Association between onychomycosis and ulcerative complications in patients with diabetes: a longitudinal cohort study in Dutch general practice
Conclusions
Onychomycosis significantly increased the risk of ulcer development in patients with DM in primary care, independently of other risk factors. In addition, onychomycosis increased the risk of surgeries and infectious complications. These results underscore the importance of giving sufficient attention to onychomycosis in primary care and corresponding guidelines. Early identification of onychomycosis during screening and routine care provides a good opportunity for timely recognition of increased ulcer risk. (Source: BMJ Open)
Source: BMJ Open - April 23, 2024 Category: General Medicine Authors: Watjer, R. M., Heckmans, K. M., Eekhof, J. A., Gummi, L., Quint, K. D., Numans, M. E., Bonten, T. N. Tags: Open access, Diabetes and Endocrinology Source Type: research
An update on antifungal resistance in Dermatophytosis
Expert Opin Pharmacother. 2024 Apr 16. doi: 10.1080/14656566.2024.2343079. Online ahead of print.ABSTRACTINTRODUCTION: The reports of resistance to antifungal agents used for treating onychomycosis and other superficial fungal infections are increasing. This rise in antifungal resistance poses a public health challenge that requires attention.AREAS COVERED: This review explores the prevalence of dermatophytes and the current relationship between dermatophyte species, their minimum inhibitory concentrations (MICs) for terbinafine (an allylamine) and itraconazole (an azole), and various mutations prevalent in these species. ...
Source: Expert Opinion on Pharmacotherapy - April 16, 2024 Category: Drugs & Pharmacology Authors: Aditya K Gupta Avantika Mann Shruthi Polla Ravi Tong Wang Source Type: research
Onychomycosis
This Patient Page describes the risk factors, clinical features, diagnosis, and treatment of onychomycosis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 10, 2024 Category: Dermatology Source Type: research
Correlation Between Nail Thickness and Onychomycosis: Misuse of Antifungal Agents in Patients With Thick Nails
Ann Dermatol. 2024 Apr;36(2):123-124. doi: 10.5021/ad.22.130.NO ABSTRACTPMID:38576251 | DOI:10.5021/ad.22.130 (Source: Annals of Dermatology)
Source: Annals of Dermatology - April 5, 2024 Category: Dermatology Authors: Joon Ki Kim Hyun Cheol Chung Eun Ji Chun Sangseok Kim Chul Woo Kim Source Type: research
Correlation Between Nail Thickness and Onychomycosis: Misuse of Antifungal Agents in Patients With Thick Nails
Ann Dermatol. 2024 Apr;36(2):123-124. doi: 10.5021/ad.22.130.NO ABSTRACTPMID:38576251 | PMC:PMC10995618 | DOI:10.5021/ad.22.130 (Source: Annals of Dermatology)
Source: Annals of Dermatology - April 5, 2024 Category: Dermatology Authors: Joon Ki Kim Hyun Cheol Chung Eun Ji Chun Sangseok Kim Chul Woo Kim Source Type: research
Screening sensibility and antifungal activity after topical application of a synthetic lactoferrin-derived antimicrobial peptide
CONCLUSIONS: This study showed a positive therapeutic effect of a commercial product containing hLF1-11 in the case of 88.9% of the patients with onychomycosis. The present formulation of hLF1-11 into PBS is stable enough to permit storage at room temperature for at least two years.PMID:38463589 | PMC:PMC10918136 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Carlo Brouwer Teun Boekhout Saleh Alwasel Mahfuzur Rahman Ruth Janga Mick M Welling Source Type: research
