H.I.V. Cases Lead Indiana to Extend Needle Exchanges
Gov. Mike Pence has added another 30 days to the needle program in Scott County, where a health emergency was declared linking the virus to intravenous use of the painkiller Opana. (Source: NYT)
Source: NYT - April 21, 2015 Category: American Health Authors: ABBY GOODNOUGH Tags: Drug Abuse and Traffic Scott County (Ind) Hypodermic Needles and Syringes Medicine and Health Indiana Pence, Mike Source Type: news

H.I.V. Cases Lead Indiana to Extend Needle Exchanges
Gov. Mike Pence has added another 30 days to the needle program in Scott County, where a health emergency was declared linking the virus to intravenous use of the painkiller Opana. (Source: NYT Health)
Source: NYT Health - April 21, 2015 Category: Consumer Health News Authors: ABBY GOODNOUGH Tags: Drug Abuse and Traffic Scott County (Ind) Hypodermic Needles and Syringes Medicine and Health Indiana Pence, Mike Source Type: news

Indiana Races to Fight H.I.V. Surge Tied to Drug Abuse
The worst outbreak in Indiana’s history, which stems largely from the intravenous use of the prescription painkiller Opana, has prompted a whirlwind response effort. (Source: NYT Health)
Source: NYT Health - March 30, 2015 Category: Consumer Health News Authors: ABBY GOODNOUGH Tags: Pepsico Inc PEP NYSE Drug Abuse and Traffic Acquired Immune Deficiency Syndrome Hypodermic Needles and Syringes Medicine and Health Indiana Pence, Mike Source Type: news

Indiana Gov. Mike Pence Overrides State Law To Authorize Needle-Exchange Program
INDIANAPOLIS (AP) — Indiana Gov. Mike Pence overrode state law and his own anti-drug policies Thursday to authorize a short-term needle-exchange program designed to help contain HIV infections in a rural county where more than six dozen cases have been reported, all of them tied to intravenous drug use. Pence issued an executive order declaring a public health emergency in Scott County, an economically depressed area about 30 miles north of Louisville, Kentucky, that has seen 79 new infections since December. The county typically sees only about five HIV cases each year, health officials said. All of those infected eit...
Source: Science - The Huffington Post - March 26, 2015 Category: Science Source Type: news

Counties in California sue manufacturers of opioid analgesics
This week, two counties in California sues five manufacturers of opioid analgesics, accusing them of carrying out a “campaign of deception” to boost sales of their products. According to a report in the Los Angeles Times: In sweeping language reminiscent of the legal attack against the tobacco industry, the lawsuit alleges the drug companies have reaped blockbuster profits by manipulating doctors into believing the benefits of narcotic painkillers outweighed the risks, despite “a wealth of scientific evidence to the contrary.” The effort “opened the floodgates” for such drugs and “...
Source: The Poison Review - May 25, 2014 Category: Toxicology Authors: Leon Tags: Medical lawsuit opiates opioid analgesics pain as fifth vital sign Source Type: news

Quantification Of Oxycodone And Its Major Metabolites In Human Plasma By HPLC/MS/MS
BASi has developed a sensitive, specific and robust method for detecting and quantifying oxycodone and its two majormetabolites, noroxycodone and oxymorphone, in human plasma.By Mary E. Leonard, Vance Cooper, and Lori Payne (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - August 23, 2013 Category: Pharmaceuticals Source Type: news

Oxymorphone, incredible mosquito videos, and more: Weekly Web Review in Toxicology
http://www.youtube.com/watch?v=RLIYuXlUS3k It ain’t tox, but . . .: The must-see video’s of the week were included in a fascinating post by Ed Yong on the National Geographic site. They illustrate what happens on a microscopic level as a mosquito stings and searches for blood vessels. The clip above shows the surprisingly complex proboscis probing for its next meal. In the clip below, it strikes pay dirt. One wonders if the mosquito would have more success using ultrasound: http://www.youtube.com/watch?v=MbXSPacvuak ER visits and prescription stimulants: The Drug Abuse Warning Network (DAWN) reported this wee...
Source: The Poison Review - August 10, 2013 Category: Toxicology Authors: Leon Tags: Medical adderall mosquito nebulized naloxone opana oxymorphone Ritalin Source Type: news

Case report: hearing loss after snorting oxymorphone
2.5 out of 5 stars Oxymorphone Insufflation Associated with Acute Sensorineural Hearing Loss: Case Files of the University of Massachusetts Medical Toxicology Fellowship. Boyle KL, Rosenbaum CD. J Med Toxicol 2013 Jun:9:179-183. No abstract available This case report describes a 37-year-old man who experienced transient partial hearing loss after snorting crushed Opana® (oxymorphone). The case itself isn’t much, but it provides the opportunity for the authors to present a good discussion of drug-induced ototoxicity. Although opiate-associated hearing loss (OAHL) is well described, the authors state that this is th...
Source: The Poison Review - June 18, 2013 Category: Toxicology Authors: Leon Tags: Medical narcotics opana opiates ototoxicity sensorineural hearing loss Source Type: news

FDA Decision Opens Way to Generics of Original Opana ER FDA Decision Opens Way to Generics of Original Opana ER
Following a decision to block new generic versions of non-abuse-deterrent oxycodone, the FDA today denied a petition from Endo Pharmaceuticals, opening the way for new generic versions of oxymorphone. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 11, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

FDA Allows Generic Form of Painkiller
The FDA ruled that a new version of the powerful painkiller Opana ER doesn't thwart drug abuse significantly better than earlier versions that aren't abuse-deterrent. (Source: WSJ.com: Health)
Source: WSJ.com: Health - May 11, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news

Endo Loses Bid to Block Sales of Generic Painkiller
The agency’s decision on generic Opana ER came just weeks after it reached the opposite conclusion in the case of another frequently abused painkiller, OxyContin.     (Source: NYT Health)
Source: NYT Health - May 11, 2013 Category: Consumer Health News Authors: By KATIE THOMAS Tags: Pain-Relieving Drugs Drugs (Pharmaceuticals) Opana ER Food and Drug Administration Endo Health Solutions OxyContin (Drug) Generic Brands and Products Source Type: news

FDA allows generic forms of Endo Health's Opana ER painkiller
(Reuters) - The U.S. Food and Drug Administration on Friday denied Endo Health Solutions' petition to block generic forms of its widely abused prescription pain drug Opana ER, a surprise decision by an agency that has recently come down hard on pain drugs to prevent their abuse. (Source: Reuters: Health)
Source: Reuters: Health - May 10, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Rejects Endo Petition To Protect Its Opana Painkiller
In a rebuff to Endo Health Solutions, the FDA has denied a citizen petition that the drugmaker had filed last year in an attempt to thwart generic competition to its Opana ER painkiller. The decision is a setback for the drugmaker because not only does it mean that generics will soon become available, but the FDA denial is also likely to diminish the value of its newer, reformulated Opana ER. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 10, 2013 Category: Pharmaceuticals Authors: Ed Silverman Source Type: news

FDA Allows Opana Generics
(MedPage Today) -- The original formulation of extended-release oxymorphone (Opana ER) that lacked abuse-resistant mechanisms was not pulled from the market for safety reasons, and therefore generics based on that recipe are permissible, the FDA said. (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - May 10, 2013 Category: Neurology Source Type: news

TTP-Like Illness Associated With Intravenous Opana ER AbuseTTP-Like Illness Associated With Intravenous Opana ER Abuse
What types of illnesses can potentially present after intravenous administration of extended-release forms of oxymorphone? This new report takes a look at incidences of TTP-like illness. Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 28, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news