NIH-Funded Study Explains Link to Increased Cardiovascular Risks for People with Obstructive Sleep Apnea
July 26, 2023 -- Researchers have found that people with obstructive sleep apnea have an increased cardiovascular risk due to reduced blood oxygen levels, largely explained by interrupted breathing. Obstructive sleep apnea has long been associated... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - July 26, 2023 Category: Pharmaceuticals Source Type: clinical trials

Continuous Positive Airway Pressure plus Mandibular Advancement Therapy (PAPMAT): study protocol for an adaptive randomised crossover trial comparing the benefits and costs of combining two established treatments for obstructive sleep apnoea
DiscussionIf the intervention is shown to be effective and cost-effective in improving adherence in this standard CPAP-eligible OSA patient population it would be relatively straightforward to introduce into existing OSA treatment pathways, within the wider NHS and more widely. Both MAD and CPAP are already used by sleep services so their combination would require only minor adjustments to existing clinical pathways. It would be straightforward to disseminate the results of the study through regional, national, and international respiratory meetings. The health economics analysis would provide cost-effectiveness data to in...
Source: Trials - July 24, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Condition:   Sleep Apnea, Obstructive Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Endotypic Traits and Obstructive Sleep Apnea Surgery
Condition:   Obstructive Sleep Apnea Interventions:   Drug: Acetazolamide 500 MG QHS;   Drug: Eszopiclone 3 mg QHS Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Condition:   Sleep Apnea, Obstructive Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Endotypic Traits and Obstructive Sleep Apnea Surgery
Condition:   Obstructive Sleep Apnea Interventions:   Drug: Acetazolamide 500 MG QHS;   Drug: Eszopiclone 3 mg QHS Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Conditions:   Sleep Apnea, Obstructive;   Sleep-Disordered Breathing Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Endotypic Traits and Obstructive Sleep Apnea Surgery
Condition:   Obstructive Sleep Apnea Interventions:   Drug: Acetazolamide 500 MG QHS;   Drug: Eszopiclone 3 mg QHS Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Conditions:   Sleep Apnea, Obstructive;   Sleep-Disordered Breathing Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Endotypic Traits and Obstructive Sleep Apnea Surgery
Condition:   Obstructive Sleep Apnea Interventions:   Drug: Acetazolamide 500 MG QHS;   Drug: Eszopiclone 3 mg QHS Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Conditions:   Sleep Apnea, Obstructive;   Sleep-Disordered Breathing Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Endotypic Traits and Obstructive Sleep Apnea Surgery
Condition:   Obstructive Sleep Apnea Interventions:   Drug: Acetazolamide 500 MG QHS;   Drug: Eszopiclone 3 mg QHS Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials

Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Conditions:   Sleep Apnea, Obstructive;   Sleep-Disordered Breathing Intervention:   Device: ExVent Sponsor:   Centre for Sleep and Chronobiology, Canada Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2023 Category: Research Source Type: clinical trials