Antifungal Selection for the Treatment of Onychomycosis: Patient Considerations and Outcomes
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - March 4, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Safety assessment for nail cosmetics: Framework for the estimation of systemic exposure through the nail plate
Regul Toxicol Pharmacol. 2024 Feb 27:105588. doi: 10.1016/j.yrtph.2024.105588. Online ahead of print.ABSTRACTAll cosmetics products, including nail care products, must be evaluated for their safety. The assessment of systemic exposure is a key component of the safety assessment. However, data on the exposure, especially via ungual route (nail plate) are limited. Based on the physicochemical properties of human nails and permeability data of topical onychomycosis drugs, the nail plate is considered a good barrier to chemicals. We examine factors impacting penetration of nail care ingredients through the nail plate, includin...
Source: Regulatory Toxicology and Pharmacology : RTP - February 29, 2024 Category: Toxicology Authors: Xuejun J Yin Nicola J Hewitt Steffen Erler Paul Bryson Brunhilde Bl ömeke Anthony A Gaspari Carsten Goebel Source Type: research
Safety assessment for nail cosmetics: Framework for the estimation of systemic exposure through the nail plate
Regul Toxicol Pharmacol. 2024 Feb 27:105588. doi: 10.1016/j.yrtph.2024.105588. Online ahead of print.ABSTRACTAll cosmetics products, including nail care products, must be evaluated for their safety. The assessment of systemic exposure is a key component of the safety assessment. However, data on the exposure, especially via ungual route (nail plate) are limited. Based on the physicochemical properties of human nails and permeability data of topical onychomycosis drugs, the nail plate is considered a good barrier to chemicals. We examine factors impacting penetration of nail care ingredients through the nail plate, includin...
Source: Regulatory Toxicology and Pharmacology : RTP - February 29, 2024 Category: Toxicology Authors: Xuejun J Yin Nicola J Hewitt Steffen Erler Paul Bryson Brunhilde Bl ömeke Anthony A Gaspari Carsten Goebel Source Type: research
