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Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition. « Back to Top Reviewing the Development of Senotherapeutics to Treat Aging https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/ Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Circulating Claudin-5 Correlates with Age and Alzheimer's Disease
In this study, we developed a blood-based assay for CLDN-5 and investigated its diagnostic utility using 100 cognitively normal (control) subjects, 100 patients with MCI, and 100 patients with AD. Plasma CLDN-5 levels were increased in patients with AD (3.08 ng/mL) compared with controls (2.77 ng/mL). The BBB functions as a selective gate for the uptake of essential molecules from blood into the brain and the excretion of harmful molecules from the brain into blood via transporters and receptors on cellular membranes. In addition, the BBB prevents the influx of blood-borne neurotoxins, cells, and pathogens into the ...
Source: Fight Aging! - February 21, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Romantic Obsession Alters The Brain And Makes You Manic (M)
Find out why early love can mimic symptoms of obsessive-compulsive disorder in the brain. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 14, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Neuroscience Social psychology subscribers-only Source Type: blogs

5 Things We Learnt About Investments In Digital Health: Our E-book
At The Medical Futurist (TMF), and especially at The Medical Futurist Institute, we don’t usually deal with investment-related news and announcements. We receive many press releases coming from incubators and venture capital firms each week, but we never share them on our channels. Even though we focus on technologies and trends rather than companies of interest to investors, this doesn’t mean that we don’t keep a close eye on all these developments.  We are in close contact with many digital health startup founders, analyze the technologies they work on and objectively share news relevant to investors. A...
Source: The Medical Futurist - December 19, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Biotechnology Health Sensors & Trackers MySugr theranos invest portable diagnostics Gary rule Kardia CliniCloud tmfi alivecor MagicLeap covid19 digital health investors pandemic ecg R Source Type: blogs

Coupling behavioral health prescriptions with measurement-based care
It can be difficult for patients with substance use disorders, depression, anxiety, or obsessive-compulsive disorder to seek care and commit to a regular schedule of behavioral health care visits. However, telehealth and telepsychiatry have vastly enabled both access and compliance with care. That being said, medication should not be prescribed without proper oversight and care, Read more… Coupling behavioral health prescriptions with measurement-based care originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 29, 2023 Category: General Medicine Authors: Tags: Conditions Psychiatry Source Type: blogs

CMS ’s Policy on Mental Health Therapists Will Work
By JON KOLE Nearly 66 million Americans are currently enrolled in Medicare, a number that will likely swell towards 80 million Americans within the next seven years. These are our mothers, fathers, aunts, uncles, grandparents and friends – and, maybe, you.  A significant portion of these millions of people need mental health services – and, yet, many face long wait times or aren’t able to find a therapist at all. On average, Americans have a waiting period of 48 days before receiving mental health care. At present, two notable provider groups – Marriage and Family Therapists...
Source: The Health Care Blog - October 24, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Headspace Jon Kole Mental Health Therapy workforce Source Type: blogs

OCD Has This Neurochemical Imbalance At Its Heart (M)
Obsessive-compulsive disorder affects around one-in-thirty people in Western nations. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 1, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: OCD subscribers-only Source Type: blogs

Unmasking OCD: Separating fact from fiction [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join us for an episode with guest Brandi Lawless, an associate professor of communications, as we delve into the misconceptions and realities of obsessive-compulsive disorder (OCD). Through her personal journey and expertise, Brandi challenges the popular notion of “being OCD” as a positive attribute Read more… Unmasking OCD: Separating fact from fiction [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 4, 2023 Category: General Medicine Authors: Tags: Podcast Psychiatry Source Type: blogs

Ultrasound is Ultra-Cool
This study is also a major step forward for the exciting possibility of combining focused ultrasound with targeted delivery of medications or antibodies that normally have limited capability to cross the blood brain barrier from the blood to the brain.”  Similarly, researchers at Yonsei University College of Medicine (South Korea) found that focused ultrasound improved the delivery of Alzheimer’s drugs by over eight times.  “While there is no complete cure for dementia, we hope that open BBB [blood brain barrier] surgery using FUS surgery can help give hope to dementia patients,” the lead researcher said. ...
Source: The Health Care Blog - January 25, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech 3D printing ChatGPT DSP Kim Bellard Ultrasound Source Type: blogs

Obsessive Compulsive Disorder (OCD): Symptoms & Types
OCD symptoms and common signs of OCD, types of OCD, its causes and treatment and how to tell it from OCPD. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 30, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Psychology Source Type: blogs

OCT is not “ Obsessive compulsive tomography ”
This is the story of PCI to LAD from the customary bifurcation workshop for the budding experts, which ended up with a compulsive final OCT run-through, triggering a debate on what to do with the side branch. What shall we do next? Just balloon dilate the distal strut Would consider a second stent. Maybe a TAP  depending upon LCX morphology At this stage, I would like to know the FFR or iFR across LCX Jail. Get rid of this OCT, Let me have look at regular CAG. I bet I can make a better decision. Leave it alone if the clinical status & profile is good Leave it alone? Is it not an incomplete Job? Def...
Source: Dr.S.Venkatesan MD - September 8, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized coronary Imaging ILUMEN study oct opitical coherence tomography Source Type: blogs

Coming back from the brink of burnout [PODCAST]
“I understand what it feels like to be in the depths of depression and hopelessness. I have had a lifelong battle with stuttering, obsessive-compulsive tendencies, depression, and suicide. I continually fight these battles and have learned to heal and recover through family, friends, and ultra-running. Since attempting to take my life on September 12, 2009,Read more …Coming back from the brink of burnout [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 10, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Psychiatry Source Type: blogs

2 Major Signs Of Obsessive-Compulsive Disorder (M)
What really underlies obsessive-compulsive disorder? (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 8, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Anxiety subscribers-only Source Type: blogs

Coming back from the brink of burnout
I understand what it feels like to be in the depths of depression and hopelessness. I have had a lifelong battle with stuttering, obsessive-compulsive tendencies, depression, and suicide. I continually fight these battles and have learned to heal and recover through family, friends, and ultra-running. Since attempting to take my life on September 12, 2009,Read more …Coming back from the brink of burnout originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 23, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/anthony-avellino" rel="tag" > Anthony Avellino < /a > < /span > Tags: Physician Psychiatry Source Type: blogs

Ruminating About Symptoms Can Maintain Distress In Those With OCD
By Emily Reynolds Rumination is a key feature of Obsessive-Compulsive Disorder. According to the charity OCD UK, rumination is a “train of prolonged thinking about a question or theme that is undirected and unproductive” — worrying incessantly about a particular issue or question, in other words. Those with OCD may also ruminate on their symptoms themselves: rather than just dwelling on their fears of harming someone or on existential worries, for example, they will also worry about having these thoughts in the first place. It’s this rumination about symptoms that a team of researchers explore in a new study...
Source: BPS RESEARCH DIGEST - October 26, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Mental health Thought Source Type: blogs