efficacy of convalescent plasma to reduce the length of hospitalization, (2) to assess the efficacy of convalescent plasma to reduce the length of ICU stay, and (3) to assess the efficacy of convalescent plasm...
Source: Trials - May 17, 2021 Category: Research Source Type: clinical trials
Randomized clinical trial to compare the efficacy of ivermectin versus placebo to negativize nasopharyngeal PCR in patients with early COVID-19 in Peru (SAINT-Peru): a structured summary of a study protocol for randomized controlled trial
AbstractObjectivesThe primary objective is to determine the effect of a daily dose of ivermectin administered in three consecutive days to non-severe COVID-19 patients with no more than 96 hours of symptoms, on the detection of SARS-CoV-2 RNA by PCR from nasopharyngeal swabs at day seven post-treatment initiation.The secondary objectives are:To assess the efficacy of ivermectin to reduce the SARS-CoV-2 viral load in the nasopharyngeal swab on days 4, 7, 14 and 21 post-treatment initiationTo assess the efficacy of ivermectin on the improvement of symptomsTo assess the proportion of seroconversions at day 21To assess the saf...
Source: Trials - April 9, 2021 Category: Research Source Type: clinical trials
Ensuring Quality in Psychological Support
Conditions: Psychological Distress; Depression Interventions: Behavioral: Ensuring Quality in Psychological Support; Behavioral: Standard Training and Supervision Sponsors: George Washington University; World Health Organization; The Center for Victims of Torture, United States; University of Washington; University of Nairobi; War Child Holland; Socios En Salud Sucursal, Peru; University of South Florida; HealthRight International; Johns Hopkins University; Centre for Infectious Disease Research in Zambia; The University of New South...
Source: ClinicalTrials.gov - January 11, 2021 Category: Research Source Type: clinical trials
